Aspergillus Tracheobronchitis and Influenza A Co-infection in a Patient with AIDS and Neutropenia
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초록
Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembraneformation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies,neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) areknown to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is onlyone reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patientwith influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. Wepresent a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid useor immunosuppressive therapy.
Abstract
Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembraneformation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies,neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) areknown to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is onlyone reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patientwith influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. Wepresent a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid useor immunosuppressive therapy.
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