A Fatal Case of a Large Abdominal Wall Muscle Hematoma Secondary to Low-Molecular-Weight Heparin Injections
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
The use of low-molecular-weight heparin (LMWH) can lead to major life threatening complications, including hematomas. Abdominal wall muscle hematomas are rarely fatal, and encompass a wide spectrum of severity depending on size, etiology, and associated complications; but because of their rarity may be misdiagnosed clinically. We report a fatal case of an 80-year-old female who received LMWH after an episode of pulmonary thromboembolism and was subsequently diagnosed with a large right abdominal wall hematoma complicated with hypovolemic shock and acute kidney injury.
Abstract
The use of low-molecular-weight heparin (LMWH) can lead to major life threatening complications, including hematomas. Abdominal wall muscle hematomas are rarely fatal, and encompass a wide spectrum of severity depending on size, etiology, and associated complications; but because of their rarity may be misdiagnosed clinically. We report a fatal case of an 80-year-old female who received LMWH after an episode of pulmonary thromboembolism and was subsequently diagnosed with a large right abdominal wall hematoma complicated with hypovolemic shock and acute kidney injury.
참고문헌 (14)
- Kayrak M, "Is enoxaparin injection from the abdominal wall safe in elderly people?: a fatal case of rectus sheath hematoma", Can Fam Physician, 54, pp.1246~1248 (2008)
- Agnelli G, "Enoxaparin plus compression stockings compared with compression stockings alone in the prevention of venous thromboembolism after elective neurosurgery", N Engl J Med, 339, pp.80~85 (1998)
- Weitz JI, "Low-molecular-weight heparins", N Engl J Med, 337, pp.688~698 (1997)
- Albertsen IE, "Prevention of venous thromboembolism with new oral anticoagulants versus standard pharmacological treatment in acute medically ill patients: a systematic review and metaanalysis", Drugs, 72, pp.1755~1764 (2012)
- Nourbakhsh E, "Abdominal wall hematoma associated with low-molecular-weight heparins: an important complication in older adults", J Am Geriatr Soc, 59, pp.1543~1545 (2011)
- Barna L, "Rectus sheath hematoma following exercise testing: a case report", J Med Case Rep, 3, pp.9000~ (2009)
- Valdez G, "Clinical images: Spontaneous rectus sheath hematoma", CMAJ, 182, pp.E20~ (2010)
- Choi DH, "Low-molecular-weight heparin associated intramuscular hematoma with compartment syndrome", Korean J Intern Med, 69, pp.S948~S951 (2005)
- Miyauchi T, "Rectus sheath hematoma in an elderly woman under anti-coagulant therapy", J Med Invest, 48, pp.216~220 (2001)
- Donaldson J, "Rectus sheath hematoma associated with low-molecular-weight heparin: a case series", Ann R Coll Surg Engl, 89, pp.309~312 (2007)
- Garcia DA, "American College of Chest Physicians: Parenteral anticoagulants: antithrombotic therapy and prevention of thrombosis, 9th ed:American college of chest physicians evidence-based clinical practice guidelines", Chest, 141(2 Suppl), pp.e24S~e43S (2012)
- Chuang YJ, "Heparin enhances the specificity of antithrombin for thrombin and factor Xa independent of the reactive center loop sequence. Evidence for an exosite determinant of factor Xa specificity in heparin-activated antithrombin", J Bio Chem, 276, pp.14961~14971 (2001)
- Krishnan JA, "Treatment of venous thromboembolism with low-molecular-weight heparin: a synthesis of the evidence published in systematic literature reviews", Respir Med, 98, pp.376~386 (2004)
- Tatro DS, "Drug interaction facts 2013: the authority on drug interactions", Lippincott Williams & Wilkins, pp.937~ (2012)