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Propofol 투여 후 발생한 Escherichia coli 패혈성 쇼크 1예

A Case of Septic Shock Caused by Escherichia coli after Intravenous Injection of Contaminated Propofol

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초록

Propofol (2,6-diisopropylphenol) is a rapid and short-acting anesthetic agent that is used for general anesthesia and endoscopic sedation. It is available as an aqueous lipid emulsion and this preparation could serve as a bacterial culture medium. We report a case of a 46-year-old female who developed septic shock caused by Escherichia coli after being sedated by propofol to undergo gastrointestinal endoscopy. The contaminated propofol was identified as the cause of septic shock by pulsed-gel electrophoresis.

Abstract

Propofol (2,6-diisopropylphenol) is a rapid and short-acting anesthetic agent that is used for general anesthesia and endoscopic sedation. It is available as an aqueous lipid emulsion and this preparation could serve as a bacterial culture medium. We report a case of a 46-year-old female who developed septic shock caused by Escherichia coli after being sedated by propofol to undergo gastrointestinal endoscopy. The contaminated propofol was identified as the cause of septic shock by pulsed-gel electrophoresis.

참고문헌 (11)

  1. Heuss LT, "The dawning of a new sedative: propofol in gastrointestinal endoscopy", Digestion, 69, pp.20~26 (2004)
  2. Crowther J, "Growth of microorganisms in propofol, thiopental, and a 1:1 mixture of propofol and thiopental", Anesth Analg, 82, pp.475~478 (1996)
  3. Bennett SN, "Postoperative infections traced to contamination of an intravenous anesthetic, propofol", N Engl J Med, 333, pp.147~154 (1995)
  4. Crocker KS, "Microbial growth comparisons of five commercial parenteral lipid emulsions", J Parenter Enteral Nutr, 8, pp.391~395 (1984)
  5. Jarvis WR, "Bacterial growth and endotoxin production in lipid emulsion", J Clin Microbiol, 19, pp.17~20 (1984)
  6. Tessler M, "Growth curves of Staphylococcus aureus, Candida albicans, and Moraxella osloensis in propofol and other media", Can J Anaesth, 39, pp.509~511 (1992)
  7. Veber B, "Severe sepsis after intravenous injection of contaminated propofol", Anesthesiology, 80, pp.712~713 (1994)
  8. McHugh GJ, "Propofol emulsion and bacterial contamination", Can J Anaesth, 42, pp.801~804 (1995)
  9. Muscarella LF, "Infection control and its application to the administration of intravenous medications during gastrointestinal endoscopy", Am J Infect Control, 32, pp.282~286 (2004)
  10. Henry B, "An outbreak of Serratia marcescens associated with the anesthetic agent propofol", Am J Infect Control, 29, pp.312~315 (2001)
  11. Nichols RL, "Bacterial contamination of an anesthetic agent", N Engl J Med, 333, pp.184~185 (1995)

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