A Rare Case of Angioleiomyoma Arising in the Subglottic Area to Upper Trachea of a Patient with Underlying Asthma
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Angioleiomyoma is a rare disease that is histologically characterized by smooth muscle cells arranged around vascular spaces. Although angioleiomyomas occur rarely in the head and neck region, they can cause various symptoms according the site involved. Here, we present a 44-year-old male patient with a 15-year history of asthma, who presented with recent onset of chest discomfort,globus sensation and throat pain. Medication was not effective in relieving his symptoms, and further evaluation revealed a polypoid ovoid mass, almost obstructing the airway at the border of the larynx and upper trachea on chest computed tomography. The mass was completely resected via a rigid bronchoscopy procedure. Histopathologic examination revealed that the excised mass was angioleiomyoma, which was immunohistochemically positive for smooth muscle actin and negative for desmin.
Abstract
Angioleiomyoma is a rare disease that is histologically characterized by smooth muscle cells arranged around vascular spaces. Although angioleiomyomas occur rarely in the head and neck region, they can cause various symptoms according the site involved. Here, we present a 44-year-old male patient with a 15-year history of asthma, who presented with recent onset of chest discomfort,globus sensation and throat pain. Medication was not effective in relieving his symptoms, and further evaluation revealed a polypoid ovoid mass, almost obstructing the airway at the border of the larynx and upper trachea on chest computed tomography. The mass was completely resected via a rigid bronchoscopy procedure. Histopathologic examination revealed that the excised mass was angioleiomyoma, which was immunohistochemically positive for smooth muscle actin and negative for desmin.
참고문헌 (8)
- Fletcher CD, "WHO classification of tumours of soft tissue and bone" (2013), IARC Press
- Hachisuga T, "Angioleiomyoma: a clinicopathologic reappraisal of 562 cases", Cancer, 54, pp.126~130 (1984)
- Wang CP, "Vascular leiomyoma of the head and neck", Laryngoscope, 114, pp.661~665 (2004)
- Xu Y, "Vascular leiomyoma of the larynx: a rare entity: three case reports and literature review", ORL J Otorhinolaryngol Relat Spec, 70, pp.264~267 (2008)
- Hope N, "Angioleiomyoma of the larynx: beware the subglottic lesion", BMJ Case Rep, 2015, pp.bcr2015213~ (2015)
- Matsuyama A, "Angioleiomyoma: a clinicopathologic and immunohistochemical reappraisal with special reference to the correlation with myopericytoma", Hum Pathol, 38, pp.645~651 (2007)
- Lundgren L, "Intermediate and fine filaments of vascular leiomyomas (angiomyoma), leiomyoma and leiomyosarcomas of large veins", APMIS, 97, pp.637~645 (1989)
- Hasegawa T, "Mechanism of pain and cytoskeletal properties in angioleiomyomas: an immunohistochemical study", Pathol Int, 44, pp.66~72 (1994)
