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Efficacy of Pericapsular Nerve Group Block for Pain Reduction and Opioid Consumption after Total Hip Arthroplasty: A Meta-Analysis of Randomized Controlled Trials

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초록

The aim of this study was to conduct a meta-analysis of randomized controlled trials (RCTs) for comparison of the effectiveness of pericapsular nerve group (PENG) block with that of other analgesic techniques for reduction of postoperative pain and consumption of opioids after total hip arthroplasty (THA). A search of records in the PubMed, Embase, and Cochrane Library, and ClinicalTrials.gov databases was conducted in order to identify studies comparing the effect of the PENG block with that of other analgesics on reduction of postoperative pain and consumption of opioids after THA. Determination of eligibility was based on the PICOS (participants, intervention, comparator, outcomes, and study design) criteria as follows: (1) Participants: patients who underwent THA. (2) Intervention: patients who received a PENG block for management of postoperative pain. (3) Comparator: patients who received other analgesics. (4) Outcomes: numerical rating scale (NRS) score and opioid consumption during different periods. (5) Study design: clinical RCTs. Five RCTs were finally included in the current meta-analysis. Significantly lower postoperative opioid consumption at 24 hours after THA was observed in the group of patients who received the PENG block compared with the control group (standard mean difference=–0.36, 95% confidence interval –0.64 to –0.08). However, no significant reduction in NRS score at 12, 24, and 48 hours after surgery and opioid consumption at 48 hours after THA was observed. The PENG block showed better results for opioid consumption at 24 hours after THA compared with other analgesics.

Abstract

The aim of this study was to conduct a meta-analysis of randomized controlled trials (RCTs) for comparison of the effectiveness of pericapsular nerve group (PENG) block with that of other analgesic techniques for reduction of postoperative pain and consumption of opioids after total hip arthroplasty (THA). A search of records in the PubMed, Embase, and Cochrane Library, and ClinicalTrials.gov databases was conducted in order to identify studies comparing the effect of the PENG block with that of other analgesics on reduction of postoperative pain and consumption of opioids after THA. Determination of eligibility was based on the PICOS (participants, intervention, comparator, outcomes, and study design) criteria as follows: (1) Participants: patients who underwent THA. (2) Intervention: patients who received a PENG block for management of postoperative pain. (3) Comparator: patients who received other analgesics. (4) Outcomes: numerical rating scale (NRS) score and opioid consumption during different periods. (5) Study design: clinical RCTs. Five RCTs were finally included in the current meta-analysis. Significantly lower postoperative opioid consumption at 24 hours after THA was observed in the group of patients who received the PENG block compared with the control group (standard mean difference=–0.36, 95% confidence interval –0.64 to –0.08). However, no significant reduction in NRS score at 12, 24, and 48 hours after surgery and opioid consumption at 48 hours after THA was observed. The PENG block showed better results for opioid consumption at 24 hours after THA compared with other analgesics.

참고문헌 (27)

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관련 논문AI추천

Pericapsular Nerve Group Block with Periarticular Injection for Pain Management after Total Hip Arthroplasty: A Randomized Controlled Trial권혁민, 박관규, 박준영, 이보라, 이우석, 이태성, 조훈식, 최용선, 함형원연세대학교의과대학 · Yonsei Medical Journal2025 · 제66권 제4호Comparison of Analgesic Efficacy between Ultrasound-guided Supra-inguinal Fascia Iliaca Block and Pericapsular Nerve Group Block following Total Hip Arthroplasty: A Randomized Controlled TrialAree Tanavalee, Chotetawan Tanavalee, Chutikant Vichainarong, Pongkwan Jinaworn, Srihatach Ngarmukos, Wirinaree Kampitak대한고관절학회 · Hip and Pelvis2024 · 제36권 제4호A meta-analysis on advantages of peripheral nerve block post-total knee arthroplastyDi Li, Di You, Guoqing Zhao, Kai Li, Longyun Li, Lu Qin대한통증학회 · The Korean Journal of Pain2021 · 제34권 제3호Pain Control after Total Hip Replacement Arthroplasty Using Periarticular Multimodal Drug Injection곽희철, 김정원, 김정한, 민영경, 최장석대한고관절학회 · Hip and Pelvis2010 · 제22권 제4호Ultrasound-guided PENG block versus intraarticular corticosteroid injection in hip osteoarthritis: a randomised controlled studyFeyza Celikel, Halil Cihan Kose, Omer Taylan Akkaya, Selin Guven Kose, Serkan Tulgar대한통증학회 · The Korean Journal of Pain2023 · 제36권 제2호The effects of continuous catheter adductor canal block for pain management in knee replacement therapy: a meta-analysisAiden Jabur, Asher Dixon, Hayden Randall, Hyun Jae Nam, Jing Sun, Tynan Cox대한슬관절학회 · Knee Surgery and Related Research2023 · 제35권

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