본문 바로가기
KERD
논문KCI 등재

Primary epithelioid inflammatory myofibroblastic sarcoma of the brain with EML4::ALK fusion mimicking intra-axial glioma: a case report and brief literature review

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류병리학

초록

An aggressive subtype of inflammatory myofibroblastic tumor, epithelioid inflammatory myofibroblastic sarcoma occurs primarily inside the abdominal cavity, followed by a pulmonary localization. Most harbor anaplastic lymphoma kinase (ALK) gene rearrangements, with RANBP2 and RRBP1 among the well-documented fusion partners. We report the second case of primary epithelioid inflammatory myofibroblastic sarcoma of the brain, with a well-known EML4::ALK fusion. The case is notable for its intra-axial presentation that clinico-radiologically mimicked glioma.

Abstract

An aggressive subtype of inflammatory myofibroblastic tumor, epithelioid inflammatory myofibroblastic sarcoma occurs primarily inside the abdominal cavity, followed by a pulmonary localization. Most harbor anaplastic lymphoma kinase (ALK) gene rearrangements, with RANBP2 and RRBP1 among the well-documented fusion partners. We report the second case of primary epithelioid inflammatory myofibroblastic sarcoma of the brain, with a well-known EML4::ALK fusion. The case is notable for its intra-axial presentation that clinico-radiologically mimicked glioma.

참고문헌 (16)

  1. Marino-Enriquez A, "Epithelioid inflammatory myofibroblastic sarcoma : an aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK", Am J Surg Pathol, 35, pp.135~144 (2011)
  2. Coffin CM, "Extrapulmonary inflammatory myofibroblastic tumor(inflammatory pseudotumor) : a clinicopathologic and immunohistochemical study of 84 cases", Am J Surg Pathol, 19, pp.859~872 (1995)
  3. Gleason BC, "Inflammatory myofibroblastic tumours : where are we now?", J Clin Pathol, 61, pp.428~437 (2008)
  4. Chopra S, "Epithelioid inflammatory myofibroblastic sarcoma with VCL-ALK fusion of central nervous system : case report and brief review of the literature", Brain Tumor Pathol, 39, pp.35~42 (2022)
  5. WHO Classification of Tumors Editorial Board, "WHO classification of tumours: central nervous system tumours" (2021), International Agency for Research on Cancer
  6. Yu L, "Epithelioid inflammatory myofibroblastic sarcoma : a clinicopathological, immunohistochemical and molecular cytogenetic analysis of five additional cases and review of the literature", Diagn Pathol, 11, pp.67~ (2016)
  7. Lee JC, "ALK oncoproteins in atypical inflammatory myofibroblastic tumours : novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma", J Pathol, 241, pp.316~323 (2017)
  8. Singh P, "Primary pulmonary epithelioid inflammatory myofibroblastic sarcoma : a rare entity and a literature review", J Pathol Transl Med, 56, pp.231~237 (2022)
  9. Yamamoto H, "ALK, ROS1 and NTRK3gene rearrangements in inflammatory myofibroblastic tumours", Histopathology, 69, pp.72~83 (2016)
  10. Drilon A, "Efficacy of larotrectinib in TRK fusion-positive cancers in adults and children", N Engl J Med, 378, pp.731~739 (2018)
  11. Lovly CM, "Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions", Cancer Discov, 4, pp.889~895 (2014)
  12. Sokai A, "Pulmonary inflammatory myofibroblastic tumor harboring EML4-ALK fusion gene", Jpn J Clin Oncol, 44, pp.93~96 (2014)
  13. Jiang Q, "Identification of EML4-ALK as an alternative fusion gene in epithelioid inflammatory myofibroblastic sarcoma", Orphanet J Rare Dis, 12, pp.97~ (2017)
  14. Fletcher CD, "WHO classification of tumours of soft tissue and bone" (2013), IARC Press
  15. WHO Classification of Tumors Editorial Board, "WHO classification of tumours: breast tumours" (2019), International Agency for Research on Cancer
  16. Zhou L, "Intracranial inflammatory myofibroblastic tumor : a literature review and a rare case misdiagnosed as acoustic neuroma", Diagnostics (Basel), 13, pp.2725~ (2023)

관련 논문AI추천

Primary pulmonary epithelioid inflammatory myofibroblastic sarcoma: a rare entity and a literature reviewAruna Nambirajan, Deepali Jain, Manish Kumar Gaur, Prabhat Singh Malik, Priyanka Singh, Rahul Raj, Sunil Kumar대한병리학회 · Journal of Pathology and Translational Medicine2022 · 제56권 제4호Clinicopathological Analysis and Treatment of Adult Patients with Inflammatory Myofibroblastic Tumor: A 15-Year Single- Center StudyChengcheng Gong, Chunmeng Wang, Jian Wang, Jieyun Zhang, Lin Yu, Wanjing Feng, Xiaowei Zhang, Xin Liu, Yanjing Guo, Yong Chen, Youzhou Sang, Zhiguo Luo대한암학회 · Cancer Research and Treatment2023 · 제55권 제3호Rhabdomyosarcoma of the skull with EWSR1 fusion and ALK and cytokeratin expression: a case report박지은, 송상우, 송준선, 안형록, 조경자대한병리학회 · Journal of Pathology and Translational Medicine2024 · 제58권 제5호ALK Inhibition in a Patient with Inflammatory Myofibroblastic Tumor Harboring CARS1-ALK Fusion곽윤진, 김미소, 김시현, 김지현, 박태근, 배정모, 윤홍석, 최송지대한암학회 · Cancer Research and Treatment2025 · 제57권 제3호A Case of Simultaneously Diagnosed Lung Adenocarcinoma and Endobronchial Inflammatory Myofibroblastic Tumor with Two Distinct Types of ALK TranslocationChun Huang, Dian Ren, Leina Sun, Qi Li, Qiusong Chen, Shikang Zhao, Shuo Li, Song Xu, Tao Shi, Wei Liu, Zuoqing Song대한암학회 · Cancer Research and Treatment2021 · 제53권 제2호Primary Central Nervous System ALK Positive Anaplastic Large Cell Lymphoma with Predominantly Leptomeningeal Involvement in an Adult고영혜, 김석진, 박상희, 박재성, 박희정, 설호준연세대학교의과대학 · Yonsei Medical Journal2013 · 제54권 제3호

이 간행물의 다른 논문 (4건)