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PET-CT에서 FDG 섭취증가를 보여 림프종으로 의심했던 복부 Kikuchi병 1예

A Case of Intra-Abdominal Kikuchi’s Disease with Increased FDG Uptake on PET-CT that Mimicked Intra- Abdominal Lymphoma

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키워드

주제분류내과학

초록

Kikuchi’s disease is a benign disease characterized mainly by fever and cervical lymphadenitis. We report a case of Kikuchi’s disease that manifested as intraabdominal lymphadenitis. A 39 year old woman presented with fever that had persisted for one week. Her history and physical examination were unremarkable. The laboratory findings revealed mild leukopenia and increased C-reactive protein. Abdominal CT revealed multiple lymph node enlargements in the mesenteric root and around the ileocecal valve. Positron emission tomography-computed tomography (PET-CT) revealed increased 18-fluoro-deoxyglucose(FDG) uptake in the lymph nodes observed by abdominal CT. A laparoscopic excisional biopsy of the lymph node was performed for a confirmatory diagnosis and the pathology findings were compatible with Kikuchi’s disease. Although intra-abdominal Kikuchi’s disease is a rare disease, it should be considered in a differential diagnosis of intraabdominal lymphadenopathy with increased FDG uptake on PET-CT

Abstract

Kikuchi’s disease is a benign disease characterized mainly by fever and cervical lymphadenitis. We report a case of Kikuchi’s disease that manifested as intraabdominal lymphadenitis. A 39 year old woman presented with fever that had persisted for one week. Her history and physical examination were unremarkable. The laboratory findings revealed mild leukopenia and increased C-reactive protein. Abdominal CT revealed multiple lymph node enlargements in the mesenteric root and around the ileocecal valve. Positron emission tomography-computed tomography (PET-CT) revealed increased 18-fluoro-deoxyglucose(FDG) uptake in the lymph nodes observed by abdominal CT. A laparoscopic excisional biopsy of the lymph node was performed for a confirmatory diagnosis and the pathology findings were compatible with Kikuchi’s disease. Although intra-abdominal Kikuchi’s disease is a rare disease, it should be considered in a differential diagnosis of intraabdominal lymphadenopathy with increased FDG uptake on PET-CT

참고문헌 (20)

  1. Kikuchi M., "Lymphadenitis showing focal reticulum cells hyperplasia with nuclear debris and phagocytosis : A clinicopathological study", Acta Hematol Jpn, 35, pp.379~380 (1972)
  2. Dorfman RF., "Kikuchi's histiocytic necrotizing lymphadenitis : an analysis of 108 cases with emphasis on differential diagnosis", Semin Diagn Pathol, 5, pp.329~345 (1988)
  3. Rudin C., "Mesenterial histiocytic necrotizing lymphadenitis. Case report", Helv Paediatr Acta, 42, pp.35~40 (1987)
  4. Yabe H., "Necrotizing lymphadenitis presenting as mesenteric lymphadenopathy", Rinsho Ketsueki, 40, pp.658~662 (1999)
  5. Kita Y., "A case of Kikuchi's disease with abdominal manifestations", Surgery, 122, pp.962~963 (1997)
  6. Rudniki C., "Kikuchi's necrotizing lymphadenitis : a cause of fever of unknown origin and splenomegaly", Acta Haematol, 79, pp.99~102 (1988)
  7. 윤영란, "급성 충수돌기염으로 오인된 장간막 림프절에 발생한 아급성 괴사성 림프절염 1례", Pediatric Gastroenterology, Hepatology & Nutrition, 6(1), pp.68~72 (2003), 대한소아소화기영양학회
  8. 오범진, "급성 충수돌기염으로 오인된 Kikuchi-Fujimoto 병 3례", 대한응급의학회지, 16(1), pp.194~199 (2005), 대한응급의학회
  9. Ito K., "Kikuchi disease : 18F-FDG positron emission tomography", computed tomography of lymph node uptake, 2010, pp.28, 15~19
  10. Tsujikawa T., "Kikuchi-Fujimoto disease : PET", CT assessment of a rare cause of cervical lymphadenopathy, 2011, pp.36, 661~664
  11. Turner RR., "Necrotizing lymphadenitis. A study of 30 cases", Am J Surg Pathol, 7, pp.115~123 (1983)
  12. Huh J., "A study of the viral etiology of histiocytic necrotizing lymphadenitis(Kikuchi-Fujimoto disease)", J Korean Med Sci, 13, pp.27~30 (1998)
  13. Ohshima K., "Perforin and Fas pathways of cytotoxic T-cells in histiocytic necrotizing lymphadenitis", Histopathology, 33, pp.471~478 (1998)
  14. Pileri SA., "Myeloperoxidase expression by histiocytes in Kikuchi's and Kikuchi-like lymphadenopathy", Am J Pathol, 159, pp.915~924 (2001)
  15. Famularo G., "Kikuchi Fujimoto lymphadenitis : case report and literature review", Am J Hematol, 74, pp.60~63 (2003)
  16. 한혜숙, "FDG PET-CT에서 악성림프종처럼 보이는 복부 기쿠치병", Nuclear Medicine and Molecular Imaging, 43(4), pp.363~365 (2009), 대한핵의학회
  17. Liao AC., "Cervical lymphadenopathy caused by Kikuchi disease : positron emission tomographic appearance", Clin Nucl Med, 28, pp.320~321 (2003)
  18. Kaicker S., "PET-CT scan in a patient with Kikuchi disease", Pediatr Radiol, 38, pp.596~597 (2008)
  19. Zhang MJ., "Lymph node uptake of 18F-fluorodeoxyglucose detected with positron emission tomography", computed tomography mimicking malignant lymphoma in a patient with Kikuchi disease, 2010, pp.10, 477~479
  20. 오주현, "Kikuchi disease mimicking malignant lymphoma on FDG PET", CT, 200709, pp.32(9), 711~712[DOI]

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