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Staphylococcus epidermidis에 의한 자연판막 심내막염 1례

A Case of Native Valve Endocarditis due to Staphylococcus epidermidis

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초록

Although Staphylococcus epidermidis is a frequent cause of prosthetic valve endocarditis (PVE), it is regarded as a rare pathogen of native valve endocarditis (NVE). We report a case of NVE caused by methicillin-resistant S. epidermidis in a 62-year-old man. The bacterium was isolated from blood and tissue culture. The patient underwent valve replacement due to heart failure and was successfully treated by surgery and vancomycin administration for 7 weeks.

Abstract

Although Staphylococcus epidermidis is a frequent cause of prosthetic valve endocarditis (PVE), it is regarded as a rare pathogen of native valve endocarditis (NVE). We report a case of NVE caused by methicillin-resistant S. epidermidis in a 62-year-old man. The bacterium was isolated from blood and tissue culture. The patient underwent valve replacement due to heart failure and was successfully treated by surgery and vancomycin administration for 7 weeks.

참고문헌 (12)

  1. Chu VH, "International Collaboration on Endocarditis-Prospective Cohort Study Group. Emergence of coagulase-negative staphylococci as a cause of native valve endocarditis", Clin Infect Dis, 46, pp.232~242 (2008)
  2. Rogers KL, "Coagulase-negative staphylococcal infections", Infect Dis Clin N Am, 23, pp.73~98 (2009)
  3. Abelsi I, "Native valve infective endocarditis in a tertiary care center in a developing country (Tunisia)", Am J Cardiol, 102, pp.1247~1251 (2008)
  4. Lee CH, "Epidemiologic features of infective endocarditis in Taiwanese adults involving native valves", Am J Cardiol, 100, pp.1282~1285 (2007)
  5. 손준성, "감염성 심내막염의 임상양상 관찰", Infection and Chemotherapy, 37(3), pp.152~160 (2005), 대한감염학회
  6. Chu VH, "International Collaboration on Endocarditis Merged Database Study Group. Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the international collaboration on endocarditis merged database", Clin Infect Dis, 39, pp.1527~1530 (2004)
  7. Vuong C, "Staphylococcus epidermidis infections", Microbes Infect, 4, pp.481~491 (2002)
  8. Ziebuhr W, "Nosocomial infections by Staphylococcus epidermidis: how a commensal bacterium turns into a pathogen", Int J Antimicrob Agents 28 Suppl, 1, pp.S14~20 (2006)
  9. Beekmann SE, "Determining the clinical significance of coagulase-negative staphylococci isolated from blood cultures", Infect Control Hosp Epidemiol, 26, pp.559~566 (2005)
  10. Tokars JI,
  11. Raad I, "Staphylococcus epidermidis: emerging resistance and need for alternative agents", Clin Infect Dis, 26, pp.1182~1187 (1998)
  12. Tomasz A, "Stable classes of phenotypic expression in methicillin-resistant clinical isolates of staphylococci", Antimicrob Agents Chemother, 35, pp.124~129 (1991)

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