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샘암종과 동반된 위 난황막종양- 1예보고와 문헌고찰 및 면역조직학적 연구 -

Adenocarcinoma with Yolk Sac Tumor of the Stomach:Case Report with Review of the Literature and an Immunohistochemical Study

이미자|서재홍|홍란
대한병리학회|2007.10|Journal of Pathology and Translational Medicine|제41권 제5호|pp. 352-357

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참고문헌

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초록

Abstract

Gastric yolk sac tumors are extremely rare with only a few cases reported in the literature. Here, we present the case of a 50-year-old man with an adenocarcinoma and a yolk sac tumor of the stomach, without metastasis to the lymph nodes. The tumor was an early gastric carcinoma confined to the submucosa. Twelve months post-operation the patient was alive with no complications. The yolk sac tumor showed positive labeling for -fetoprotein (AFP), 1-antitrypsin ( 1-AT), cytokeratin (CK) and carcinoembryonic antigen (CEA), but was negative for human chorionic gonadotrophin (hCG), placental alkaline phosphatase (PLAP), epithelial membrane antigen (EMA) and p53. The adenocarcinoma was positive for 1-AT, CK, EMA, and CEA, but was negative for AFP, hCG, PLAP, and p53. These findings suggest that the yolk sac tumor and the adenocarcinoma components are closely related and may represent distinct phenotypes that arise from a common mucosal epithelial cell.

참고문헌 (27)

  1. "Primary germ cell tumors of themediastinum III. Yolk sac tumor, embryonal carcinoma, choriocarcinoma and combined nonteratomatous germ cell tumors of themediastinum-a clinicopathologic and immunohistochemical studyof 64 cases", 80, pp.699~707 (1997)
  2. "Sacrococcygeal germ cell tumors in childhood:an updated experiencewith 118 patients", 16, pp.358~64 (1981)
  3. "cell carcinomawith endodermal sinus tumor-like features of the nasopharynxand paranasal sinuses Clinicopathologic and immunohistochemicalstudy of two cases"
  4. "Pulmonary blastoma with germ cell report of two cases", pp.566~70
  5. "Ovarianendometrioid tumors with yolk sac tumor component an unusualform of ovarian neoplasm Analysis of six cases", 20, pp.1056~1066 (1996)
  6. "Retroperitoneal germ cell tumorsin childhood", 56, pp.602~8 (1985)
  7. "Gastric choriocarcinoma and yolk sac tumorin a man", 16, pp.955~8 (1985)
  8. "Endodermal sinustumor of the stomach", 35, pp.497~505 (1985)
  9. "Yolk sac carcinoma of thestomach with gastrin positivity", 24, pp.927~8 (1993)
  10. "Yolk sac tumor of the stomachwith an adenocarcinomatous component:a case report withimmunohistochemical analysis", 49, pp.557~562 (1999)
  11. "Combined yolk sac tumorand adenocarcinoma in a gastric stump:molecular evidence of clonality", 85, pp.1910~1916 (1999)
  12. "Gastric adenocarcinomawith yolk sac component:a case report and review ofthe literature", 31, pp.85~88 (2000)
  13. "Combined yolk sac tumor and adenocarcinoma of theesophago-gastric junction", 36, pp.589~592 (2004)
  14. "Pure gastric yolk sac tumor thatwas diagnosed after curative resection:case report and review ofliterature", 35, pp.77~81 (2005)
  15. "Combinedchoriocarcinoma and yolk sac tumor arising in Barrett’s esophagus", pp.514~7
  16. "Comparison between the clinicopathologic features of AFP-positiveand AFP-negative gastric cancers", 87, pp.321~5 (1992)
  17. "Uncommon cancers of the stomach In Textbook of uncommon cancers In Textbook of uncommon cancers. 2nd ed", pp.389~394 (1999), Chichester:John Wiley and Son
  18. "n AFP-producing gastric with features of hepatic differentiation", 56, pp.840~8 (1985)
  19. "An analysis of seven cases", hepatoid ade(carcimaof stomach), pp.119~26
  20. "Immunohistochemistry as a diagnosticaid in the evaluation of ovarian tumors", 22, pp.3~32 (2005)
  21. "Alphafetoprotein-producing gastric adenocarcinoma", 26, pp.171~175 (1995)
  22. "AFP-producing gastric carcinoma:multivariate analysis of prognosticfactors in 270 patients", 65, pp.95~101 (2003)
  23. Beckstead JH, "Alkaline phosphatase histochemistry in human germcell neoplasm", 7, pp.341~9 (1983)
  24. Biermann K, "Diagnostic value of markers M2A PLAP and c-KIT in the detection of extragonadal seminomas", 49, pp.290~297 (2006)
  25. Matsunou H, "Alphafetoprotein-producing gastric carcinoma with enteroblastic differentiation", 73, pp.534~40 (1994)
  26. Saigo PE, "Primarygastric choriocarcinoma", 5, pp.333~42 (1981)
  27. Kodama T, "Production of alpha-fetoprotein", pp.1647~55

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