Type and Incidence of Soft Tissue Sarcomas in Korea: 2001-2007
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Background: The Korean Bone and Soft Tissue Pathology Study Group of the Korean Society of Pathologists conducted a nationwide retrospective analysis of soft tissue sarcoma (STS) to pro-vide the clinicopathologic characteristics of STS within the population of the Republic of Korea. Methods: The cases of STS were collected during a 7-year period (2001-2007) from 19 institutes in Korea. All cases were classified according to the histologic criteria proposed by the World Health Organization. Clinicopathologic data were reviewed. Results: Data from 722 patients (median age, 50 years) were collected. Data showed a slight male predominance. The most frequent types of STS in decreasing order were liposarcoma, malignant fibrous histiocytoma, leiomyosarcoma, and synovial sarcoma. STS occurred throughout the body, although approximately half (47.8%) were located in the extremities. The majority of STS was histologically classified as high grade with a large tumor size (>5 cm). The overall survival rate for the patients was 76.3% (median follow-up time, 26 months; range, 1 to 89 months). Histologic grade, tumor size, American Joint Committee on Cancer stage, tumor site, and resection status were prognostic. Significant independent ad¬verse prognostic factors were large tumor size (>5 cm) and tumor site other than extremities. Conclusions: We reported the distribution and characteristics of STS in the Republic of Korea.
Abstract
Background: The Korean Bone and Soft Tissue Pathology Study Group of the Korean Society of Pathologists conducted a nationwide retrospective analysis of soft tissue sarcoma (STS) to pro-vide the clinicopathologic characteristics of STS within the population of the Republic of Korea. Methods: The cases of STS were collected during a 7-year period (2001-2007) from 19 institutes in Korea. All cases were classified according to the histologic criteria proposed by the World Health Organization. Clinicopathologic data were reviewed. Results: Data from 722 patients (median age, 50 years) were collected. Data showed a slight male predominance. The most frequent types of STS in decreasing order were liposarcoma, malignant fibrous histiocytoma, leiomyosarcoma, and synovial sarcoma. STS occurred throughout the body, although approximately half (47.8%) were located in the extremities. The majority of STS was histologically classified as high grade with a large tumor size (>5 cm). The overall survival rate for the patients was 76.3% (median follow-up time, 26 months; range, 1 to 89 months). Histologic grade, tumor size, American Joint Committee on Cancer stage, tumor site, and resection status were prognostic. Significant independent ad¬verse prognostic factors were large tumor size (>5 cm) and tumor site other than extremities. Conclusions: We reported the distribution and characteristics of STS in the Republic of Korea.
참고문헌 (23)
- Weiss SW, "Enzinger and Weiss’s soft tissue tumors. 5th ed" (2008), Mosby Elsevier
- Ross JA, "Trends in the incidence of soft tissue sarcomas in the United States from 1973 through 1987", Cancer, 72, pp.486~490 (1993)
- Jemal A, "Cancer statistics, 2010", CA Cancer J Clin, 60, pp.277~300 (2010)
- Fletcher CD, "Pathology and genetics of tumours of soft tissue and bone" (2002), IARC Press
- Gustafson P, "Soft tissue sarcoma: epidemiology and prognosis in 508 patients", Acta Orthop Scand Suppl, (259), pp.1~31 (1994)
- Gustafson P, "Soft tissue sarcoma of the upper extremity: descriptive data and outcome in a population-based series of 108 adult patients", J Hand Surg Am, 24, pp.668~674 (1999)
- Edge SB, "AJCC cancer staging manual. 7th ed" (2010), Springer
- Annual report of cancer statistics in Korea in 2008, "Korea Central Cancer Registry", Korea Central Cancer Registry, ~ (2010)
- Bauer HC, "Monitoring referral and treatment in soft tissue sarcoma: study based on 1,851 patients from the Scandinavian Sarcoma Group Register", Acta Orthop Scand, 72, pp.150~159 (2001)
- Pisters PW, "Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities", J Clin Oncol, 14, pp.1679~1689 (1996)
- Stoeckle E, "Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group", Cancer, 92, pp.359~368 (2001)
- Trovik CS, "Local recurrence of soft tissue sarcoma. A Scandinavian Sarcoma Group Project", Acta Orthop Scand Suppl, 72, pp.1~31 (2001)
- Mariani L, "Validation and adaptation of a nomogram for predicting the survival of patients with extremity soft tissue sarcoma using a three-grade system", Cancer, 103, pp.402~408 (2005)
- Singer S, "Management of soft-tissue sarcomas: an overview and update", Lancet Oncol, 1, pp.75~85 (2000)
- Le Vay J, "An assessment of prognostic factors in soft-tissue sarcoma of the head and neck", Arch Otolaryngol Head Neck Surg, 120, pp.981~986 (1994)
- Singh RP, "Adult head and neck soft tissue sarcomas: treatment and outcome", Sarcoma, 2008, pp.654987~ (2008)
- Singer S, "Prognostic factors predictive of survival for truncal and retroperitoneal soft-tissue sarcoma", Ann Surg, 221, pp.185~195 (1995)
- Sabolch A, "Risk factors for local recurrence and metastasis in soft tissue sarcomas of the extremity", Am J Clin Oncol (2011)
- Coindre JM, "Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: a study of 1240 patients from the French Federation of Cancer Centers Sarcoma Group", Cancer, 91, pp.1914~1926 (2001)
- van Unnik JA, "Grading of soft tissue sarcomas: experience of the EORTC Soft Tissue and Bone Sarcoma Group", Eur J Cancer, 29A, pp.2089~2093 (1993)
- Engellau J, "Identification of low-risk tumours in histological high-grade soft tissue sarcomas", Eur J Cancer, 43, pp.1927~1934 (2007)
- Engellau J, "Prognostic factors in soft tissue sarcoma: tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence", Acta Orthop Scand Suppl, 75(Suppl 314), pp.1~52 (2004)
- Carneiro A, "A prognostic model for soft tissue sarcoma of the extremities and trunk wall based on size, vascular invasion, necrosis, and growth pattern", Cancer, 117, pp.1279~1287 (2011)