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Granular Cell Astrocytoma: Report of a Case

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초록

We report here a rare case of granular cell astrocytoma. A 75-year-old man was admitted to Inha University Hospital with a three-month history of language deterioration. In a magnetic resonance imaging, a 6.5 cm-sized heterogeneous enhancing mass was seen in both the frontal lobes and the anterior genu of the corpus callosum. A stereotactic biopsy was performed. The tumor was composed of large and small round cells with abundant intracytoplasmic granules. The nuclei were bland, round to oval, and often eccentrically located. The cytoplasm of the tumor cells was positive for glial fibrillary acidic protein and S-100 protein.

Abstract

We report here a rare case of granular cell astrocytoma. A 75-year-old man was admitted to Inha University Hospital with a three-month history of language deterioration. In a magnetic resonance imaging, a 6.5 cm-sized heterogeneous enhancing mass was seen in both the frontal lobes and the anterior genu of the corpus callosum. A stereotactic biopsy was performed. The tumor was composed of large and small round cells with abundant intracytoplasmic granules. The nuclei were bland, round to oval, and often eccentrically located. The cytoplasm of the tumor cells was positive for glial fibrillary acidic protein and S-100 protein.

참고문헌 (7)

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  4. Brat DJ, "Infiltrative astrocytomas with granular cell features (granular cell astrocytomas): a study of histopathologic features, grading, and outcome", Am J Surg Pathol, 26, pp.750~757 (2002)
  5. 신은, "Granular cell astrocytoma", PATHOLOGY RESEARCH AND PRACTICE, 203(1), pp.57~62 (2007), ELSEVIER GMBH
  6. Lee D, "Cerebral granular cell tumor", Neuropathology, 28, pp.417~421 (2008)
  7. Arvanitis LD, "Cytologic features of granular cell astrocytoma in crush preparations", Diagn Cytopathol, 39, pp.77~79 (2011)

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