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일개대학병원에서 수막알균 백신 사용의 경험

A Case Study of Meningococcal Vaccination At a University Hospital

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참고문헌

주제분류내과학

초록

Abstract

Meningococcal infection is a life threatening disease that leaves serious sequelae in spite of appropriate treatment, thus vaccination for high risk groups are important for the prevention of meningococcal diseases. However, the vaccine for Neisseria meningitidis has not been available in Korea until we introduced bivalent (serogroup A and C) polysaccharide vaccine for the first time for relief works in our university hospital. The vaccine was administered from January 2005 to March 2007 to 317 persons. Of the groups administered, the largest group among them were 133 (133/317, 42%) students who planned to study abroad and needed the vaccination for secure entrance to school dormitories. This group was followed by health care workers, travellers to the regions of the world with high risks of meningococcal diseases, and splenectomised patients. To rationalize the domestic use of meningococcal vaccine, the availability of vaccines first needs to be simplified by introducing them to the domestic market; for this to be possible, the approval system for vaccines should be reformed and epidemiogical studies need to be carried out.

참고문헌 (7)

  1. Mandell GL, "Principles and Practice of Infectious Diseases", pp.2498~2513 (2005), Churchill Livingstone
  2. Orenstein WA, "Vaccines", pp.959~ (2004), Saunders
  3. Centers for Disease Control and Prevention, "Prevention and Control of Meningococcal Disease Recommendations of the Advisory Committee on Immunization Practices (ACIP)", 54, pp.1~21 (2005)
  4. KimYS, "Meningococcal disease in the Republic of Korea Army incidence and serogroups determined by PCR", 18, pp.163~166 (2003)
  5. Choi S, "Clinical and Epidemiologic Features of Meningococcal Infections in Incheon", 37, pp.119~126 (2005)
  6. "The Ministry of National Defense, The Republic of Korea: Defense White Paper 2006 Availble from" (2007)
  7. Park HS, "Vaccination effect on pharyngeal carrier rate of Neisseria meningitidis and its serogroups in Korean Army recruits", pp.105~15 (1992)

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