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Platelet rich fibrin in the management of established dry socket

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Objectives: Dry socket may occur secondary to the removal of any tooth. However, most dry socket cases develop in the third molar region. Dry socket is multifactorial in nature and has been treated using various modalities with varying success rates. This study assessed the efficacy of platelet rich fibrin (PRF) in established dry socket. Materials and Methods: Ten patients of either sex aged from 41 to 64 years with established dry socket according to established criteria were treated using PRF. Evaluation was performed by observing the reduction of pain using visual analogue scale, analgesic tablet use over the follow-up period, and healing parameters.Results: Pain was reduced on the first day in all patients with decreased analgesic use. Pain was drastically reduced during follow-up on the first, second, third, and seventh days with a fall in pain score of 0 to 1 after the first day alone. The pain scores of all patients decreased to 1 by the first day except in one patient, and the scores decreased to 0 in all patients after 48 hours. Total analgesic intake ranged from 2 to 6 tablets (aceclofenac 100 mg per tablet) over the follow-up period of 7 days. Healing was satisfactory in all patients by the end of the seventh day. Conclusion: PRF showed early pain reduction in established dry socket with minimal analgesic intake. No patients had allergic reactions to PRF as it is derived from the patient’s own blood. PRF showed good wound healing. Our study suggests that PRF should be considered as a treatment modality for established dry socket.

Abstract

Objectives: Dry socket may occur secondary to the removal of any tooth. However, most dry socket cases develop in the third molar region. Dry socket is multifactorial in nature and has been treated using various modalities with varying success rates. This study assessed the efficacy of platelet rich fibrin (PRF) in established dry socket. Materials and Methods: Ten patients of either sex aged from 41 to 64 years with established dry socket according to established criteria were treated using PRF. Evaluation was performed by observing the reduction of pain using visual analogue scale, analgesic tablet use over the follow-up period, and healing parameters.Results: Pain was reduced on the first day in all patients with decreased analgesic use. Pain was drastically reduced during follow-up on the first, second, third, and seventh days with a fall in pain score of 0 to 1 after the first day alone. The pain scores of all patients decreased to 1 by the first day except in one patient, and the scores decreased to 0 in all patients after 48 hours. Total analgesic intake ranged from 2 to 6 tablets (aceclofenac 100 mg per tablet) over the follow-up period of 7 days. Healing was satisfactory in all patients by the end of the seventh day. Conclusion: PRF showed early pain reduction in established dry socket with minimal analgesic intake. No patients had allergic reactions to PRF as it is derived from the patient’s own blood. PRF showed good wound healing. Our study suggests that PRF should be considered as a treatment modality for established dry socket.

참고문헌 (36)

  1. Daly B, "Local interventions for the management of alveolar osteitis (dry socket)", Cochrane Database Syst Rev, 12 (2012)
  2. Fridrich KL, "Alveolar osteitis following surgical removal of mandibular third molars", Anesth Prog, 37, pp.32~41 (1990)
  3. Blum IR, "Contemporary views on dry socket (alveolar osteitis): a clinical appraisal of standardization, aetiopathogenesis and management:a critical review", Int J Oral Maxillofac Surg, 31, pp.309~317 (2002)
  4. Vezeau PJ, "Dental extraction wound management: medicating postextraction sockets", J Oral Maxillofac Surg, 58, pp.531~537 (2000)
  5. Caso A, "Prevention of alveolar osteitis with chlorhexidine: a meta-analytic review", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 99, pp.155~159 (2005)
  6. Garcia AG, "Does oral contraceptive use affect the incidence of complications after extraction of a mandibular third molar?", Br Dent J, 194, pp.453~455 (2003)
  7. Muhonen A, "Factors predisposing to postoperative complications related to wisdom tooth surgery among university students", J Am Coll Health, 46, pp.39~42 (1997)
  8. Noroozi AR, "Modern concepts in understanding and management of the "dry socket" syndrome: comprehensive review of the literature", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 107, pp.30~35 (2009)
  9. Bloomer CR, "Straws do not cause dry sockets when third molars are extracted", Tex Dent J, 129, pp.25~32 (2012)
  10. Reekie D, "The prevention of 'dry socket' with topical metronidazole in general dental practice", Br Dent J, 200, pp.210~213 (2006)
  11. Kaya GŞ, "Comparison of alvogyl, SaliCept patch, and low-level laser therapy in the management of alveolar osteitis", J Oral Maxillofac Surg, 69, pp.1571~1577 (2011)
  12. Jovanović G, "Assessment of the effectiveness of low level laser in the treatment of alveolar osteitis", Vojnosanit Pregl, 68, pp.506~510 (2011)
  13. Pal US, "Comparative evaluation of zinc oxide eugenol versus gelatin sponge soaked in plasma rich in growth factor in the treatment of dry socket: an initial study", Contemp Clin Dent, 4, pp.37~41 (2013)
  14. Haraji A, "Effect of plasma rich in growth factors on alveolar osteitis", Natl J Maxillofac Surg, 3, pp.38~41 (2012)
  15. Singh V, "Honey a sweet approach to alveolar osteitis: a study", Natl J Maxillofac Surg, 5, pp.31~34 (2014)
  16. Martínez-Zapata MJ, "Efficacy and safety of the use of autologous plasma rich in platelets for tissue regeneration: a systematic review", Transfusion, 49, pp.44~56 (2009)
  17. Anitua E, "Use of PRGF to accelerate bone and soft tissue regeneration in postextraction sites", Implant Dialogue, 36, pp.3~14 (2003)
  18. Alexander RE, "Dental extraction wound management: a case against medicating postextraction sockets", J Oral Maxillofac Surg, 58, pp.538~551 (2000)
  19. Plachokova AS, "Effect of platelet-rich plasma on bone regeneration in dentistry: a systematic review", Clin Oral Implants Res, 19, pp.539~545 (2008)
  20. Aldecoa EA, "A mew approach to bone regeneration:plasma rich in growth factors", pp.172~ (2001), Puesta al Dia Publicaciones
  21. Sammartino G, "Use of autologous platelet-rich plasma (PRP) in periodontal defect treatment after extraction of impacted mandibular third molars", J Oral Maxillofac Surg, 63, pp.766~770 (2005)
  22. Simon D, "Potential for osseous regeneration of platelet-rich plasma--a comparative study in mandibular third molar sockets", Indian J Dent Res, 15, pp.133~136 (2004)
  23. Mozzati M, "The impact of plasma rich in growth factors on clinical and biological factors involved in healing processes after third molar extraction", J Biomed Mater Res A, 95, pp.741~746 (2010)
  24. Rutkowski JL, "Platelet rich plasma to facilitate wound healing following tooth extraction", J Oral Implantol, 36, pp.11~23 (2010)
  25. 송지영, "가토의 두개 결손부에서의 실크 단백질과 platelet-rich fibrin (PRF)의 골형성 효과", 대한구강악안면외과학회지, 36(4), pp.250~254 (2010), 대한구강악안면외과학회
  26. Halberstein RA, "Clinical management and control of alveolalgia ("dry socket") with vitamin C", Am J Dent, 16, pp.152~154 (2003)
  27. Burgoyne CC, "The efficacy of a topical anesthetic gel in the relief of pain associated with localized alveolar osteitis", J Oral Maxillofac Surg, 68, pp.144~148 (2010)
  28. Faizel S, "Comparision between neocone, alvogyl and zinc oxide eugenol packing for the treatment of dry socket: a double blind randomised control trial", J Maxillofac Oral Surg, 14, pp.312~320 (2015)
  29. Rani A, "Comparative evaluation of Er:Cr:YSGG, diode laser and alvogyl in the management of alveolar osteitis: a prospective randomized clinical study", J Maxillofac Oral Surg, 15, pp.349~354 (2016)
  30. Haghighat A, "The effectiveness of GECB pastille in reducing complications of dry socket syndrome", Int J Dent, 2012, pp.587461~ (2012)
  31. Taberner-Vallverdú M, "Efficacy of different methods used for dry socket management:a systematic review", Med Oral Patol Oral Cir Bucal, 20, pp.e633~e639 (2015)
  32. Kolokythas A, "Alveolar osteitis: a comprehensive review of concepts and controversies", Int J Dent, 2010, pp.249073~ (2010)
  33. Sharif MO, "Interventions for the prevention of dry socket: an evidence-based update", Br Dent J, 217, pp.27~30 (2014)
  34. Torres-Lagares D, "Update on dry socket: a review of the literature", Med Oral Patol Oral Cir Bucal, 10, pp.81~85 (2005)
  35. Fazakerley M, "Dry socket: a painful post-extraction complication (a review)", Dent Update, 18, pp.31~34 (1991)
  36. Cardoso CL, "Clinical concepts of dry socket", J Oral Maxillofac Surg, 68, pp.1922~1932 (2010)

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