Malignant Pleural Effusion from Metastatic Prostate Cancer: A Case Report with Unusual Cytologic Findings
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We present a case of 55-year-old man who complained of dyspnea and sputum for a month. He was an ex-smoker with a history of prostate cancer and pulmonary tuberculosis. Chest radiographs revealed bilateral pleural effusions of a small to moderate amount. Pigtail catheters were inserted for drainage. The pleural fluid consisted of large clusters and tightly cohesive groups of malignant cells, which however could not be ascribed to prostate cancer with certainty. We performed immunocytochemical panel studies to determine the origin of cancer metastasis. The immunostaining results were positive for prostate-specific antigen, alpha-methylacyl-coenzyme A racemase, and Nkx 3.1, consistent with prostate cancer. Pleural effusion associated with prostate cancer is rare. To our knowledge, this is the first case report in Korea to describe cytologic features of malignant pleural effusion associated with prostate cancer.
Abstract
We present a case of 55-year-old man who complained of dyspnea and sputum for a month. He was an ex-smoker with a history of prostate cancer and pulmonary tuberculosis. Chest radiographs revealed bilateral pleural effusions of a small to moderate amount. Pigtail catheters were inserted for drainage. The pleural fluid consisted of large clusters and tightly cohesive groups of malignant cells, which however could not be ascribed to prostate cancer with certainty. We performed immunocytochemical panel studies to determine the origin of cancer metastasis. The immunostaining results were positive for prostate-specific antigen, alpha-methylacyl-coenzyme A racemase, and Nkx 3.1, consistent with prostate cancer. Pleural effusion associated with prostate cancer is rare. To our knowledge, this is the first case report in Korea to describe cytologic features of malignant pleural effusion associated with prostate cancer.
참고문헌 (16)
- Egan AM, "Malignant pleural effusion", QJM, 107, pp.179~184 (2014)[DOI]
- Thomas JM, "Malignant pleural effusions: a review", Clin Chest Med, 34, pp.459~471 (2013)[DOI]
- Lim MH, "Diagnosing malignant pleural effusions: how do we compare?", N Z Med J, 126, pp.42~48 (2013)
- Bubendorf L, "Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients", Hum Pathol, 31, pp.578~583 (2000)[DOI]
- Vinjamoori AH, "Atypical metastases from prostate cancer: 10-year experience at a single institution", AJR Am J Roentgenol, 199, pp.367~372 (2012)[DOI]
- Ani I, "Metastatic prostate cancer with malignant ascites: a case report and literature review", Can Urol Assoc J, 7, pp.E248~E250 (2013)[DOI]
- Bajpai PA, "A case of recurrent massive right sided pleural effusion-an unusual presentation of carcinoma prostate", Lung India, 31, pp.423~424 (2014)[DOI]
- dos Santos VM, "Massive pleural effusion due to metastasis of prostate cancer", West Indian Med J, 60, pp.690~693 (2011)
- Knight JC, "Malignant pleural effusion from prostate adenocarcinoma", Respir Med Case Rep, 13, pp.24~25 (2014)
- Saif MW, "Malignant ascites associated with carcinoma of the prostate", J Appl Res, 5, pp.305~311 (2005)
- Saif MW, "Malignant ascites as only manifestation of metastatic prostate cancer", Prostate Cancer Prostatic Dis, 2, pp.290~293 (1999)[DOI]
- Mai KT, "Secondary prostatic adenocarcinoma: a cytopathological study of 50 cases", Diagn Cytopathol, 35, pp.91~95 (2007)[DOI]
- Renshaw AA, "Cytology of metastatic adenocarcinoma of the prostate in pleural effusions", Diagn Cytopathol, 15, pp.103~107 (1996)[DOI]
- Carrascosa M, "Malignant pleural effusion from prostatic adenocarcinoma resolved with hormonal therapy", Chest, 105, pp.1577~1578 (1994)[DOI]
- Shimizu T, "Severe flare-up in a prostate cancer patient treated with luteinizing hormone-releasing hormone analogue depot", Hinyokika Kiyo, 39, pp.953~955 (1993)
- Mestitz H, "Intrathoracic manifestations of disseminated prostatic adenocarcinoma", Respir Med, 83, pp.161~166 (1989)[DOI]