Effects of fibrin glue on bone formation in combination with deproteinized bone xenografts in humans
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Thirty-six sinus grafts were performed in 34 patients with an alveolar crest bone height in the posterior maxilla of 3 to 5 mm before grafting. The sinuses were grafted using Bio-Oss alone or mixed with fibrin glue. Group 1 was the control group and included 25 patients who received a xenograft mixed in saline. Group 2 comprised 9 patients who received a xenograft and fibrin glue. The study was further subdivided at the time of 9 months. This histologic study evaluated by hematoxylin-eosin (H&E) and histomorphometric analysis whether fibrin glue in combination with Bio-Oss enhances bone regeneration in sinus floor elevation in humans. The new bone formation was better in Group 2 than in Group 1, but the difference was not significant. The absorption of the graft material was faster in Group 2 than in Group 1, in the short term, but better in Group 1 over the long term, although the difference was not significant. Lamellar bone was formed earlier in Group 1 compared to Group 2, but the difference was not significant. Overall, the surgery site stabilized earlier with new bone formation in Group 2 than in Group 1, but the difference was not significant. Combining a fibrin sealant and Bio-Oss could lead to improved scaffolds for bone tissue engineering based on the synergistic effects of the biomaterials. Therefore, Bio-Oss or Bio-Oss plus Tisseel may be used depending on the situation.
Abstract
Thirty-six sinus grafts were performed in 34 patients with an alveolar crest bone height in the posterior maxilla of 3 to 5 mm before grafting. The sinuses were grafted using Bio-Oss alone or mixed with fibrin glue. Group 1 was the control group and included 25 patients who received a xenograft mixed in saline. Group 2 comprised 9 patients who received a xenograft and fibrin glue. The study was further subdivided at the time of 9 months. This histologic study evaluated by hematoxylin-eosin (H&E) and histomorphometric analysis whether fibrin glue in combination with Bio-Oss enhances bone regeneration in sinus floor elevation in humans. The new bone formation was better in Group 2 than in Group 1, but the difference was not significant. The absorption of the graft material was faster in Group 2 than in Group 1, in the short term, but better in Group 1 over the long term, although the difference was not significant. Lamellar bone was formed earlier in Group 1 compared to Group 2, but the difference was not significant. Overall, the surgery site stabilized earlier with new bone formation in Group 2 than in Group 1, but the difference was not significant. Combining a fibrin sealant and Bio-Oss could lead to improved scaffolds for bone tissue engineering based on the synergistic effects of the biomaterials. Therefore, Bio-Oss or Bio-Oss plus Tisseel may be used depending on the situation.
참고문헌 (30)
- Cordaro L, "Bilateral simultaneous augmentation of the maxillary sinus floor with particulated mandible. Report of a technique and preliminary results", Clin Oral Implants Res, 14, pp.201~206 (2003)
- Boyne PJ, "Grafting of the maxillary sinus floor with autogenous marrow and bone", J Oral Surg, 38, pp.613~616 (1980)
- Jeong TY, "Histologic study of sinus grafting with Bio-Oss for implant placement", Hosp Dent (Tokyo), 17, pp.87~92 (2005)
- Pinholt EM, "Alveolar ridge augmentation in rats by Bio-Oss", Scand J Dent Res, 99, pp.154~161 (1991)
- Jensen SS, "Tissue reaction and material characteristics of four bone substitutes", Int J Oral Maxillofac Implants, 11, pp.55~56 (1996)
- Valentini P, "Maxillary sinus floor elevation for implant placement with demineralized freeze-dried bone and bovine bone (Bio-Oss): a clinical study of 20 patients", Int J Periodontics Restorative Dent, 17, pp.232~241 (1997)
- Hurzeler MB, "Reconstruction of the severely resorbed maxilla with dental implants in the augmented maxillary sinus: a 5-year clinical investigation", Int J Oral Maxillofac Implants, 11, pp.466~475 (1996)
- Hising P, "Reconstruction of severely resorbed alveolar ridge crests with dental implants using a bovine bone mineral for augmentation", Int J Oral Maxillofac Implants, 16, pp.90~97 (2001)
- Valentini P, "Histological evaluation of Bio-Oss in a 2-stage sinus floor elevation and implantation procedure. A human case report", Clin Oral Implants Res, 9, pp.59~64 (1998)
- Sanchez AR, "Influence of platelet-rich plasma added to xenogeneic bone grafts in periimplant defects: a vital fluorescence study in dogs", Clin Implant Dent Relat Res, 7, pp.61~69 (2005)
- Marx RE, "Platelet-rich plasma: Growth factor enhancement for bone grafts", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 85, pp.638~646 (1998)
- Niedhart C, "Stimulation of bone formation with an in situ setting tricalcium phosphate", rhBMP-2 composite in rats, 2003, pp.65, 17~23
- Stefani CM, "Platelet-derived growth factor", insulin-like growth factor-1 combination and bone regeneration around implants placed into extraction sockets: a histometric study in dogs, 2000, pp.9, 126~131
- Tayapongsak P, "Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow", J Oral Maxillofac Surg, 52, pp.161~165 (1994)
- Matras H, "Fibrin seal: the state of the art", J Oral Maxillofac Surg, 43, pp.605~611 (1985)
- Diamond MP, "Effect of Tisseel on expression of tissue plasminogen activator and plasminogen activator inhibitor-1", Fertil Steril, 81, pp.1657~1664 (2004)
- Yamada Y, "Bone regeneration following injection of mesenchymal stem cells and fibrin glue with a biodegradable scaffold", J Craniomaxillofac Surg, 31, pp.27~33 (2003)
- Keller J, "Fixation of osteochondral fractures. Fibrin sealant tested in dogs", Acta Orthop Scand, 56, pp.323~326 (1985)
- Marktl W, "The effect of factor XIII on wound granulation in the rat", Thromb Diath Haemorrh, 32, pp.578~581 (1974)
- Choukroun J, "Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part V: histologic evaluations of PRF effects on bone allograft maturation in sinus lift", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101, pp.299~303 (2006)
- Wittkampf AR, "Fibrin glue as cement for HA-granules", J Craniomaxillofac Surg, 17, pp.179~181 (1989)
- Nakamura K, "Osteogenic response of the rabbit femur to a hydroxyapatite thermal decomposition product-fibrin glue mixture", Biomaterials, 19, pp.1901~1907 (1998)
- von Arx T, "Lateral ridge augmentation using different bone fillers and barrier membrane application. A histologic and histomorphometric pilot study in the canine mandible", Clin Oral Implants Res, 12, pp.260~269 (2001)
- Kim MJ, "Various bone grafting materials in the dental surgery" (2004), Narae Publishing Inc
- Piattelli M, "Bone reactions to anorganic bovine bone (Bio-Oss) used in sinus augmentation procedures: a histologic long-term report of 20 cases in humans", Int J Oral Maxillofac Implants, 14, pp.835~840 (1999)
- Ohazama A, "Periodontal tissue regeneration using fibrin tissue adhesive material in vitro and in vivo", Periodontal Clin Invest, 18, pp.26~38 (1996)
- Bosch P, "Experimental investigations of the effect of the fibrin adhesive on the Kiel heterologous bone graft", Arch Orthop Trauma Surg, 96, pp.177~185 (1980)
- Thorn JJ, "Autologous fibrin glue with growth factors in reconstructive maxillofacial surgery", Int J Oral Maxillofac Surg, 33, pp.95~100 (2004)
- Kawamura M, "Human fibrin is a physiologic delivery system for bone morphogenetic protein", Clin Orthop Relat Res, 235, pp.302~310 (1988)
- Warrer K, "Effect of Tisseel on healing after periodontal flap surgery", J Clin Periodontol, 19, pp.449~454 (1992)