귀밑샘에 발생한 경화성 점액표피양암종 - 1예 보고 -
Sclerosing Mucoepidermoid Carcinoma of the Parotid Gland- A Case Report -
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Sclerosing mucoepidermoid carcinoma (SMEC) is a very rare tumor of the salivary gland. There have been eight cases of SMEC reported in the medical literature; this is the first reported case in Korea. A 51-year-old woman presented with a right infra-auricular mass that she had for 3 years. We performed superficial parotidectomy. Grossly, the resected parotid gland showed a well-circumscribed firm mass. Histologically, the tumor consisted of central solid or ductal tumor nests within a dense fibrous stroma surrounded by peripheral lymphoid infiltration. The tumor nests were composed of squamous, intermediate and mucin-secreting cells. However, the tumor cells lacked mitosis and nuclear anaplasia. The lymphoid cells were mostly composed of lymphocytes and plasma cells with occasional eosinophils and neutrophils. Immunohistochemically, the tumor cells were positive for high- and low- molecular weight cytokeratins, cytokeratin 7, p16INK4A, Bcl-2 and cyclin D1. The patient also underwent radiation therapy. We report here on a case of SMEC of the parotid gland along with the immunohistochemical characteristics, and we review the relevant literature.
Abstract
There have been eight cases of SMEC reported in the medical literature; this is the first reported case in Korea. A 51-year-old woman presented with a right infra-auricular mass that she had for 3 years. We performed superficial parotidectomy. Grossly, the resected parotid gland showed a well-circumscribed firm mass. Histologically, the tumor consisted of central solid or ductal tumor nests within a dense fibrous stroma surrounded by peripheral lymphoid infiltration. The tumor nests were composed of squamous, intermediate and mucin-secreting cells. However, the tumor cells lacked mitosis and nuclear anaplasia. The lymphoid cells were mostly composed of lymphocytes and plasma cells with occasional eosinophils and neutrophils. Immunohistochemically, the tumor cells were positive for high- and low- molecular weight cytokeratins, cytokeratin 7, p16INK4A, Bcl-2 and cyclin D1. The patient also underwent radiation therapy. We report here on a case of SMEC of the parotid gland along with the immunohistochemical characteristics, and we review the relevant literature.
참고문헌 (10)
- "Tumors of the salivary glands. Atlas of tumor pathology. Third series, fasc. 17", pp.155~172 (1996), Washington, D.C.: Armed Forces Institute of Pathology, under the auspices of Universities Associated
- "Sclerosing mucoepidermoid tumour of the parotidgland report of a case", pp.203~7
- "Sclerosing mucoepidermoid carcinoma of the parotid", 83, pp.685~690 (1997)
- "Sclerosing mucoepidermoid carcinoma of minor salivary glands: a case report", 35, pp.283~384 (1999)
- "Sclerosing mucoepidermoid carcinoma with eosinophilia of the salivary glands", 198, pp.305~310 (2002)
- "Sclerosing mucoepidermoidcarcinoma of the parotid gland", 128, pp.1046~1049 (2004)
- "Sclerosing mucoepidermoidcarcinoma of the oral cavity", 34, pp.187~189 (2005)
- "The specific distributionof dendritic interstitial cells at the tumor border of major salivarygland pleomorphic adenomas", 12, pp.445~449 (1999)
- "Dendritic interstitial and myofibroblasticcells at the border of salivary gland tumors", 125, pp.232~236 (2001)
- "Calretinin, CD34, and alpha-smooth muscle actin in the identification of peritoneal invasive implants of serous borderline tumors of the ovary", 19, pp.364~372 (2006)