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구강 편평태선 환자에서 steroid와 cyclosporine의 국소 도포 효과

The effect of topical application with steroid and cyclosporine on oral lichenplanus patients

박성진|이종호|김명진|박지현|윤필영|정성창|명훈|고홍섭|홍순민
대한구강악안면외과학회 (Korean Association Of Oral And Maxillofacial Surgeons)|2004.06|대한구강악안면외과학회지 (Journal of the Korean Association of Oral and Maxillofacial Surgeons)|제30권 제3호|pp. 203-210

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참고문헌

주제분류치의학

초록

Abstract

The purpose of this study was comparing the effectiveness in the topical applications of cyclosporine with that of steroid, the conventional and standard drug in the treatment of oral lichen planus. 21 patients with oral lichen planus were treated with cyclosporine (n=11) or steroid (n=10) by random allocations. They were recalled 2 weeks, 4 weeks, and 8 weeks after initial treatments. In each recall, the lesion size, clinical symptoms like pain or burning sensation, and side effects were evaluated. The differences of these measurements were compared and the effects of each drug were checked. In reticulation types, steroid showed higher effectivity than cyclosporine and this difference was significant statistically. But in erythema type lesions, either drug showed no significant recovery, statistically. However, the effect of cyclosporine was thought to be more effective. The pain of the lesions was significantly decreased by cyclosporine but not by steroid. The decrease of burning sensation was more dependants upon steroid than cyclosporine, but no statistical relationship could be found. There were no clinical side effects. There was limitation to draw in conclusion due to small pool of this study group. But with the results, this suggestion could be proposed that either drug might be superior to another in effectivity in a specific lesion type or patient symptom, so selection and usage of one drug in a specific case could be better than universal application of one drug in all cases.

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관련 논문AI추천

Factors Affecting the Result of Intralesional Corticosteroid Injection in Patients With Oral Lichen Planus박정민, 은영규, 이영찬, 이준석, 정아라대한이비인후과학회 · Clinical and Experimental Otorhinolaryngology2018 · 제11권 제3호구강 편평태선에서 Elafin의 발현이상신, 이석근대한병리학회 · Journal of Pathology and Translational Medicine2004 · 제38권 제1호Comparison of Low-Level Laser Therapy versus Ozone Therapy in the Treatment of Oral Lichen PlanusHakki Oguz Kazancioglu, Merve Erisen대한피부과학회 · Annals of Dermatology2015 · 제27권 제5호Factors affecting treatment outcomes in patients with oral lichen planus lesions: a retrospective study of 113 cases김소현, 박신영, 윤필영, 이효정, Sung-Beom Kim, Yong-Hoon Choi대한치주과학회 · Journal of Periodontal & Implant Science2018 · 제48권 제4호구강편평태선 환자에서 보조적 치주치료의 효과권은영, 이주연, 최점일대한턱관절교합학회 · 구강회복응용과학지2015 · 제31권 제2호구강작열감 증후군 환자의 임상적 특징 및 스테로이드 가글 치료의 예비결과강성욱, 김철호, 이진석, 정연훈, 조민정대한이비인후과학회 · 대한이비인후과학회지 두경부외과학2004 · 제47권 제6호

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