본문 바로가기
KERD
논문KCI 등재

Susceptibility of Glycopeptide-Resistant Enterococci to Linezolid, Quinupristin/dalfopristin, Tigecycline and Daptomycin in a Tertiary Greek Hospital

2

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류내과학

초록

We investigated the antibiotic susceptibility of glycopeptide-resistant enterococci (GRE). Seventy consecutive GRE were tested. Sixty-two isolates were identified as Enterococcus faecium (88.6%), and 8 (11.4%) as Enterococcus faecalis. All strains weresusceptible to linezolid and daptomycin, while 17.1% (12/70) and 11.4% (8/70) were resistant to quinupristin/dalfopristin (QD)and tigecycline, respectively. All E. faecalis isolates were resistant to QD, while 4 of 62 (6.5%) E. faecium isolates were resistantto QD. All E. faecalis isolates were susceptible to tigecycline, while 14.5% (9/62) E. faecium isolates were resistant. Continuedsurveillance of GRE antibiotic susceptibilities is important for combating these multi-resistant nosocomial pathogens.

Abstract

We investigated the antibiotic susceptibility of glycopeptide-resistant enterococci (GRE). Seventy consecutive GRE were tested. Sixty-two isolates were identified as Enterococcus faecium (88.6%), and 8 (11.4%) as Enterococcus faecalis. All strains weresusceptible to linezolid and daptomycin, while 17.1% (12/70) and 11.4% (8/70) were resistant to quinupristin/dalfopristin (QD)and tigecycline, respectively. All E. faecalis isolates were resistant to QD, while 4 of 62 (6.5%) E. faecium isolates were resistantto QD. All E. faecalis isolates were susceptible to tigecycline, while 14.5% (9/62) E. faecium isolates were resistant. Continuedsurveillance of GRE antibiotic susceptibilities is important for combating these multi-resistant nosocomial pathogens.

참고문헌 (20)

  1. Lautenbach E, "Enterococcal bacteremia:risk factors for vancomycin resistance and predictors of mortality", Infect Control Hosp Epidemiol, 20, pp.318~323 (1999)
  2. DiazGranados CA, "Impact of vancomycin resistance on mortality among patients with neutropenia and enterococcal bloodstream infection", J Infect Dis, 191, pp.588~595 (2005)
  3. Ramsey AM, "Secular trends of hospitalization with vancomycin-resistant enterococcus infection in the United States, 2000-2006", Infect Control Hosp Epidemiol, 30, pp.184~186 (2009)
  4. Yeh KM, "Vancomycin-resistant enterococcus (VRE) carriage and infection in intensive care units", Microb Drug Resist, 10, pp.177~183 (2004)
  5. Dobbs TE, "Nosocomial spread of Enterococcus faecium resistant to vancomycin and linezolid in a tertiary care medical center", J Clin Microbiol, 44, pp.3368~3370 (2006)
  6. Fang H, "Evaluation of species-specific PCR, Bruker MS, VITEK MS and the VITEK 2 system for the identification of clinical Enterococcus isolates", Eur J Clin Microbiol Infect Dis, 31, pp.3073~3077 (2012)
  7. Performance standards for antimicrobial susceptibility testing; Twenty-third informational supplement, "Clinical and Laboratory Standards Institute", CLSI, ~, pp.CLSI Document M100-S23 (2013)
  8. Henwood CJ, "Susceptibility of gram-positive cocci from 25UK hospitals to antimicrobial agents including linezolid. The Linezolid Study Group", J Antimicrob Chemother, 46, pp.931~940 (2000)
  9. Conceição N, "Trends in antimicrobial resistance among clinical isolates of enterococci in a Brazilian tertiary hospital: a 4-year study", Rev Soc Bras Med Trop, 44, pp.177~181 (2011)
  10. Arias CA, "Antibiotic-resistant bugs in the 21st century--a clinical super-challenge", N Engl J Med, 360, pp.439~443 (2009)
  11. Bourdon N, "Changing trends in vancomycin-resistant enterococci in French hospitals, 2001-08", J Antimicrob Chemother, 66, pp.713~721 (2011)
  12. Damani A, "A newly described vancomycin-resistant ST412 Enterococcus faecium predominant in Greek hospitals", Eur J Clin Microbiol Infect Dis, 29, pp.329~331 (2010)
  13. Protonotariou E, "Trends in antimicrobial resistance of clinical isolates of Enterococcus faecalis and Enterococcus faecium in Greece between 2002 and 2007", J Hosp Infect, 75, pp.225~227 (2010)
  14. Deshpande LM, "Antimicrobial resistance and molecular epidemiology of vancomycin-resistant enterococci from North America and Europe: a report from the SENTRY antimicrobial surveillance program", Diagn Microbiol Infect Dis, 58, pp.163~170 (2007)
  15. Sun Y, "The emergence of clinical resistance to tigecycline", Int J Antimicrob Agents, 41, pp.110~116 (2013)
  16. 하남주, "Antimicrobial Activity of Mupirocin, Daptomycin, Linezolid, Quinupristin", Dalfopristin and Tigecycline against Vancomycin-Resistant Enterococci (VRE)from Clinical Isolates in Korea (1998 and 2005), 2007, pp.40(6), 881~887[DOI]
  17. Tsai HY, "Trends in susceptibility of vancomycin-resistant Enterococcus faecium to tigecycline, daptomycin, and linezolid and molecular epidemiology of the isolates: results from the Tigecycline In vitro Surveillance in Taiwan (TIST) study, 2006 to 2010", Antimicrob Agents Chemother, 56, pp.3402~3405 (2012)
  18. Stefani S, "Longitudinal assessment of antimicrobial susceptibility among Gram-negative and Gram-positive organisms collected from Italy as part of the tigecycline evaluation and surveillance trial between 2004 and 2011", Pharmaceuticals (Basel), 6, pp.1381~1406 (2013)
  19. Sader HS, "Daptomycin antimicrobial activity tested against methicillin-resistant staphylococci and vancomycin-resistant enterococci isolated in European medical centers (2005)", BMC Infect Dis, 7, pp.29~ (2007)
  20. Johnson AP, "Activity of daptomycin against multi-resistant Gram-positive bacteria including enterococci and Staphylococcus aureus resistant to linezolid", Int J Antimicrob Agents, 24, pp.315~319 (2004)

관련 논문AI추천

Comparison of Two Quinupristin–dalfopristin Susceptibility Testing Methods and Two Interpretive Criteria for Enterococcus faecium Bloodstream Isolates from Korean HospitalsByun Seung A, Jeong Seok Hoon, Kim Ga-Gyeong, Kim Soo Hyun, Kim Young Ah, Kwon Yong Jun, Lee Ga Yeong, Lim Ha Jin, Shin Jeong Hwan, Shin Jong Hee, Uh Young대한진단검사의학회 · Annals of Laboratory Medicine2025 · 제45권 제6호Does oral doxycycline treatment affect eradication of urine vancomycin-resistant Enterococcus? A tertiary hospital study권기태, 김신우, 이종명, 장현하, Han-Ki Park, Sohyun Bae, Soyoon Hwang, Sujeong Kim, Yoonjung Kim영남대학교 의과대학 · Journal of Yeungnam Medical Science2020 · 제37권 제2호Emergence of optrA-Mediated Linezolid-Nonsusceptible Enterococcus faecalis in a Tertiary Care HospitalHeungsup Sung, Jeonghyun Chang, Kuenyoul Park, Mi-Na Kim, Yun Sil Jeong대한진단검사의학회 · Annals of Laboratory Medicine2020 · 제40권 제4호Successful Treatment of Vancomycin-Resistant Enterococcus species Bone and Joint Infection with Daptomycin Plus Beta Lactam AgentsKim Yong Chan, La Yeonju대한감염학회 · Infection and Chemotherapy2022 · 제54권 제4호Optimizing the Dosing Regimens of Tigecycline against Vancomycin-Resistant Enterococci in the Treatment of Intra-abdominal and Skin and Soft Tissue InfectionsDhitiwat Changpradub, Jatapat Hemapanpairoa, Sudaluck Thunyaharn, Wichai Santimaleeworagun대한감염학회 · Infection and Chemotherapy2020 · 제52권 제3호Vancomycin-Resistant Enterococcus faecium Meningitis Treated with Linezolid: A Case Report and Review of the Literature박성주, 이양근, 이용철, 이창섭, 이흥범대한감염학회 · Infection and Chemotherapy2010 · 제42권 제3호

이 간행물의 다른 논문 (8건)