이하선부에 발생한 Kimura’s disease에 대한 치험례
A case report of Kimura’s disease in the parotid region
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■이하선부에 발생한 Kimura’s disease에 대한 치험례 …변성수.정휘동.최영달.김현실.차인호.김형준…554 ■A case report of Kimura’s disease in the parotid region 이하선부에 발생한 Kimura’s disease에 대한 치험례 변성수1.정휘동1.최영달1.김현실2,4.차인호1,3,4.김형준1,3,4 1연세대학교 치과대학 구강악안면외과학교실, 2구강병리학교실, 3구강과학연구소, 4구강종양연구소 Abstract (J. Kor. Oral Maxillofac. Surg. 2007;33:554-558) A CASE REPORT OF KIMURA’S DISEASE IN THE PAROTID REGION Sung-Soo Byun1, Hwui-Dong Jung1, Young-Dal Choi1, Hyun-Sil Kim2,4, In-Ho Cha1,3,4, Hyung Jun Kim1,3,4 1Department of Oral and Maxillofacial Surgery, 2Department of Oral Pathology, 3Oral Science Research Center, 4Oral Cancer Research Institute, College of Dentistry, Yonsei University, Seoul, Korea Kimura’s disease is a chronic inflammatory disorder presenting regional lymphadenopathy with painless soft tissue mass. Clinically, peripheral eosinophilia and elevated serum IgE levels are observed, and proteinuria associated with renal disease can also be present. Although its etiology is not clearly understood, it occurs predominantly in young Asian males and presents as a deep, subcutaneous mass involving salivary glands of the preauricular and submandibular regions. Spontaneous remission is very rare, and although treatments such as steroid, cytotoxic therapy and irradiation are available, chronic recurrence is very common. As such, surgical excision is regarded as the mainstay of therapy for localized lesions. Histopathologically, Kimura’s disease features eosinophilic abscsesses and dense lymphoid aggregates with germinal center. Clinical differential diagnosis of Kimura’s disease from other parotid diseases with accompanying lymphadenopathy is often very challenging prior to biopsy. The authors report a case of a 19-year-old male diagnosed with Kimura’s disease in the parotid region who underwent surgical excision and was followed up for 6 years, along with a review of related literature.
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