Is conservative treatment (enucleation using modified Carnoy’s solution) of odontogenic keratocyst in the maxilla good prognosis?
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Odontogenic keratocysts (OKCs) located in the maxillae have rarely been reported in the literature. Standard treatment modalities for OKC range from marsupialization to marginal resection. However, most of the studies on OKC treatment have been related to mandibular OKCs. The anatomical structure and loose bone density of the maxillae and the empty space of the maxillary sinus could allow rapid growth of a lesion and the ability to tolerate tumor occupancy in the entire maxilla within a short period of time. Therefore, OKCs of the maxillae require more aggressive surgery, such as resection. As an alternative, this report introduces a modified Carnoy’s solution, a strong acid, as an adjuvant chemotherapy after cyst enucleation. This report describes the clinical outcomes of enucleation using a modified Carnoy’s solution in patients with large OKCs on the posterior maxillae. In three cases, application of a modified Carnoy’s solution had few side effects or morbidity. Each patient was followed for four to six years, and none showed any signs of recurrence. In conclusion, adjuvant treatment with a modified Carnoy’s solution can be considered a treatment option capable of reducing the recurrence rate of OKC in the maxillae.
Abstract
Odontogenic keratocysts (OKCs) located in the maxillae have rarely been reported in the literature. Standard treatment modalities for OKC range from marsupialization to marginal resection. However, most of the studies on OKC treatment have been related to mandibular OKCs. The anatomical structure and loose bone density of the maxillae and the empty space of the maxillary sinus could allow rapid growth of a lesion and the ability to tolerate tumor occupancy in the entire maxilla within a short period of time. Therefore, OKCs of the maxillae require more aggressive surgery, such as resection. As an alternative, this report introduces a modified Carnoy’s solution, a strong acid, as an adjuvant chemotherapy after cyst enucleation. This report describes the clinical outcomes of enucleation using a modified Carnoy’s solution in patients with large OKCs on the posterior maxillae. In three cases, application of a modified Carnoy’s solution had few side effects or morbidity. Each patient was followed for four to six years, and none showed any signs of recurrence. In conclusion, adjuvant treatment with a modified Carnoy’s solution can be considered a treatment option capable of reducing the recurrence rate of OKC in the maxillae.
참고문헌 (13)
- Maurette PE, "Conservative treatment protocol of odontogenic keratocyst : a preliminary study", J Oral Maxillofac Surg, 64, pp.379~383 (2006)[DOI]
- Myoung H, "Odontogenic keratocyst : review of 256 cases for recurrence and clinicopathologic parameters", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 91, pp.328~333 (2001)[DOI]
- Chirapathomsakul D, "A review of odontogenic keratocysts and the behavior of recurrences", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 101, pp.5~9 (2006)[DOI]
- Khan AA, "Management of an extensive odontogenic keratocyst : a rare case report with 10-year follow-up", Medicine(Baltimore), 98, pp.e17987~ (2019)[DOI]
- Kaczmarzyk T, "A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities", Int J Oral Maxillofac Surg, 41, pp.756~767 (2012)[DOI]
- Blanas N, "Systematic review of the treatment and prognosis of the odontogenic keratocyst", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 90, pp.553~558 (2000)[DOI]
- Jo Hyun-Jun, "A clinical study of inferior alveolar nerve damage caused by Carnoy’s solution used as a complementary therapeutic agent in a cystic lesion", Maxillofacial Plastic Reconstructive Surgery, 42(5), pp.1~8 (2020), 대한악안면성형재건외과학회[DOI]
- Donnelly LA, "Modified Carnoy's compared to Carnoy's solution is equally effective in preventing recurrence of odontogenic keratocysts", J Oral Maxillofac Surg, 79, pp.1874~1881 (2021)[DOI]
- Alchalabi NJ, "Using Carnoy's solution in treatment of keratocystic odontogenic tumor", Ann Maxillofac Surg, 7, pp.51~56 (2017)[DOI]
- Lal B, "Role of Carnoy's solution as treatment adjunct in jaw lesions other than odontogenic keratocyst : a systematic review", Br J Oral Maxillofac Surg, 59, pp.729~741 (2021)[DOI]
- Altas E, "A case of a large dentigerous cyst containing a canine tooth in the maxillary antrum leading to epiphora", J Laryngol Otol, 111, pp.641~643 (1997)[DOI]
- Albright CR, "Large dentigerous cyst of the maxilla near the maxillary sinus : report of case", J Am Dent Assoc, 83, pp.1112~1115 (1971)[DOI]
- Ju-Yeon Cho, "Expansile dentigerous cyst invading the entire maxillary sinus: a case report", 대한구강악안면외과학회지, 38(4), pp.245~248 (2012), 대한구강악안면외과학회[DOI]