Histopathology and ultrastructural findings of pediatric sialolithiasis: a brief communication
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Sialolithiasis is a condition in which the salivary gland excretory duct is obstructed due to the formation of calcareous deposits and is uncommon in children compared to adults. The treatment modalities range from a conservative approach involving hydration to a surgical approach. Though several studies have analyzed the sialolith micromorphology structures, studies on pediatric sialoliths remain scarce. This brief communication aims to describe the sialolith micromorphology to understand the mechanism of mineralization and growth of pediatric sialoliths. A 6-year-old Korean female presented with swelling under her tongue. The intraoral examination revealed a painless yellowish hard mass beneath the tongue near the Wharton’s duct which was suspected as a sialolith. After receiving the informed consent, the sialolithotomy was performed under local anesthesia. The obtained stone was analyzed through histopathology and transmission electron microscope examinations to understand the mechanism of mineralization and growth of pediatric sialolith. The micromorphology and growth processes of pediatric sialolith remain undescribed. More comprehensive microscopic studies are needed regarding their distinctive characteristics. By expanding knowledge about sialoliths micromorphology, development of new preventive, diagnostic and patient-tailored treatment methods of pediatric sialolithiasis will be enhanced.
Abstract
Sialolithiasis is a condition in which the salivary gland excretory duct is obstructed due to the formation of calcareous deposits and is uncommon in children compared to adults. The treatment modalities range from a conservative approach involving hydration to a surgical approach. Though several studies have analyzed the sialolith micromorphology structures, studies on pediatric sialoliths remain scarce. This brief communication aims to describe the sialolith micromorphology to understand the mechanism of mineralization and growth of pediatric sialoliths. A 6-year-old Korean female presented with swelling under her tongue. The intraoral examination revealed a painless yellowish hard mass beneath the tongue near the Wharton’s duct which was suspected as a sialolith. After receiving the informed consent, the sialolithotomy was performed under local anesthesia. The obtained stone was analyzed through histopathology and transmission electron microscope examinations to understand the mechanism of mineralization and growth of pediatric sialolith. The micromorphology and growth processes of pediatric sialolith remain undescribed. More comprehensive microscopic studies are needed regarding their distinctive characteristics. By expanding knowledge about sialoliths micromorphology, development of new preventive, diagnostic and patient-tailored treatment methods of pediatric sialolithiasis will be enhanced.
참고문헌 (15)
- Thong HK, "Recurrent submandibular sialolithiasis in a child", Cureus, 12, pp.e12163~ (2020)[DOI]
- Francis CL, "Pediatric sialadenitis", Otolaryngol Clin North Am, 47, pp.763~778 (2014)[DOI]
- 박수영, "Sialolithiasis in children: Three case reports", Oral Biology Research, 43(4), pp.340~348 (2019), 치의학연구원[DOI]
- Karengera D, "Sialolithiasis in children as a diagnostic dilemma", Eur Arch Otorhinolaryngol, 257, pp.161~163 (2000)[DOI]
- Inui A, "Comparison of sialolithiasis in pediatric and adult patients", Oral Sci Int, 14, pp.37~39 (2017)[DOI]
- Nolasco P, "Structure and growth of sialoliths : computed microtomography and electron microscopy investigation of 30 specimens", Microsc Microanal, 19, pp.1190~1203 (2013)[DOI]
- Alcure ML, "Clinical and histopathological findings of sialoliths", Braz J Oral Sci, 4, pp.899~903 (2005)
- De-Castro ICV, "Clinicopathological study of sialolithiasis : a retrospective analysis of 11 cases", J Oral Diagn, 04, pp.e20190006~ (2019)
- Busso CS, "A comprehensive analysis of sialolith proteins and the clinical implications", Clin Proteomics, 17, pp.12~ (2020)[DOI]
- Tretiakow D, "Classification of submandibular salivary stones based on ultrastructural studies", Oral Dis, 27, pp.1711~1719 (2021)[DOI]
- Im YG, "Characterization of a submandibular gland sialolith : micromorphology, crystalline structure, and chemical compositions", Oral Surg Oral Med Oral Pathol Oral Radiol, 124, pp.e13~e20 (2017)[DOI]
- 이효설, "소아의 구강저에 발생한 타석증", 대한소아치과학회지, 36(1), pp.114~118 (2009), 대한소아치과학회
- Hayashibara T, "Salivary calculi in children : a study using an energy dispersive X-ray analyzer and contact microradiography", Pediatr Dent J, 14, pp.41~45 (2004)[DOI]
- Kasaboğlu O, "Micromorphology of sialoliths in submandibular salivary gland : a scanning electron microscope and X-ray diffraction analysis", J Oral Maxillofac Surg, 62, pp.1253~1258 (2004)[DOI]
- Alves de Matos AP, "On the structural diversity of sialoliths", Microsc Microanal, 13, pp.390~396 (2007)[DOI]