Primary Malignant Melanoma of the Male Urethra
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Primary malignant melanoma occurring within the male urethra is very rare. Here we report a case of malignant melanoma of the urethra in a 74-year-old man. He presented with asymptomatic gross hematuria for 5 months. His glans penis and adjacent penile skin had become discolored black 10 years ago. Cystourethroscopy showed a smooth oval-shaped elevated mass in the fossa navicularis. There were no abnormal findings in the proximal urethra and urinary bladder. Computed tomography did not detect any inguinal lymph node enlargement or distant metastases. The patient underwent partial penectomy and ilioinguinal lymph node dissection. Grossly, the distal urethra revealed an ovoid pigmented nodule, that measured 1×0.5 cm. Microscopic findings showed a nodular malignant melanoma arising in the urethral mucosa with pagetoid spread to the epidermis of the glans penis. There were no recurrences over a period of 12 months after surgery without chemotherapy. This is the second case of a primary malignant melanoma of the male urethra in Korea.
Abstract
Primary malignant melanoma occurring within the male urethra is very rare. Here we report a case of malignant melanoma of the urethra in a 74-year-old man. He presented with asymptomatic gross hematuria for 5 months. His glans penis and adjacent penile skin had become discolored black 10 years ago. Cystourethroscopy showed a smooth oval-shaped elevated mass in the fossa navicularis. There were no abnormal findings in the proximal urethra and urinary bladder. Computed tomography did not detect any inguinal lymph node enlargement or distant metastases. The patient underwent partial penectomy and ilioinguinal lymph node dissection. Grossly, the distal urethra revealed an ovoid pigmented nodule, that measured 1×0.5 cm. Microscopic findings showed a nodular malignant melanoma arising in the urethral mucosa with pagetoid spread to the epidermis of the glans penis. There were no recurrences over a period of 12 months after surgery without chemotherapy. This is the second case of a primary malignant melanoma of the male urethra in Korea.
참고문헌 (14)
- Katz EE, "Primary malignant melanoma of the urethra", Urology, 65, pp.389~ (2005)
- Oliva E, "Primary malignant melanoma of the urethra:a clinicopathologic analysis of 15 cases", Am J Surg Pathol, 24, pp.785~796 (2000)
- Tyrell HJ, "Melanotic tumor of the urethra", Proc Pathol Soc Dublin, 4, pp.194~ (1871)
- Watanabe J, "Primary malignant melanoma of the male urethra", Int J Urol, 7, pp.351~353 (2000)
- van Geel AN, "Prognosis of primary mucosal penile melanoma:a series of 19 Dutch patients and 47 patients from the literature", Urology, 70, pp.143~147 (2007)
- Manivel JC, "Malignant melanoma of the penis and male urethra:4 case reports and literature review", J Urol, 139, pp.813~816 (1988)
- Weiss J, "Melanoma of the male urethra:surgical approach and pathological analysis", J Urol, 128, pp.382~385 (1982)
- Pow-Sang JM, "Primary malignant melanoma of the male urethra", J Urol, 139, pp.1304~1306 (1988)
- DiMarco DS, "Outcome of surgical treatment for primary malignant melanoma of the female urethra", J Urol, 171(2 Pt 1), pp.765~767 (2004)
- Calcagno L, "Primary malignant melanoma of male urethra", Urology, 37, pp.366~368 (1991)
- 이규광, "남성요도에 발생한 원발성 악성 흑색종", Korean Journal of Urology, 46(7), pp.764~766 (2005), 대한비뇨기과학회
- Nakhleh RE, "Morphologic diversity in malignant melanomas", Am J Clin Pathol, 93, pp.731~740 (1990)
- Yoshizawa T, "Primary malignant melanoma of the female urethra", Urology, 70, pp.1222.e13~1222.e16 (2007)
- Robutti F, "Primary malignant melanoma of the female urethral meatus", Eur Urol, 12, pp.62~63 (1986)