본문 바로가기
KERD
논문KCI 등재

Nodular Fasciitis of External Auditory Canal

0

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류병리학

초록

Nodular fasciitis is a pseudosarcomatous reactive process composed of fibroblasts and myofibroblasts, and it is most common in the upper extremities. Nodular fasciitis of the external auditory canal is rare. To the best of our knowledge, less than 20 cases have been reported to date. We present a case of nodular fasciitis arising in the cartilaginous part of the external auditory canal. A 19-year-old man complained of an auricular mass with pruritus. Computed tomography showed a 1.7 cm sized soft tissue mass in the right external auditory canal, and total excision was performed. Histologic examination revealed spindle or stellate cells proliferation in a fascicular and storiform pattern. Lymphoid cells and erythrocytes were intermixed with tumor cells. The stroma was myxoid to hyalinized with a few microcysts. The tumor cells were immunoreactive for smooth muscle actin, but not for desmin, caldesmon, CD34, S-100, anaplastic lymphoma kinase, and cytokeratin. The patient has been doing well during the 1 year follow-up period.

Abstract

Nodular fasciitis is a pseudosarcomatous reactive process composed of fibroblasts and myofibroblasts, and it is most common in the upper extremities. Nodular fasciitis of the external auditory canal is rare. To the best of our knowledge, less than 20 cases have been reported to date. We present a case of nodular fasciitis arising in the cartilaginous part of the external auditory canal. A 19-year-old man complained of an auricular mass with pruritus. Computed tomography showed a 1.7 cm sized soft tissue mass in the right external auditory canal, and total excision was performed. Histologic examination revealed spindle or stellate cells proliferation in a fascicular and storiform pattern. Lymphoid cells and erythrocytes were intermixed with tumor cells. The stroma was myxoid to hyalinized with a few microcysts. The tumor cells were immunoreactive for smooth muscle actin, but not for desmin, caldesmon, CD34, S-100, anaplastic lymphoma kinase, and cytokeratin. The patient has been doing well during the 1 year follow-up period.

참고문헌 (14)

  1. Konwaler BE, "Subcutaneous pseudosarcomatous fibromatosis (fasciitis)", Am J Clin Pathol, 25, pp.241~252 (1955)
  2. Weiss SW, "Enzinger and Weiss’s soft tissue tumors" (2008), Mosby
  3. Thompson LD, "Nodular fasciitis of the external ear region: a clinicopathologic study of 50 cases", Ann Diagn Pathol, 5, pp.191~198 (2001)
  4. Abdel-Aziz M, "Nodular fasciitis of the external auditory canal in six Egyptian children", Int J Pediatr Otorhinolaryngol, 72, pp.643~646 (2008)
  5. Peng WX, "Nodular fasciitis in the parotid gland: a case report and review of the literature", Diagn Cytopathol, 41, pp.829~833 (2013)
  6. Jung KH, "Inflammatory myofibroblastic tumor involving ear lobule", Auris Nasus Larynx, 39, pp.631~633 (2012)
  7. Bhattacharya B, "Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions", Am J Surg Pathol, 29, pp.653~659 (2005)
  8. Morrissey G, "Cellular benign fibrous histiocytoma of the external auditory meatus", J Laryngol Otol, 110, pp.98~100 (1996)
  9. Rezk S, "Solitary fibrous tumor of the auditory canal", Arch Pathol Lab Med, 128, pp.e169~171 (2004)
  10. Kim JR, "Nodular fasciitis (13 cases analysis)", Korean J Pathol, 22, pp.190~194 (1998)
  11. Meng GZ, "Myofibroblastic sarcoma vs nodular fasciitis: a comparative study of chromosomal imbalances", Am J Clin Pathol, 131, pp.701~709 (2009)
  12. Erickson-Johnson MR, "Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion", Lab Invest, 91, pp.1427~1433 (2011)
  13. Amary MF, "Detection of USP6 gene rearrangement in nodular fasciitis: an important diagnostic tool", Virchows Arch, 463, pp.97~98 (2013)
  14. Oliveira AM, "USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis", Hum Patho, 45, pp.1~11 (2014)

관련 논문AI추천

이 간행물의 다른 논문 (11건)