본문 바로가기
KERD
논문KCI 등재

새로 진단된 사춘기 당뇨병 여아의 체성분 분석

Body Composition Analysis in Newly Diagnosed Diabetic Adolescent Girls

2

조회

0

다운로드

3

인용

0

참고문헌

주제분류소아과학

초록

목 적:새로 진단된 사춘기 당뇨병 여아의 성장 상태와 체성분 분석을 통해 당뇨병 형에 따른 차이를 알아보고자 하였다. 방 법:본 연구는 2005년 2월부터 2010년 10월까지 건국대학교병원 소아청소년과에 내원하여 당뇨병이 확진 된 사춘기 당뇨여아 12명을 대상으로 하였다. 연령은 평균 13.0세(9.6- 17.3세) 였고 1형과 2형 당뇨병 각각 6명이었다. 신장과 체중, 체지방 및 제지방을 측정하고 체질량지수, 체지방지수, 제지방지수와 체지방률을 구하였다. 체지방지수와 제지방지수를 이용하여 체성분 차트를 작성하였다. 결 과:2형 당뇨군의 신장 및 체중 z-score는 1형 당뇨군 비교 시 유의한 차이가 없었다. 체질량지수, 제지방지수, 체지방지수와 체지방률 또한 2형 당뇨군에서 높았다. 체성분 차트상 2형 당뇨군은 체지방지수와 체지방률이 현저히 높았으며 1형 당뇨군은 제지방지수가 낮았다. 두 군 간의 체질량지수의 차이는 높은 체지방지수와 낮은 제지방지수에 의해 설명될 수 있다. 결 론:사춘기 여아에서 당뇨병 종류에 따라 체성분에 차이가 있다. 체성분을 측정하는 것은 지속적인 당뇨병 조절의 추적 관리에 유용한 방법이 될 것으로 사료된다.

Abstract

Purpose:The objective of this study was to determine the type differences of diabetes by analyzing the growth status and body composition of newly diagnosed diabetic adolescent girls. Methods:The study included 6 type 1 diabetic adolescent girls (age 11.7±1.9 years) and 6 type 2 diabetic adolescent girls (age 14.4±2.6 years). The height, weight and body composition of fat mass and fat-free mass were measured in each patient. Body mass index (BMI), fat mass index (FMI), fat free mass index (FFMI) and percent body fat (PBF) were calculated and each component was plotted on a body composition chart. Results:Type 2 diabetic adolescent girls seemed to be taller and heavier compared to type 1 diabetic girls, but the differences in height and weight z-score were not significant. BMI, FFMI, FMI, PBF were also higher in type 2 diabetic girls. The body composition chart revealed that type 2 diabetic girls had significantly higher FMI and PBF. In type 1 diabetic girls, FFMI was lower compared to type 2 diabetic girls. The BMI difference between diabetes types was explained with the difference in FFMI as well as FMI. Conclusion:The components of body composition differ according to diabetes type in adolescent girls. Measuring the body composition of diabetic girls might help to promote growth and adequate FFM gain during childhood. In diabetes control, diet and exercise should be emphasized along with insulin treatment.

참고문헌 (34)

  1. Okorodudu DO, "Diagnostic performance of body mass index to identify obesity as defined by body adiposity: a systematic review and meta-analysis", Int J Obes (Lond), 34, pp.791~799 (2010)
  2. Yajnik CS, "The Y-Y paradox", Lancet, 363, pp.163~ (2004)
  3. Maynard LM, "Childhood body composition in relation to body mass index", Pediatrics, 107, pp.344~350 (2001)
  4. 이선영, "Assessment methods in human body composition", CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 11, pp.566~572, LIPPINCORT
  5. "Influence of intensive diabetes treatment on body weight and composition of adults with type 1 diabetes in the diabetes control and complications trial", Diabetes Care, 24, pp.1711~1721 (2001)
  6. Gregory JW, "Body fat and overweight among children and adolescents with diabetes mellitus", Diabet Med, 9, pp.344~348 (1992)
  7. Maharaj S, "Metabolic control in adolescent girls: links to relationality and the female sense of self", Diabetes Care, 27, pp.709~715 (2004)
  8. 문진수, "2007 한국 소아 청소년 성장도표 : 개발 과정과 전망", Korean Journal of Pediatrics, 51(1), pp.1~25 (2008), 대한소아과학회
  9. VanItallie TB, "Height-normalized indices of the body's fat-free mass and fat mass: Potentially useful indicators of nutritional status", Am J Clin Nutr, 52, pp.953~959 (1990)
  10. Hattori K, "Body composition and lean body mass index for Japanese college students", J Anthropol Soc Nippon, 99, pp.141~148 (1991)
  11. Hattori K, "Assessment of body composition by using a new chart method", Am J Hum Biol, 9, pp.573~578 (1997)
  12. 유은경, "소아연령에서 발병된 당뇨병의 병형 및 특성", Korean Journal of Pediatrics, 43(12), pp.1591~1598 (2000), 대한소아과학회
  13. Gillespie KM, "High familial risk and genetic susceptibility in early onset childhood diabetes", Diabetes, 51, pp.210~214 (2002)
  14. Rosenbloom AL, "Distinguishing type 1 and type 2 diabetes at diagnosis. What is the problem", Pediatr Diabetes, 8, pp.51~52 (2007)
  15. Liu LL, "Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for diabetes in youth study", Pediatr Diabetes, 11, pp.4~11 (2010)
  16. Wilkin TJ, "The accelerator hypothesis: Weight gain as the missing link between type I and type II diabetes", Diabetologia, 44, pp.914~922 (2001)
  17. Kliegman RM, "Nelson textbook of pediatrics. 18th ed" (2007), Saunders
  18. Dabelea D, "Testing the accelerator hypothesis: Body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes", Diabetes Care, 29, pp.290~294 (2006)
  19. Jones KL, "Role of obesity in complicating and confusing the diagnosis and treatment of diabetes in children", Pediatrics, 121, pp.361~368 (2008)
  20. Turner R, "UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes", Lancet, 350, pp.1288~1293 (1997), UK prospective diabetes study group
  21. Hathout EH, "Diabetic autoimmune markers in children and adolescents with type 2 diabetes", Pediatrics, 107, pp.E102~ (2001)
  22. 이상아, "한국인 성인 당뇨병환자에서 항 GAD 항체 양성률", Diabetes and Metabolism Journal, 33(1), pp.16~23 (2009), 대한당뇨병학회
  23. Libman IM, "Coexistence of type 1 and type 2 diabetes mellitus: "double" diabetes", Pediatr Diabetes, 4, pp.110~113 (2003)
  24. Reinehr T, "Beta-cell autoantibodies in children with type 2 diabetes mellitus: subgroup or misclassification", Arch Dis Child, 91, pp.473~477 (2006)
  25. Wilkin TJ, "The accelerator hypothesis: a review of the evidence for insulin resistance as the basis for type I as well as type II diabetes", Int J Obes (Lond), 33, pp.716~726 (2009)
  26. Macaluso CJ, "Type 2 diabetes mellitus among florida children and adolescents, 1994 through 1998", Public Health Rep, 117, pp.373~379 (2002)
  27. Mandell F, "The mauriac syndrome", Am J Dis Child, 127, pp.900~902 (1974)
  28. Chiarelli F, "Growth, growth factors and diabetes", Eur J Endocrinol, 151(3), pp.U109~U117 (2004)
  29. Lang T, "Sarcopenia: etiology, clinical consequences, intervention, and assessment", Osteoporos Int, 21, pp.543~559 (2010)
  30. Ellis KJ, "Measuring body fatness in children and young adults: comparison of bioelectric impedance analysis, total body electrical conductivity, and dual-energy X-ray absorptiometry", Int J Obes Relat Metab Disord, 20, pp.866~873 (1996)
  31. Reaven GM, "Role of insulin resistance in human disease", Diabetes, 37, pp.1595~1607 (1988)
  32. Park HG, "A case of metabolic syndrome in a child with normal weight", J Korean Soc Pediatr Endocrinol, 10, pp.115~119 (2005)
  33. Kim TN, "Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes The Korean Sarcopenic Obesity Study (KSOS)", DIABETES CARE, 33(7), pp.1497~1499, AMER DIABETES ASSOC
  34. Schooling CM, "Adolescent build and diabetes: the Guangzhou Biobank Cohort Study", Ann Epidemiol, 21, pp.61~66 (2011)

관련 논문AI추천

이 간행물의 다른 논문 (9건)