Ovarian Endometrioid Adenocarcinoma with a Yolk Sac Tumor Component
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Ovarian endometrioid adenocarcinoma (EAC) with a yolk sac tumor (YST) component is extremely rare. Only twelve cases have been reported in the English literature. We report here two additional cases of this rare tumor. The YST component showed classic microscopic features, and immunohistochemically stained positive for alpha-fetoprotein (AFP), but negative for cytokeratin 7 (CK7), epithelial membrane antigen (EMA), estrogen receptor (ER) and progesterone receptor (PR). The EAC appeared to blend into the YST in several areas and immunohistochemically stained positive for CK7, EMA, ER, and PR, but negative for AFP.
Abstract
Ovarian endometrioid adenocarcinoma (EAC) with a yolk sac tumor (YST) component is extremely rare. Only twelve cases have been reported in the English literature. We report here two additional cases of this rare tumor. The YST component showed classic microscopic features, and immunohistochemically stained positive for alpha-fetoprotein (AFP), but negative for cytokeratin 7 (CK7), epithelial membrane antigen (EMA), estrogen receptor (ER) and progesterone receptor (PR). The EAC appeared to blend into the YST in several areas and immunohistochemically stained positive for CK7, EMA, ER, and PR, but negative for AFP.
참고문헌 (10)
- Scully RE, "Germ cell tumors: general features and primitive forms. in: Atlas of tumor pathology. Tumors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament", pp.239~266 (1998), Armed Forces Institute of Pathology
- Nogales FF, "Ovari-an endometrioid tumors with yolk sac tumor component, an unusual form of ovarian neoplasm. Analysis of six cases", Am J Surg Pathol, 20, pp.1056~1066 (1996)
- Horiuchi A, "Ovarian yolk sac tumor with endometrioid carcinoma arising from endometriosis in a postmenopausal woman, with special reference to expression of alpha-fetoprotein, sex steroid receptors, and p53", Gynecol Oncol, 70, pp.295~299 (1998)
- Abe A, "A case of ovarian endometrioid adenocarcinoma with a yolk sac tumor component", Int J Gynecol Cancer, 18, pp.168~172 (2008)
- Kamoi S, "A case of ovarian endometrioid adenocarcinoma with yolk sac tumor component in a postmenopausal woman", APMIS, 110, pp.508~514 (2002)
- Kane SV, "Ovarian endometrioid carcinoma with yolk sac component in a young patient: a diagnostic and therapeutic dilemma", Aust N Z J Obstet Gynaecol, 44, pp.364~366 (2004)
- Lopez JM, "Ovarian yolk sac tumor associated with endometrioid carcinoma and mucinous cystadenoma of the ovary", Ann Diagn Pathol, 7, pp.300~305 (2003)
- Rutgers JL, "Ovarian yolk sac tumor arising from an endometrioid carcinoma", Hum Pathol, 18, pp.1296~1299 (1987)
- McBee WC Jr, "Yolk sac tumor of the ovary associated with endometrioid carcinoma with metastasis to the vagina: a case report", Gynecol Oncol, 105, pp.244~247 (2007)
- Ramalingam P, "The use of cytokeratin 7 and EMA in differentiating ovarian yolk sac tumors from endometrioid and clear cell carcinomas", Am J Surg Pathol, 28, pp.1499~1505 (2004)