Outcomes of patients with COVID-19 requiring extracorporeal membrane oxygenation and continuous renal replacement therapy in the United States
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background: Coronavirus disease 2019 (COVID-19) infection is associated with significant morbidity and mortality. Some patients develop severe acute respiratory distress syndrome and kidney failure requiring the combination of extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). Methods: Retrospective cohort study of 127 consecutive patients requiring combined ECMO and CRRT support in intensive care units at an ECMO center in Marietta, GA, United States. Results: Sixty and 67 patients with and without COVID-19, respectively, required ECMO-CRRT support. After adjusting for confounding variables, patients with COVID-19 had increased mortality at 30 days (hazard ratio [HR], 5.19; 95% confidence interval [CI], 2.51–10.7; P<0.001) and 90 days (HR, 6.23; 95% CI, 2.60–14.9; P<0.001). Conclusions: In this retrospective study, patients with COVID-19 who required ECMO-CRRT had increased mortality when compared to patients without COVID-19.
Abstract
Background: Coronavirus disease 2019 (COVID-19) infection is associated with significant morbidity and mortality. Some patients develop severe acute respiratory distress syndrome and kidney failure requiring the combination of extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). Methods: Retrospective cohort study of 127 consecutive patients requiring combined ECMO and CRRT support in intensive care units at an ECMO center in Marietta, GA, United States. Results: Sixty and 67 patients with and without COVID-19, respectively, required ECMO-CRRT support. After adjusting for confounding variables, patients with COVID-19 had increased mortality at 30 days (hazard ratio [HR], 5.19; 95% confidence interval [CI], 2.51–10.7; P<0.001) and 90 days (HR, 6.23; 95% CI, 2.60–14.9; P<0.001). Conclusions: In this retrospective study, patients with COVID-19 who required ECMO-CRRT had increased mortality when compared to patients without COVID-19.
참고문헌 (28)
- Shih E, "Outcomes of extracorporeal membrane oxygenation in patients with severe acute respiratory distress syndrome caused by COVID-19 versus influenza", Ann Thorac Surg, 113, pp.1445~1451 (2022)
- Cau A, "Acute kidney injury and renal replacement therapy in COVID-19 versus other respiratory viruses : a systematic review and meta-analysis", Can J Kidney Health Dis, 8, pp.20543581211052185~ (2021)
- Metnitz PG, "Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients", Crit Care Med, 30, pp.2051~2058 (2002)
- ARDS Definition Task Force, "Acute respiratory distress syndrome : the Berlin definition", JAMA, 307, pp.2526~2533 (2012)
- El Mouhayyar C, "Factors associated with severity of acute kidney injury and adverse outcomes in critically ill patients with COVID-19", Nephron, 146, pp.584~592 (2022)
- Silver SA, "The prevalence of acute kidney injury in patients hospitalized with COVID-19 infection : a systematic review and meta-analysis", Kidney Med, 3, pp.83~98 (2021)
- Burke E, "Outcomes of renal replacement therapy in the critically ill with COVID-19", Med Intensiva, 45, pp.325~331 (2021)
- Zhou P, "Addendum : a pneumonia outbreak associated with a new coronavirus of probable bat origin", Nature, 588, pp.E6~ (2020)
- Naicker S, "The novel coronavirus 2019 epidemic and kidneys", Kidney Int, 97, pp.824~828 (2020)
- Sabaghian T, "COVID-19 and acute kidney injury : a systematic review", Front Med(Lausanne), 9, pp.705908~ (2022)
- Thongprayoon C, "Incidence and impact of acute kidney injury in patients receiving extracorporeal membrane oxygenation : a meta-analysis", J Clin Med, 8, pp.981~ (2019)
- Lumlertgul N, "Long-term outcomes in patients who received veno-venous extracorporeal membrane oxygenation and renal replacement therapy : a retrospective cohort study", Ann Intensive Care, 12, pp.70~ (2022)
- Fleming GM, "A multicenter international survey of renal supportive therapy during ECMO : the Kidney Intervention During Extracorporeal Membrane Oxygenation(KIDMO)group", ASAIO J, 58, pp.407~414 (2012)
- Kielstein JT, "Renal function and survival in 200 patients undergoing ECMO therapy", Nephrol Dial Transplant, 28, pp.86~90 (2013)
- Al-Fares A, "Extracorporeal life support and systemic inflammation", Intensive Care Med Exp, 7(Suppl 1), pp.46~ (2019)
- Borasino S, "Impact of hemolysis on acute kidney injury and mortality in children supported with cardiac extracorporeal membrane oxygenation", J Extra Corpor Technol, 50, pp.217~224 (2018)
- Kilburn DJ, "The complex relationship of extracorporeal membrane oxygenation and acute kidney injury : causation or association?", Biomed Res Int, 2016, pp.1094296~ (2016)
- Ling RR, "Evolving outcomes of extracorporeal membrane oxygenation during the first 2 years of the COVID-19 pandemic : a systematic review and meta-analysis", Crit Care, 26, pp.147~ (2022)
- Diaz J, "Use of synchronous kidney and lung extracorporeal support for severe COVID-19 : a single-center retrospective study", Clin Nephrol, 98, pp.182~187 (2022)
- Bertini P, "ECMO in COVID-19 patients : a systematic review and meta-analysis", J Cardiothorac Vasc Anesth, 36(8 Pt A), pp.2700~2706 (2022)
- Fanelli V, "Extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome : a multicenter retrospective cohort study", Crit Care, 26, pp.34~ (2022)
- Brown JR, "Duration of acute kidney injury impacts long-term survival after cardiac surgery", Ann Thorac Surg, 90, pp.1142~1148 (2010)
- Distelmaier K, "Duration of extracorporeal membrane oxygenation support and survival in cardiovascular surgery patients", J Thorac Cardiovasc Surg, 155, pp.2471~2476 (2018)
- Singbartl K, "Kidney-immune system crosstalk in AKI", Semin Nephrol, 39, pp.96~106 (2019)
- Woodrow G, "Cause of death in acute renal failure", Nephrol Dial Transplant, 7, pp.230~234 (1992)
- Odutayo A, "AKI and long-term risk for cardiovascular events and mortality", J Am Soc Nephrol, 28, pp.377~387 (2017)
- Thomas JM, "Adjunct use of continuous renal replacement therapy with extracorporeal membrane oxygenation achieves negative fluid balance and enhances oxygenation which improves survival in critically ill patients without kidney failure", Blood Purif, 51, pp.477~484 (2022)
- Hadadi A, "Long-term impact of the COVID-19 associated AKI : the relationship between kidney recovery and mortality in a 10-month follow-up cohort study", Kidney Blood Press Res, 47, pp.486~491 (2022)