A Rare Case of Primary Tubular Adenocarcinoma of the Thymus, Enteric Immunophenotype: A Case Study and Review of the Literature
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Thymic carcinomas are uncommon malignant tumors, and thymic adenocarcinomas are extremely rare. Here, we describe a case of primary thymic adenocarcinoma in a 59-year-old woman. Histological examination of the tumor revealed tubular morphology with expression of cytokeratin 20 and caudal-type homeobox 2 according to immunohistochemistry, suggesting enteric features. Extensive clinical and radiological studies excluded the possibility of an extrathymic primary tumor. A review of the literature revealed only two global cases of primary tubular adenocarcinomas of the thymus with enteric immunophenotype.
Abstract
Thymic carcinomas are uncommon malignant tumors, and thymic adenocarcinomas are extremely rare. Here, we describe a case of primary thymic adenocarcinoma in a 59-year-old woman. Histological examination of the tumor revealed tubular morphology with expression of cytokeratin 20 and caudal-type homeobox 2 according to immunohistochemistry, suggesting enteric features. Extensive clinical and radiological studies excluded the possibility of an extrathymic primary tumor. A review of the literature revealed only two global cases of primary tubular adenocarcinomas of the thymus with enteric immunophenotype.
참고문헌 (17)
- Müller-Hermelink HK, "World Health Organization classification of tumours: pathology and genetics of tumours of the lung, pleura, thymus and heart", pp.184~ (2004), IARC Press
- Moriyama S, "A case of adenocarcinoma of the thymus", Nihon Kyobu Geka Gakkai Zasshi, 37, pp.717~722 (1989)
- Maghbool M, "Primary adenocarcinoma of the thymus : an immunohistochemical and molecular study with review of the literature", BMC Clin Pathol, 13, pp.17~ (2013)
- Matsuno Y, "Papillary carcinoma of the thymus : report of four cases of a new microscopic type of thymic carcinoma", Am J Surg Pathol, 22, pp.873~880 (1998)
- Yoshino M, "Papillary carcinoma of the thymus gland", Ann Thorac Surg, 80, pp.741~742 (2005)
- Furtado A, "Papillary adenocarcinoma of the thymus : case report and review of the literature", Int J Surg Pathol, 18, pp.530~533 (2010)
- Choi WW, "Adenocarcinoma of the thymus: report of two cases, including a previously undescribed mucinous subtype", Am J Surg Pathol, 27, pp.124~130 (2003)
- Ra SH, "Mucinous adenocarcinomas of the thymus : report of 2 cases and review of the literature", Am J Surg Pathol, 31, pp.1330~1336 (2007)
- Jamshid Abdul-Ghafar, "Primary Thymic Mucinous Adenocarcinoma: A Case Report", Journal of Pathology and Translational Medicine, 46(4), pp.377~381 (2012), 대한병리학회[DOI]
- Sawai T, "Tubular adenocarcinoma of the thymus:case report and review of the literature", Int J Surg Pathol, 14, pp.243~246 (2006)
- Misao T, "Primary thymic adenocarcinoma with production of carbohydrate antigen 19-9 and carcinoembryonic antigen", Jpn J Thorac Cardiovasc Surg, 52, pp.30~32 (2004)
- Moser B, "Adenocarcinoma of the thymus, enteric type: report of 2 cases, and proposal for a novel subtype of thymic carcinoma", Am J Surg Pathol, 39, pp.541~548 (2015)
- Ishiwata T, "Thymic adenocarcinoma with sarcomatoid features characterized by intracaval tumor growth : report of a case", Surg Today, 40, pp.1068~1072 (2010)
- Teramoto K, "Thymic papillo-tubular adenocarcinoma containing a cyst: report of a case", Surg Today, 42, pp.988~991 (2012)
- Suster S, "Thymic carcinoma : a clinicopathologic study of 60cases", Cancer, 67, pp.1025~1032 (1991)
- Wang S, "Prognostic factors of patients with thymic carcinoma after surgery : a retrospective analysis of 58 cases", World J Surg, 38, pp.2032~2038 (2014)
- Filosso PL, "Outcome of surgically resected thymic carcinoma : a multicenter experience", Lung Cancer, 83, pp.205~210 (2014)
