전주지역 비만 소아청소년의 갑상선 기능장애
Thyroid Dysfunction in Obese Children in Jeonju, Korea
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목적: 국내 전주지역 소아청소년에서 비만 환아의 갑상선 기능 이상을 확인하고자 하였다. 방법: 2009년도 1월부터 2012년도 9월까지 전북대학교병원 소아내분비 클리닉을 방문한 소아청소년을 대상으로 하여 체질량지수 및 갑상선 호르몬을 측정하고 비만군, 과체중군, 정상체중군의 갑상선 호르몬 차이를 분석하였다. 결과: 비만군의 FT4 값은 16.36±2.84 pmol/L로 과체중군(17.60±2.44 pmol/L)과 정상체중군(17.28±2.35 pmol/L) 에 비해 유의하게 낮았다(P =0.012). 고도비만군의 FT4 값은 15.71±1.68 pmol/L로 경도/중등도 비만군(16.40±2.88 pmol/L) 보다 낮았다. TSH는 비만군, 과체중군, 정상체중군에서 통계적으로 유의한 차이를 보이지 않았다. 결론: 비만인 소아청소년 환아는 정상체중 아동보다 FT4가 낮다.
Abstract
Purpose: The aim of this study was to evaluate thyroid dysfunction in obese children in Korea. Method: We measured body mass index and thyroid hormone in obese, overweight,and normal weight children who visited a pediatric clinic in Jeonju, Korea, from January 2009 to September 2012. Results: The free thyroxoine (FT4) level of the obese group (16.35 ± 2.79 pmol/L) was lower than levels of the overweight (17.65 ± 2.31 pmol/L) and normal weight (17.28 ±2.35 pmol/L; P =0.012) groups. The average value of FT4 in severely obese children (15.71± 1.68 pmol/L) was lower than those of mildly and moderately obese children (16.40 ±2.88 pmol/L). We found no significant difference in thyroid stimulating hormone level between the obese group and normal weight group. Conclusion: The FT4 level is lower in obese children than in normal weight children.
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