본문 바로가기
KERD
논문KCI 등재

대유행 인플루엔자(H1N1 2009) 감염과 연관된 폐쇄 세기관지 기질화 폐렴 1예

A Case of Bronchiolitis Obliterans Organizing Pneumonia Associated with Pandemic Influenza (H1N1 2009)

0

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류내과학

초록

Several types of influenza-related pneumonia have been reported. Bronchiolitis obliterans organizing pneumonia (BOOP) is a nonspecific lung injury. A 64-yearold man sought care to an emergency room due to breathing difficulties. He was diagnosed with pandemic influenza (H1N1 2009) by the real-time polymerase chain reaction (PCR) and was suspected of concomitant bacterial pneumonia. Therefore he was treated with oseltamivir and broad spectrum antibiotics. The disease progressed rapidly despite treatment, so a corticosteroid was added. The trans-bronchial lung biopsy was consistent with BOOP. Here,we investigated BOOP associated with the pandemic influenza (H1N1 2009)virus that was successfully treated with a combination of antiviral, antibacterial and corticosteroid drugs. Although BOOP associated with influenza is rare,combined disease should be suspected especially when the pneumonia does not response to antiviral agents and antibiotics.

Abstract

Several types of influenza-related pneumonia have been reported. Bronchiolitis obliterans organizing pneumonia (BOOP) is a nonspecific lung injury. A 64-yearold man sought care to an emergency room due to breathing difficulties. He was diagnosed with pandemic influenza (H1N1 2009) by the real-time polymerase chain reaction (PCR) and was suspected of concomitant bacterial pneumonia. Therefore he was treated with oseltamivir and broad spectrum antibiotics. The disease progressed rapidly despite treatment, so a corticosteroid was added. The trans-bronchial lung biopsy was consistent with BOOP. Here,we investigated BOOP associated with the pandemic influenza (H1N1 2009)virus that was successfully treated with a combination of antiviral, antibacterial and corticosteroid drugs. Although BOOP associated with influenza is rare,combined disease should be suspected especially when the pneumonia does not response to antiviral agents and antibiotics.

참고문헌 (19)

  1. Hui DS, "Clinical management of pandemic 2009 influenza A(H1N1) infection", Chest, 137, pp.916~925 (2010)
  2. 김우주, "신종인플루엔자 A", H1N1 대유행: 현황과 전망, 2009, pp.52(8), 787~794[DOI]
  3. Epler GR, "Bronchiolitis obliterans organizing pneumonia", N Engl J Med, 312, pp.152~158 (1985)
  4. Cordier JF, "Cryptogenic organising pneumonia", Eur Respir J, 28, pp.422~446 (2006)
  5. Gill JR, "Pulmonary pathologic findings of fatal 2009 pandemic influenza A", H1N1 viral infections, 2010, pp.134, 235~243
  6. Centers for Disease Control and Prevention (CDC), "Surveillance for pediatric deaths associated with 2009 pandemic influenza A (H1N1) virus infection - United States, April- August 2009", MMWR Morb Mortal Wkly Rep, 58, pp.941~947 (2009)
  7. Barlow GD, "Swine flu and antibiotics", J Antimicrob Chemother, 64, pp.889~894 (2009)
  8. Stockman LJ, "SARS: systematic review of treatment effects", PLoS Med, 3, pp.e343~ (2006)
  9. Lai ST, "Treatment of severe acute respiratory syndrome", Eur J Clin Microbiol Infect Dis, 24, pp.583~591 (2005)
  10. Luke TC, "Metaanalysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?", Ann Intern Med, 145, pp.599~609 (2006)
  11. Costabel U, "BOOP in Europe", Chest, 102(1), pp.S14~S20 (1992)
  12. Purcell IF, "Cyclophosphamide in severe steroid-resistant bronchiolitis obliterans organizing pneumonia", Respir Med, 91, pp.175~177 (1997)
  13. Kobayashi I, "Interstitial lung disease associated with juvenile dermatomyositis: clinical features and efficacy of cyclosporin A", Rheumatology (Oxford), 42, pp.371~374 (2003)
  14. Kim EA, "Viral pneumonias in adults: radiologic and pathologic findings", Radiographics, 22(Spec), pp.S137~S149 (2002)
  15. Agarwal PP, "Chest radiographic and CT findings in novel swine-origin influenza A (H1N1) virus (S-OIV) infection", AJR Am J Roentgenol, 193, pp.1488~1493 (2009)
  16. Ajlan AM, "Swine-origin inf luenza A (H1N1) viral infection: radiographic and CT findings", AJR Am J Roentgenol, 193, pp.1494~1499 (2009)
  17. Aviram G, "H1N1 influenza: initial chest radiographic findings in helping predict patient outcome", Radiology, 255, pp.252~259 (2010)
  18. JoonChang, "Bronchiolitis Obliterans Organizing Pneumonia: Clinicopathologic Review of a Series of 45 Korean Patients Including Rapidly Progressive form", Journal of Korean Medical Science, 17(2), pp.179~186 (2002), 대한의학회
  19. 나형중, "BOOP 형태로 발현된 Epstein-Barr Virus 폐렴 1예", Tuberculosis and Respiratory Diseases, 62(1), pp.51~55 (2007), 대한결핵및호흡기학회

관련 논문AI추천

이 간행물의 다른 논문 (15건)