본문 바로가기
KERD
논문KCI 등재

경막 내 colistimethate 투여로 치료한 다제 내성 Acinetobacter baumannii 뇌실염

A Case of Multidrug-resistant Acinetobacter baumannii Ventriculitis Successfully Treated with Intrathecal Colistimethate

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류내과학

초록

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

Abstract

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

참고문헌 (17)

  1. Bergogne-Brzin E, "Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features", Clin Microbiol Rev, 9, pp.148~165 (1996)
  2. Blot S, "Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study", Intensive Care Med, 29, pp.471~475 (2003)
  3. Jawad A, "Influence of relative humidity and suspending menstrua on survival of Acinetobacter spp. on dry surfaces", J Clin Microbiol, 34, pp.2881~2887 (1996)
  4. Fournier PE, "The epidemiology and control of Acinetobacter baumannii in health care facilities", Clin Infect Dis, 42, pp.692~699 (2006)
  5. Fernandez-Viladrich P, "Successful treatment of ventriculitis due to carbapenem-resistant Acinetobacter baumannii with intraventricular colistin sulfomethate sodi", Clin Infect Dis, 28, pp.916~917 (1999)
  6. Vasen W, "Ilutovich S, Di Martino A. Intrathecal use of colistin", J Clin Microbiol, 38, pp.3523~ (2000)
  7. Ho YH, "Successful treatment of meningitis caused by multidrug-resistant Acinetobacter baumannii with intravenous and intrathecal colistin", J Micobiol Immunol Infect, 40, pp.537~540 (2007)
  8. Katragkou A, "Successful treatment of multidrug resistant Acinetobacter baumannii central nervous system infections with colistin", J Clin Microbiol, 43, pp.4916~4917 (2005)
  9. Ng J, "Cure of multiresistant Acinetobacter baumannii central nervous system infections with intraventricular or intrathecal colistin: case series and literature review", J Antimicrob Chemother, 58, pp.1078~1081
  10. Seifert H, "Clinical and bacteriological features of relapsing shunt-associated meningitis due to Acinetobacter baumannii", Eur J Clin Microbiol Infect Dis, 14, pp.130~134 (1995)
  11. Bonomo RA, "Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa", Clin Infect Dis 43(Suppl 2), pp.49~56 (2006)
  12. Falagas ME, "Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections", Clin Infect Dis, 40, pp.1333~1341 (2005)
  13. Benedict RG, "Antibiotic activity of Bacillus polymyxa", J Bacteriol, 54, pp.24~25 (1947)
  14. Wang KW, "Post- neurosurgical nosocomial bacterial meningitis in adults: microbiology, clinical features, and outcomes", J Clin Neurosci, 12, pp.647~650 (2005)
  15. Kunin CM, "Binding of polymyxin antibiotics to tissues: the major determinant of distribution and persistence in the body", J Infect Dis, 124, pp.394~400 (1971)
  16. Craig WA, "Significance of serum protein and tissue binding of antimicrobial agents", Ann Rev Med, 27, pp.287~300 (1976)
  17. Jimnez-Mejas ME, "Cerebrospinal fluid penetration and pharmacokinetic", pharmacodynamic parameters of intravenously administered colistin in a case of multidrug-resistant Acinetobacter baumannii meningitis, 2002, pp.21, 212~214

관련 논문AI추천

이 간행물의 다른 논문 (9건)