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Serum ferritin level is higher in male adolescents with obesity: results from the Korean National Health and Nutrition Examination Survey 2010

김신희|박소현|조원경|정승희|정민호|조경순|정인아|서병규|전연진
대한소아내분비학회 (Korean Society Of Pediatric Endocrinology)|2013.09|Annals of Pediatric Endocrinology & Metabolism|제18권 제3호|pp. 141-147

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키워드

AdolescentKoreanObesityMaleFerritins
주제분류소아과학

초록

Purpose: Previous reports show an association between high serum ferritin levels and metabolic syndrome (MS) in adults. In adolescents, little information is available with obesity and serum ferritin levels. Methods: This is a cross-sectional study. Data were obtained from the 5th Korean National Health and Nutrition Examination Survey (K-NHANES) conducted during 2010by the Korean Ministry of Health and Welfare. A total of 849 subjects aged 10–18 years participated in the 2010 survey. A body mass index (BMI) ≥95th percentile for age and sex or a BMI ≥25 was used to diagnose as obesity. Results: The weighted prevalence of obesity was 13.4% (62/462) in male and 8.5%(33/387) in female. We observed significantly higher serum ferritin in male than in female (mean±standard error [SE], 50.5±2.3 μU/L vs. 30.6±1.3 μU/L; P ＜0.0001). In male, serum ferritin is positively correlated with age (P ＜0.0001). White blood cell (WBC) count, serum fasting blood sugar, triglyceride (TG), total cholesterol, lowdensity lipoprotein, insulin, homeostasis model assessment-insulin resistance (HOMAIR),systolic and diastolic blood pressure, and ferritin levels were higher and highdensity lipoprotein (HDL) were lower in the obesity than in the normal group. In female adolescents, WBC count, TG, insulin, and HOMA-IR were higher and HDL were lower in the obesity than in the normal group. In male, serum ferritin levels showed positive association with obesity (β=21.196, P =0.016). Conclusion: Serum ferritin levels appear to be associated with obesity in Korean male adolescents.

Abstract

Purpose: Previous reports show an association between high serum ferritin levels and metabolic syndrome (MS) in adults. In adolescents, little information is available with obesity and serum ferritin levels. Methods: This is a cross-sectional study. Data were obtained from the 5th Korean National Health and Nutrition Examination Survey (K-NHANES) conducted during 2010by the Korean Ministry of Health and Welfare. A total of 849 subjects aged 10–18 years participated in the 2010 survey. A body mass index (BMI) ≥95th percentile for age and sex or a BMI ≥25 was used to diagnose as obesity. Results: The weighted prevalence of obesity was 13.4% (62/462) in male and 8.5%(33/387) in female. We observed significantly higher serum ferritin in male than in female (mean±standard error [SE], 50.5±2.3 μU/L vs. 30.6±1.3 μU/L; P ＜0.0001). In male, serum ferritin is positively correlated with age (P ＜0.0001). White blood cell (WBC) count, serum fasting blood sugar, triglyceride (TG), total cholesterol, lowdensity lipoprotein, insulin, homeostasis model assessment-insulin resistance (HOMAIR),systolic and diastolic blood pressure, and ferritin levels were higher and highdensity lipoprotein (HDL) were lower in the obesity than in the normal group. In female adolescents, WBC count, TG, insulin, and HOMA-IR were higher and HDL were lower in the obesity than in the normal group. In male, serum ferritin levels showed positive association with obesity (β=21.196, P =0.016). Conclusion: Serum ferritin levels appear to be associated with obesity in Korean male adolescents.

참고문헌 (40)

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