Rapidly Fatal Emphysematous Osteomyelitis with Multiple Septic Emboli and Liver Abscess Caused by Klebsiella pneumoniae
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초록
Emphysematous osteomyelitis, characterized by intraosseous gas, is a rare but potentially fatal condition that requires prompt diagnosis and aggressive therapy. Causative organisms are members of the bacterial family Enterobacteriaceae or anaerobes in most cases and significant comorbidities such as diabetes mellitus and malignancy, may predispose an individual to the development of emphysematous osteomyelitis. We report a case of extensive emphysematous osteomyelitis via hematogenous spread from Klebsiella pneumoniae liver abscess, complicated by gas-containing abscesses in adjacent soft tissues and epidural space, and multiple systemic septic emboli in a diabetic patient.
Abstract
Emphysematous osteomyelitis, characterized by intraosseous gas, is a rare but potentially fatal condition that requires prompt diagnosis and aggressive therapy. Causative organisms are members of the bacterial family Enterobacteriaceae or anaerobes in most cases and significant comorbidities such as diabetes mellitus and malignancy, may predispose an individual to the development of emphysematous osteomyelitis. We report a case of extensive emphysematous osteomyelitis via hematogenous spread from Klebsiella pneumoniae liver abscess, complicated by gas-containing abscesses in adjacent soft tissues and epidural space, and multiple systemic septic emboli in a diabetic patient.
참고문헌 (20)
- Ram PC, "CT detection of intraosseous gas: a new sign of osteomyelitis", AJR Am J Roentgenol, 137, pp.721~723 (1981)
- Luey C, "Emphysematous osteomyelitis: a case report and review of the literature", Int J Infect Dis, 16, pp.e216~e220 (2012)
- McDonnell O, "Emphysematous osteomyelitis", JAMA Neurol, 71, pp.512~ (2014)
- Larsen J, "Emphysematous osteomyelitis", Lancet Infect Dis, 15, pp.486~ (2015)
- Chen CW, "Gas-forming vertebral osteomyelitis in diabetic patients", Scand J Infect Dis, 23, pp.263~265 (1991)
- Aghaei Lasboo A, "An unusual appearance of discitis due to gas-forming Escherichia coli with associated pneumocephalus", Spine, 35, pp.E257~E259 (2010)
- Mautone M, "A case of emphysematous osteomyelitis of the midfoot: imaging findings and review of the literature", Case Rep Radiol, 2014, pp.616184~ (2014)
- Jin Hyuk Bang, "Rapidly Progressive Gas-containing Lumbar Spinal Epidural Abscess", Neurospine, 12(3), pp.139~142 (2015), 대한척추신경외과학회[DOI]
- Liao PY, "Rapidly fatal gas-forming pyogenic psoas abscess caused by Klebsiella pneumoniae", Clin Infect Dis, 44, pp.1253~1255 (2007)
- Siu LK, "Klebsiella pneumoniae liver abscess: a new invasive syndrome", Lancet Infect Dis, 12, pp.881~887 (2012)
- Lee HL, "Clinical significance and mechanism of gas formation of pyogenic liver abscess due to Klebsiella pneumoniae", J Clin Microbiol, 42, pp.2783~2785 (2004)
- Yoon JH, "Liver abscess due to Klebsiella pneumoniae: risk factors for metastatic infection", Scand J Infect Dis, 46, pp.21~26 (2014)
- Lin YT, "Klebsiella pneumoniae liver abscess in diabetic patients: association of glycemic control with the clinical characteristics", BMC Infect Dis, 13, pp.56~ (2013)
- Wang HH, "The association of haemoglobin A1C levels with the clinical and CT characteristics of Klebsiella pneumoniae liver abscesses in patients with diabetes mellitus", Eur Radiol, 24, pp.980~989 (2014)
- Jung J, "Comparison of the clinical characteristics and outcomes of Klebsiella pneumoniae and Streptococcus pneumoniae meningitis", Diagn Microbiol Infect Dis, 82, pp.87~91 (2015)
- Fang CT, "Klebsiella pneumoniae genotype K1: an emerging pathogen that causes septic ocular or central nervous system complications from pyogenic liver abscess", Clin Infect Dis, 45, pp.284~293 (2007)
- Kawai T, "Hypermucoviscosity: an extremely sticky phenotype of Klebsiella pneumoniae associated with emerging destructive tissue abscess syndrome", Clin Infect Dis, 42, pp.1359~1361 (2006)
- Yu WL, "Association between rmpA and magA genes and clinical syndromes caused by Klebsiella pneumoniae in Taiwan", Clin Infect Dis, 42, pp.1351~1358 (2006)
- Chung DR, "Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea", J Infect, 54, pp.578~583 (2007)
- Kim JK, "Risk factor analysis of invasive liver abscess caused by the K1 serotype Klebsiella pneumoniae", Eur J Clin Microbiol Infect Dis, 28, pp.109~111 (2009)