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중환자실에서 Tigecycline과 Amikacin의 병합 치료 후 호전된 광범위약제내성 Acinetobacter baumannii 폐렴 1예

Extreme Drug Resistant Acinetobacter Nosocomial Ventilator-Associated Pneumonia Treated Successfully with Tigecycline and Amikacin in Intensive Care Unit

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초록

Infections due to multidrug resistant Acinetobacter baumannii have become a challenging problem in intensive care units. Tigecycline is a derivative of minocyline, and has provided new hope for the treatment of multidrug-resistant A. baumannii infections. Because isolates showing reduced susceptibility to minocycline or tigecycline have emerged in many countries, empirical combination therapy has become common practice to treat patients infected with extreme drug-resistant A. baumannii. Herein we report a case of extreme drug-resistant A. baumannii infection successfully treated with tigecycline and amikacin.

Abstract

Infections due to multidrug resistant Acinetobacter baumannii have become a challenging problem in intensive care units. Tigecycline is a derivative of minocyline, and has provided new hope for the treatment of multidrug-resistant A. baumannii infections. Because isolates showing reduced susceptibility to minocycline or tigecycline have emerged in many countries, empirical combination therapy has become common practice to treat patients infected with extreme drug-resistant A. baumannii. Herein we report a case of extreme drug-resistant A. baumannii infection successfully treated with tigecycline and amikacin.

참고문헌 (20)

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관련 논문AI추천

다제내성 Acinetobacter baumannii균에서 Tigecycline과 Colistin 치료 후의 임상 결과 평가최인, 김혜미, 박선희, 최은주한국병원약사회 · 병원약사회지2016 · 제33권 제3호다약제내성 균주 감염에 대한 Tigecycline의 치료강성훈, 권기태, 배상수, 서아영, 송도영, 오대명, 윤경화, 이미정, 이신원, 정동형, 황병식영남대학교 의과대학 · Journal of Yeungnam Medical Science2011 · 제28권 제2호균혈증이 동반된 중증 지역사회 획득 Acinetobacter baumannii 폐렴 1예강보형, 김유재, 안지현, 윤신교, 이유미, 이호수, 최상호, 홍상범대한감염학회 · Infection and Chemotherapy2012 · 제44권 제2호중환자의 카바페넴 내성 Acinetobacter baumannii 폐렴 치료 시 발생한 이상사례와 위험 인자배성권, 배성진, 이용수, 최인아한국병원약사회 · 병원약사회지2019 · 제36권 제4호A Case of Community-Acquired Pneumonia Caused by Multidrug-Resistant Acinetobacter baumannii in Korea구남수, 김준명, 손영웅, 송영구, 안미영, 안진영, 안혜원, 전용덕, 정인영, 최준용, 한상훈대한감염학회 · Infection and Chemotherapy2017 · 제49권 제4호다제내성 Acinetobacter baumannii 또는 Pseudomonas aeruginosa에 의한 폐렴에서 Colistin 정맥주입과 분무요법의 치료 효과 및 안전성 비교안서현, 안혜림, 이수진, 황보신이한국병원약사회 · 병원약사회지2020 · 제37권 제1호

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