Heterotopic mesenteric ossification: a report of two cases
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Heterotopic mesenteric ossification (HMO) is abnormal bone formation in tissues which usually do not undergo ossification. There are approximately 75 cases reported worldwide. We present two cases of HMO. The first case is that of a 39-year-old man who presented with abdominal pain and a computerized tomography scan of the abdomen and pelvis revealed an apple core lesion resulting in small bowel obstruction. The second case is that of a 36-year-old woman who presented 2 months after undergoing robotic gastric sleeve resection complaining of weakness and emesis. An esophagogram revealed kinking at the distal esophagus. Surgical resection was performed in both, yielding the diagnosis of HMO. There are various theories as to the pathophysiology of HMO, but no clearly defined mechanism has been established. Management should be conservative whenever possible to prevent further ossification with subsequent surgical intervention.
Abstract
Heterotopic mesenteric ossification (HMO) is abnormal bone formation in tissues which usually do not undergo ossification. There are approximately 75 cases reported worldwide. We present two cases of HMO. The first case is that of a 39-year-old man who presented with abdominal pain and a computerized tomography scan of the abdomen and pelvis revealed an apple core lesion resulting in small bowel obstruction. The second case is that of a 36-year-old woman who presented 2 months after undergoing robotic gastric sleeve resection complaining of weakness and emesis. An esophagogram revealed kinking at the distal esophagus. Surgical resection was performed in both, yielding the diagnosis of HMO. There are various theories as to the pathophysiology of HMO, but no clearly defined mechanism has been established. Management should be conservative whenever possible to prevent further ossification with subsequent surgical intervention.
참고문헌 (18)
- Balboni TA, "Heterotopic ossification : pathophysiology, clinical features, and the role of radiotherapy for prophylaxis", Int J Radiat Oncol Biol Phys, 65, pp.1289~1299 (2006)
- Naraghi FF, "Heterotopic ossification", Orthopedics, 19, pp.145~151 (1996)
- Lemeshev Y, "Heterotopic bone formation associated with intestinal obstruction and small bowel resection", Ala J Med Sci, 20, pp.314~317 (1983)
- Hansen O, "Heterotopic ossification of the intestinal mesentery : report of a case following intraabdominal surgery", Pathol Res Pract, 176, pp.125~130 (1983)
- Wilson JD, "Heterotopic mesenteric ossification(‘intraabdominal myositis ossificans’) : report of five cases", Am J Surg Pathol, 23, pp.1464~1470 (1999)
- Ferreira C, "Heterotopic mesenteric and abdominal wall ossification : two case reports in one institution", Int J Surg Case Rep, 37, pp.22~25 (2017)
- AlthaqafiRM, "A case report and literature review of heterotopic mesenteric ossification", Int J Surg Case Rep, 82, pp.105905~ (2021)
- Sarraf K, "Laparoscopic enterolysis of congenital band precipitating pathogenic heterotopic mesenteric ossification requiring hemicolectomy : a case report", Am J Case Rep, 23, pp.e934910~ (2022)
- McCarthy EF, "Heterotopic ossification : a review", Skeletal Radiol, 34, pp.609~619 (2005)
- Binesh F, "Heterotopic mesenteric ossification : report of a case and review of the literature", BMJ Case Rep, 2012, pp.bcr0220125~ (2012)
- Gaffey MJ, "Heterotopic ossification of soft tissue : a review with emphasis on ossification within abdominal surgical scars", Anat Pathol, 3, pp.195~208 (1998)
- Xu Y, "Heterotopic ossification : clinical features, basic researches, and mechanical stimulations", Front Cell Dev Biol, 10, pp.770931~ (2022)
- Myers MA, "Heterotopic ossification within the smallbowel mesentery", Arch Surg, 124, pp.982~983 (1989)
- Hicks CW, "Mesenteric calcification following abdominal stab wound", Int J Surg Case Rep, 5, pp.476~479 (2014)
- Leblanc E, "BMP-9-induced muscle heterotopic ossification requires changes to the skeletal muscle microenvironment", J Bone Miner Res, 26, pp.1166~1177 (2011)
- Guo X, "Signaling cross-talk between TGF-beta", BMP and other pathways, 2009, pp.19, 71~88
- Koolen PG, "Heterotopic ossifications in midline abdominal scars : a critical review of the literature", Eur J Vasc Endovasc Surg, 40, pp.155~159 (2010)
- Kan L, "Substance P signaling mediates BMP-dependent heterotopic ossification", J Cell Biochem, 112, pp.2759~2772 (2011)