Squamous Metaplasia in Pleomorphic Adenoma: A Diagnostic and Prognostic Enigma
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Pleomorphic adenoma (PA) is the most common benign salivary gland tumor. Histologically, squamous metaplasia has been reported in PA, but has rarely been documented as being extensive enough to cause significant misdiagnosis. Here, we present an unusual case of PA in a 50-yearold female patient presenting with swelling on the postero-lateral aspect of the palate for a week. Histopathologically, the tumor exhibited the features of conventional PA with extensive squamous metaplasia and giant keratotic lamellae in cyst-like areas. Such exuberant squamous metaplasia and keratin can be a diagnostic and prognostic pitfall and lead to overtreatment of the patient.
Abstract
Pleomorphic adenoma (PA) is the most common benign salivary gland tumor. Histologically, squamous metaplasia has been reported in PA, but has rarely been documented as being extensive enough to cause significant misdiagnosis. Here, we present an unusual case of PA in a 50-yearold female patient presenting with swelling on the postero-lateral aspect of the palate for a week. Histopathologically, the tumor exhibited the features of conventional PA with extensive squamous metaplasia and giant keratotic lamellae in cyst-like areas. Such exuberant squamous metaplasia and keratin can be a diagnostic and prognostic pitfall and lead to overtreatment of the patient.
참고문헌 (10)
- Neville B, "Oral and maxillofacial pathology", pp.473~506 (2009), Elsevier
- Rajendran R, "Shafer’s text book of oral pathology", pp.223~257 (2012), Elsevier
- Kaveri H, "Cystic and florid squamous metaplasia in pleomorphic adenoma of palate: a diagnostic dilemma", Asian J Med Sci, 5, pp.108~110 (2014)
- Dardick I, "Salivary gland components involved in the formation of squamous metaplasia", Am J Pathol, 119, pp.33~43 (1985)
- Jaishankar HP, "Florid squamous metaplasia and keratin cyst formation in palatal minor salivary gland tumor: a diagnostic challenge", Int J Health Sci Res, 6, pp.516~520 (2016)
- Compagno J, "Intranasal mixed tumors (pleomorphic adenomas): a clinicopathologic study of 40 cases", Am J Clin Pathol, 68, pp.213~218 (1977)
- Takegawa K, "Induction of squamous cell carcinomas in the salivary glands of rats by potassium iodide", Jpn J Cancer Res, 89, pp.105~109 (1998)
- Lam KY, "Palatal pleomorphic adenoma with florid squamous metaplasia: a potential diagnostic pitfall", J Oral Pathol Med, 27, pp.407~410 (1998)
- Lim S, "Pleomorphic adenoma with exuberant squamous metaplasia and keratin cysts mimicking squamous cell carcinoma in minor salivary gland", Open J Pathol, 3, pp.113~116 (2013)
- Goulart MC, "Pleomorphic adenoma with extensive squamous metaplasia and keratin cyst formations in minor salivary gland: a case report", J Appl Oral Sci, 19, pp.182~188 (2011)