제 2형 당뇨병 환아에서 동반된 중증 당뇨병성 케톤산증 1례
A Case of Severe Diabetic Ketoacidosis in a Child with Type 2 Diabetes
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초록
Ketosis-prone diabetes (KPD)는 전형적인 자가면역성 제1형 당뇨병을 포함한 다양한 당뇨병 형태를 포함한다. 최근 비만과 제2형 당뇨병의 빠른 유병율 증가로 제2형 당뇨병이 KPD에서 차지하는 비율의 큰 증가가 예상된다. 지금까지 주로 성인을 대상으로 한 KPD에 대한 연구만 있어 저자는 ketosis-prone 제2형 당뇨병 10세 여아 1례를 문헌 고찰과 함께 보고한다
Abstract
Ketosis-prone diabetes includes heterogeneous disease groups characterized by provoked or unprovoked ketoacidosis (ketosis), with a typical phenotype of autoimmune type 1 diabetes. As the incidence of obesity and type 2 diabetes is universally increasing, the rate of type 2 diabetes in diabetic ketoacidosis in children and adolescents is exptected to increase rapidly. The clinical presentation of atypical ketoacidosis with type 2 diabetes has been reported mostly in adults. We recently experienced a case of a 10-year-old obese girl with new-onset type 2 diabetes who initially presented with severe diabetic ketoacidosis, and introduce it with literature reviews.(J Korean Soc Pediatr Endocrinol 2010;15:46-50)
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