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우리나라 암 환자에서의 대유행 인플루엔자 A/H1N1 2009 감염의 특성

Clinical and Laboratory Characteristics of Pandemic Influenza A/H1N1 2009 Infection among Patients with Malignancy in Korea

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초록

Background: Patients with malignancy are considered to be at high risk of severe pandemic influenza A/H1N1 2009. This study was conducted to identify the severity of pandemic influenza A/H1N1 2009 among patients with malignancy. Materials and Methods: Between August 2009 and December 2009, we reviewed clinical data and medical records of 31 patients with malignancy and 63hospitalized patients without malignancy. Results: Eighty-three patients with laboratory-confirmed pandemic influenza A/H1N1 2009 were admitted. The rate of ICU admission was higher among patients with malignancy (without malignancy 13% vs with malignancy 35%, P=0.024). The mortality rate was higher among patients with malignancy (without malignancy 6%vs with malignancy 25%, P=0.033). Patients using immunosuppressants showed a higher rate of lower respiratory tract infection (83% vs 24%, P=0.013). Conclusions: Pandemic influenza A/H1N1 2009 in patients with malignancy was more severe than in patients without malignancy.

Abstract

Background: Patients with malignancy are considered to be at high risk of severe pandemic influenza A/H1N1 2009. This study was conducted to identify the severity of pandemic influenza A/H1N1 2009 among patients with malignancy. Materials and Methods: Between August 2009 and December 2009, we reviewed clinical data and medical records of 31 patients with malignancy and 63hospitalized patients without malignancy. Results: Eighty-three patients with laboratory-confirmed pandemic influenza A/H1N1 2009 were admitted. The rate of ICU admission was higher among patients with malignancy (without malignancy 13% vs with malignancy 35%, P=0.024). The mortality rate was higher among patients with malignancy (without malignancy 6%vs with malignancy 25%, P=0.033). Patients using immunosuppressants showed a higher rate of lower respiratory tract infection (83% vs 24%, P=0.013). Conclusions: Pandemic influenza A/H1N1 2009 in patients with malignancy was more severe than in patients without malignancy.

참고문헌 (14)

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