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칼슘과 비타민D 섭취가 티타늄 임플랜트 주위의 골 형성에 미치는 영향

On bone formation around titanium implant

이재열|신상훈|김용덕|정인교|김규천|황대석|김욱규|박광일
대한구강악안면외과학회 (Korean Association Of Oral And Maxillofacial Surgeons)|2007.04|대한구강악안면외과학회지 (Journal of the Korean Association of Oral and Maxillofacial Surgeons)|제33권 제2호|pp. 131-138

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참고문헌

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초록

Abstract

The purpose of this study was to observe the effect of calcium and vitamin D to the titanium implant osseointegration in animal model. 32 rats, 10 weeks of age, were divided into two group: additional calcium and vitamin D supplementation group and a control group. Titanium screw implant(diameter, 2.0mm; length, 3.5mm; pitch-height 0.4 ㎜) were placed into tibia of 32 rats, 16 in the control group and 16 in the experimental group. The rats were sacrificed at different time interval(1, 2, 4, and 8 weeks after implantation) for histopathologic observation, histomorphometric analysis and immunohistochemistry with osteocalcin and osteopontin antibody. Histopathologically findings, newly formed bone was seen at 1 weeks and became lamellar bone at 2 weeks, and mature trabecullar bone was seen at 4 weeks experimental group. In control group, thickness of regenerated bone increased till 4 weeks gradually and trabecullar bone was seen at 8 weeks. By histomorphometric analysis, bone marrow density was increased significantly at 1 and 2 weeks in experimental group compared to control group. Osteocalcin immunoreactivity was strong at 1 week experimental group and reduced after 4 weeks gradually. But it was continuously weakly from 1 to 4 weeks in control group. Osteopontin immunoreactivity was very strong in newly formed bone from 2 to 8 weeks experimental group. And the amount of osteopontin expression was more abundant in experimental group. The results of this study suggest that calcium and vitamin D supplementation promotes bone healing around dental implants

참고문헌 (20)

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관련 논문AI추천

골다공증 유도 흰쥐에서 칼슘과 비타민 D 섭취가 티타늄 임플랜트 주위의 골 형성에 미치는 영향김규천, 김용덕, 김욱규, 신상훈, 이재열, 정석영, 정인교대한구강악안면외과학회 · 대한구강악안면외과학회지2008 · 제34권 제3호천공형 티타늄막과 탈회동결건조골의 신생골 형성에 대한 영향허익, 권영혁, 김종관, 박준봉, 이윤호대한치주과학회 · Journal of Periodontal & Implant Science2004 · 제34권 제1호전기자극이 성견 골결손부에 매식된 임플란트 주위조직의 치유에 미치는 영향김영준, 김옥수, 심재창, 정현주대한치주과학회 · Journal of Periodontal & Implant Science2004 · 제34권 제1호임플란트 표면처리에 따른 골융합의 차이허익, 권영혁, 박준봉, 황하준대한치주과학회 · Journal of Periodontal & Implant Science2004 · 제34권 제4호임프란트 식립시 이식된 탈회골기질을 함유한 이식재의 골형성에 대한 연구권용대, 김여갑, 류동목, 오정환, 윤병욱, 이백수대한구강악안면외과학회 · 대한구강악안면외과학회지2005 · 제31권 제6호개 모델에서의 임플란트 주위 골결손시 Ca-P 표면 처리된 이종골의 효과이선경, 이승호, 이준영, 전혜란, 조수연, 한근아대한치주과학회 · Journal of Periodontal & Implant Science2006 · 제36권 제4호

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