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Analyzing the Risk Factors of Mortality after Osteoporotic Hip Fractures Using the National Health Insurance Service Sample Cohort 2.0 Database

이진우|김두섭|Hoejeong Chung|Seok In Hong
대한고관절학회 (The Korean Hip Society)|2022.09|Hip and Pelvis|제34권 제3호|pp. 150-160|DOI https://doi.org/10.5371/hp.2022.34.3.150

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참고문헌

키워드

Big dataMortalityOsteoporotic fractureHip

초록

Purpose: The purpose of this study is to determine risk factors that affect mortality following osteoporotic hip fracture in patients 50 years or older using the National Health Insurance Service (NHIS) sample cohort 2.0 database. Materials and Methods: Data from 2,533 patients who satisfied the inclusion criteria for the NHIS sample cohort 2.0 database were used in this study. Data from patients who suffered osteoporotic hip fractures between 2002-2015 were used. An analysis of correlations between the incidence of osteoporotic hip fractures and various factors (sex, age, underlying diseases, etc.) was performed. Analysis of the associations between the mortality of osteoporotic hip fracture and the various factors with hazard ratio (HR) was performed using Cox regression models. Results: Patient observation continued for an average of 38.12±32.09 months. During the observation period, a higher incidence of hip fracture was observed in women; however, higher mortality following the fracture was observed in men (HR=0.728; 95% confidence interval [CI], 0.635-0.836). The incidence and mortality of fractures increased when there were increasing age, more than three underlying diseases (HR=1.945; 95% CI, 1.284-2.945), cerebrovascular diseases (HR=1.429; 95% CI, 1.232-1.657), and renal diseases (HR=1.248; 95% CI, 1.040-1.497). Also, higher mortality was observed in patients who were underweight (HR=1.342; 95% CI, 1.079-1.669), current smokers (HR=1.338; 95% CI, 1.104-1.621), and inactivity (HR=1.379; 95% CI, 1.189-1.601). Conclusion: Male gender, the presence of cerebrovascular or kidney disease, a more than three underlying diseases, underweight, a current smoker, and inactivity were risk factors that increased mortality.

Abstract

Purpose: The purpose of this study is to determine risk factors that affect mortality following osteoporotic hip fracture in patients 50 years or older using the National Health Insurance Service (NHIS) sample cohort 2.0 database. Materials and Methods: Data from 2,533 patients who satisfied the inclusion criteria for the NHIS sample cohort 2.0 database were used in this study. Data from patients who suffered osteoporotic hip fractures between 2002-2015 were used. An analysis of correlations between the incidence of osteoporotic hip fractures and various factors (sex, age, underlying diseases, etc.) was performed. Analysis of the associations between the mortality of osteoporotic hip fracture and the various factors with hazard ratio (HR) was performed using Cox regression models. Results: Patient observation continued for an average of 38.12±32.09 months. During the observation period, a higher incidence of hip fracture was observed in women; however, higher mortality following the fracture was observed in men (HR=0.728; 95% confidence interval [CI], 0.635-0.836). The incidence and mortality of fractures increased when there were increasing age, more than three underlying diseases (HR=1.945; 95% CI, 1.284-2.945), cerebrovascular diseases (HR=1.429; 95% CI, 1.232-1.657), and renal diseases (HR=1.248; 95% CI, 1.040-1.497). Also, higher mortality was observed in patients who were underweight (HR=1.342; 95% CI, 1.079-1.669), current smokers (HR=1.338; 95% CI, 1.104-1.621), and inactivity (HR=1.379; 95% CI, 1.189-1.601). Conclusion: Male gender, the presence of cerebrovascular or kidney disease, a more than three underlying diseases, underweight, a current smoker, and inactivity were risk factors that increased mortality.

참고문헌 (37)

  1. Lim S, "Incidence of hip fractures in Korea", J Bone Miner Metab, 26, pp.400~405 (2008)[DOI]
  2. Choi HJ, "Burden of osteoporosis in adults in Korea : a national health insurance database study", J Bone Miner Metab, 30, pp.54~58 (2012)[DOI]
  3. Gong HS, "Patients with wrist fractures are less likely to be evaluated and managed for osteoporosis", J Bone Joint Surg Am, 91, pp.2376~2380 (2009)[DOI]
  4. 최의성, "한국에서의 고관절 골절 빈도는 여전히 증가 추세인가?: 건강보험 데이터베이스를 이용한 역학연구", 대한정형외과학회지, 51(6), pp.447~454 (2016), 대한정형외과학회
  5. Ray NF, "Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995 : report from the National Osteoporosis Foundation", J Bone Miner Res, 12, pp.24~35 (1997)[DOI]
  6. Melton LJ 3rd, "Adverse outcomes of osteoporotic fractures in the general population", J Bone Miner Res, 18, pp.1139~1141 (2003)[DOI]
  7. Schnell S, "The 1-year mortality of patients treated in a hip fracture program for elders", Geriatr Orthop Surg Rehabil, 1, pp.6~14 (2010)[DOI]
  8. Panula J, "Mortality and cause of death in hip fracture patients aged 65 or older : a population-based study", BMC Musculoskelet Disord, 12, pp.105~ (2011)[DOI]
  9. 김상림, "Incidence of Hip Fractures in Jeju Island, South Korea: A Prospective Study (2002-2006)", Clinics in Orthopedic Surgery, 2(2), pp.64~68 (2010), 대한정형외과학회
  10. "Population projection (2017-2067)" (2019)[URL]
  11. 박찬미, "건강보험데이타베이스를 이용한 골다공증성 고관절 골절 식별 및 타당도", Hip and Pelvis, 22(4), pp.305~311 (2010), 대한고관절학회
  12. White BL, "Rate of mortality for elderly patients after fracture of the hip in the 1980’s", J Bone Joint Surg Am, 69, pp.1335~1340 (1987)
  13. Keene GS, "Mortality and morbidity after hip fractures", BMJ, 307, pp.1248~1250 (1993)[DOI]
  14. AharonoffGB, "Hip fractures in the elderly : predictors of one year mortality", J Orthop Trauma, 11, pp.162~165 (1997)[DOI]
  15. Elliott J, "Predicting survival after treatment for fracture of the proximal femur and the effect of delays to surgery", J Clin Epidemiol, 56, pp.788~795 (2003)[DOI]
  16. Roche JJ, "Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people : prospective observational cohort study", BMJ, 331, pp.1374~ (2005)[DOI]
  17. von FriesendorffM, "Long-term survival and fracture risk after hip fracture : a 22-year follow-up in women", J Bone Miner Res, 23, pp.1832~1841 (2008)[DOI]
  18. 최준철, "80세 이상의 고관절주위 골절의 치료 후 사망률", Hip and Pelvis, 18(3), pp.116~120 (2006), 대한고관절학회
  19. 김동수, "노령의 고관절 골절 환자의 술 후 사망률 및 관련 인자", 대한정형외과학회지, 43(4), pp.488~494 (2008), 대한정형외과학회
  20. 장준동, "90세 이상 고령의 고관절부 골절 환자에서 시행한 양극성 반치환술 - 사망률에 영향을 준 요인들 -", Hip and Pelvis, 22(4), pp.283~290 (2010), 대한고관절학회
  21. https :, , doi, 10. 5371, pp.jkhs. 2010. 22. 4. 28321. Sullivan KJ, Husak LE, Altebarmakian M, Brox WT. Demographic factors in hip fracture incidence and mortality rates in California, 2000-2011, J Orthop Surg Res[DOI]
  22. 하용찬, "Trend in Hip Fracture Incidence and Mortality in Korea: A Prospective Cohort Study from 2002 to 2011", Journal of Korean Medical Science, 30(4), pp.483~488 (2015), 대한의학회
  23. Lee SA, "The effect of socioeconomic factors on health screening on Korea : the 2001 Korean National Examination Health and Nutrition Surveys(KNEHANS)", J Korean Assoc Cancer Prev, 9, pp.188~198 (2004)[DOI]
  24. Hoebel J, "Determinants of health check attendance in adults : findings from the cross-sectional German Health Update(GEDA)study", BMC Public Health, 14, pp.913~ (2014)[DOI]
  25. Meyer HE, "Body height, body mass index, and fatal hip fractures : 16 years’ follow-up of 674, 000Norwegian women and men", Epidemiology, 6, pp.299~305 (1995)[DOI]
  26. Akinleye SD, "The role of BMI in hip fracture surgery", Geriatr Orthop Surg Rehabil, 9, pp.2151458517747414~ (2018)[DOI]
  27. Prieto-Alhambra D, "Relationship between mortality and BMI after fracture : a population-based study of men and women aged ≥40 years", J Bone Miner Res, 29, pp.1737~1744 (2014)[DOI]
  28. 김유근, "Effect of Sarcopenia on Postoperative Mortality in Osteoporotic Hip Fracture Patients", 대한골대사학회지, 25(4), pp.227~233 (2018), 대한골대사학회
  29. 유준일, "Osteosarcopenia in Patients with Hip Fracture Is Related with High Mortality", Journal of Korean Medical Science, 33(4), pp.37~45 (2018), 대한의학회
  30. Peterson MG, "Fiveyear survival in a cohort of hip fracture patients : the predictive role of pre-fracture health status", HSS J, 4, pp.43~47 (2008)[DOI]
  31. Seitz DP, "Effects of impairment in activities of daily living on predicting mortality following hip fracture surgery in studies using administrative healthcare databases", BMC Geriatr, 14, pp.9~ (2014)[DOI]
  32. Forni C, "Predictive factors for thirty day mortality in geriatric patients with hip fractures : a prospective study", Int Orthop, 43, pp.275~281 (2019)[DOI]
  33. Solbakken SM, "Excess mortality following hip fracture : impact of self-perceived health, smoking, and body mass index. A NOREPOS study", Osteoporos Int, 28, pp.881~887 (2017)[DOI]
  34. Vosoughi AR, "Factors increasing mortality of the elderly following hip fracture surgery : role of body mass index, age, and smoking", Musculoskelet Surg, 101, pp.25~29 (2017)[DOI]
  35. A study on the operational definition of disease based on national health insurance claim, "Kim DW", NHIS Ilsan Hospital Institute Health Insurance & Clinical Research, ~, pp.2017-20-029 (2017)
  36. Tolppanen AM, "Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer’s disease-exposure-matched cohort study", BMC Geriatr, 16, pp.204~ (2016)[DOI]
  37. 안승희, "Osteoporosis and Osteoporotic Fracture Fact Sheet in Korea", 대한골대사학회지, 27(4), pp.281~290 (2020), 대한골대사학회

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