단독과 연조직염의 임상적 특성과 원인균에 관한 연구
Clinical Characteristics and Organisms Causing Erysipelas and Cellulitis
1
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Background: Although erysipelas and cellulitis are common soft tissue infectious diseases, there have been a few studies which investigate clinical characteristics and causative organisms in Korea. Materials and Methods: We retrospectively reviewed the medical records of patients who had been diagnosed with erysipelas or cellulitis from ten general hospitals between January 2009 and February 2011. Results: During the study period, a total of 144 patients with erysipelas and 735 with cellulitis were recruited. The mean age of erysipelas patients was 53.6 years, and that of cellulitis patients was 47.5 years. Diabetes mellitus was the most common underlying disease in both groups. The most common site of erysipelas was the face (80.6%) and that of cellulitis was the lower extremity (64.9%). Culture studies have been done in 31.9% (46/144) of patients with erysipelas, and 41.1% (302/735)with cellulites. Causative organisms were identified in 3 patients (2.1%) with erysipelas and 57 (7.8%) with cellulitis. Streptococcus pyogenes was isolated from two patients with erysipelas, and group G streptococcus from one. Staphylococcus aureus (44.0%) was the most common isolate in patients with cellulitis, followed by streptococci (27.1%), Enteobateriaceae (11.9%), and Vibrio species (6.8%). Firstgeneration cephalosporin was the most commonly used antimicrobial agent in both groups. Conclusions: β -hemolytic streptococcus and S. aureus were the most common causative organisms of patients with erysipelas and cellulitis.
Abstract
Background: Although erysipelas and cellulitis are common soft tissue infectious diseases, there have been a few studies which investigate clinical characteristics and causative organisms in Korea. Materials and Methods: We retrospectively reviewed the medical records of patients who had been diagnosed with erysipelas or cellulitis from ten general hospitals between January 2009 and February 2011. Results: During the study period, a total of 144 patients with erysipelas and 735 with cellulitis were recruited. The mean age of erysipelas patients was 53.6 years, and that of cellulitis patients was 47.5 years. Diabetes mellitus was the most common underlying disease in both groups. The most common site of erysipelas was the face (80.6%) and that of cellulitis was the lower extremity (64.9%). Culture studies have been done in 31.9% (46/144) of patients with erysipelas, and 41.1% (302/735)with cellulites. Causative organisms were identified in 3 patients (2.1%) with erysipelas and 57 (7.8%) with cellulitis. Streptococcus pyogenes was isolated from two patients with erysipelas, and group G streptococcus from one. Staphylococcus aureus (44.0%) was the most common isolate in patients with cellulitis, followed by streptococci (27.1%), Enteobateriaceae (11.9%), and Vibrio species (6.8%). Firstgeneration cephalosporin was the most commonly used antimicrobial agent in both groups. Conclusions: β -hemolytic streptococcus and S. aureus were the most common causative organisms of patients with erysipelas and cellulitis.
참고문헌 (21)
- Swartz MN., "Clinical practice. Cellulitis", N Engl J Med, 350, pp.904~912 (2004)
- Morris AD., "Cellulitis and erysipelas", Clin Evid (Online) , pii,1708, ~ (2008)
- Pasternack MS., "Cellulitis, necrotizing fascitis, and subcutaneous tissue infections, In Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed", pp.1289~1312 (2009), Saunders Elsevier
- Baddour LM., "Recurrent cellulitis after saphenous venectomy for coronary bypass surgery", Ann Intern Med, 97, pp.493~496 (1982)
- Dankert J., "Recurrent acute leg cellulitis after hysterectomy with pelvic lymphadenectomy", Br J Obstet Gynaecol, 94, pp.788~790 (1987)
- Simon MS., "Cellulitis after axillary lymph node dissection for carcinoma of the breast", Am J Med, 93, pp.543~548 (1992)
- Dupuy A., "Risk factors for erysipelas of the leg(cellulitis) : case-control study", BMJ, 318, pp.1591~1594 (1999)
- Chartier C., "Erysipelas", Int J Dermatol, 29, pp.459~467 (1990)
- Chartier C., "Erysipelas : an update", Int J Dermatol, 35, pp.779~781 (1996)
- Stevens DL., "Practice guidelines for the diagnosis and management of skin and soft-tissue infections", Clin Infect Dis, 41, pp.1373~1406 (2005)
- Perl B., "Cost-effectiveness of blood cultures for adult patients with cellulitis", Clin Infect Dis, 29, pp.1483~1488 (1999)
- Woo PC., "Cellulitis complicating lymphoedema", Eur J Clin Microbiol Infect Dis, 19, pp.294~297 (2000)
- Hook EW 3rd., "Microbiologic evaluation of cutaneous cellulitis in adults", Arch Intern Med, 146, pp.295~297 (1986)
- Duvanel T., "Quantitative cultures of biopsy specimens from cutaneous cellulitis", Arch Intern Med, 149, pp.293~296 (1989)
- Kielhofner MA., "Influence of underlying disease process on the utility of cellulitis needle aspirates", Arch Intern Med, 148, pp.2451~2452 (1988)
- Sachs MK., "The optimum use of needle aspiration in the bacteriologic diagnosis of cellulitis in adults", Arch Intern Med, 150, pp.1907~1912 (1990)
- Bernard P., "Streptococcal cause of erysipelas and cellulitis in adults. A microbiologic study using a direct immunofluorescence technique", Arch Dermatol, 125, pp.779~782 (1989)
- 이재영, "연조직염 환자에서 피부 생검 조직 배양을 통한 원인균 검출률 향상에 관한 연구", 대한피부과학회지, 45(2), pp.134~139 (2007), 대한피부과학회
- Hahn SH., "Cellulitis in young adults", J Korean Orthop Assoc, 33, pp.614~619 (1998)
- Grayson ML., "Once-daily intravenous cefazolin plus oral probenecid is equivalent to once-daily intravenous ceftriaxone plus oral placebo for the treatment of moderateto-severe cellulitis in adults", Clin Infect Dis, 34, pp.1440~1448 (2002)
- Chan JC., "Ampicillin", sulbactam versus cefazolin or cefoxitin in the treatment of skin and skin-structure infections of bacterial etiology, 1995, pp.12, 139~146