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The treatment of Graves’ disease in children and adolescents

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주제분류소아과학

초록

Graves’ disease (GD) accounts for 10%–15% of thyroid disorders in children and adolescents. The use of antithyroid drugs as the initial treatment option in GD is well accepted. An average two years remission is achieved in about 30% of children treated with antithyroid drugs. However, the optimal treatment duration and the predictive marker of remission after antithyroid drug therapy are still controversial. Additionally, 131 I therapy and surgery are considered the option for treatment in children and adolescents with GD. We review the treatment options for pediatric GD and the possible determinants of remission and relapse on antithyroid drug treatment in children and adolescents.

Abstract

Graves’ disease (GD) accounts for 10%–15% of thyroid disorders in children and adolescents. The use of antithyroid drugs as the initial treatment option in GD is well accepted. An average two years remission is achieved in about 30% of children treated with antithyroid drugs. However, the optimal treatment duration and the predictive marker of remission after antithyroid drug therapy are still controversial. Additionally, 131 I therapy and surgery are considered the option for treatment in children and adolescents with GD. We review the treatment options for pediatric GD and the possible determinants of remission and relapse on antithyroid drug treatment in children and adolescents.

참고문헌 (49)

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관련 논문AI추천

Long-term outcomes of Graves’ disease in children and adolescents receiving antithyroid drugsHwang Jin Soon, Kum Change Dae, Lee Hae Sang, Rho Jung Gi, Seo Young Jun, Shim Young Suk대한소아내분비학회 · Annals of Pediatric Endocrinology & Metabolism2021 · 제26권 제4호Remission in pediatric Graves’ disease treated with antithyroid drug and the risk factors associated with relapseWong Man Yee Shirley, Wong Tsz Wai Catherine대한소아내분비학회 · Annals of Pediatric Endocrinology & Metabolism2022 · 제27권 제4호Effects of short-term potassium iodide treatment for thyrotoxicosis due to Graves disease in children and adolescents이해상, 정경욱, 황진순대한소아내분비학회 · Annals of Pediatric Endocrinology & Metabolism2014 · 제19권 제4호Predictive factors for early response to methimazole in children and adolescents with Graves disease: a single-institute study between 1993 and 2013김민선, 이대열, Sun Mi Hwang대한소아내분비학회 · Annals of Pediatric Endocrinology & Metabolism2016 · 제21권 제2호Efficacy and adverse events related to the initial dose of methimazole in children and adolescents with Graves’ diseaseKim Chan Jong, Lee Hyun Gyung, Yang Eun Mi대한소아내분비학회 · Annals of Pediatric Endocrinology & Metabolism2021 · 제26권 제3호Commentary on “Remission in pediatric Graves’ disease treated with antithyroid drug and the risk factors associated with relapse”Kim Ji Hyun대한소아내분비학회 · Annals of Pediatric Endocrinology & Metabolism2022 · 제27권 제4호

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