본문 바로가기
KERD
논문KCI 등재

당뇨병 유ㆍ무에 따른 척수장애인의 복부지방, 아디포사이토카인 및 대사증후군 위험인자의 비교

Comparison of Abdominal Fat, Adipocytokine, Metabolic Syndrome Risk Factors between Diabetes Group and None-diabetes Group in Individuals with Spinal Cord Injury

장명재|최윤진
한국특수체육학회 (Korean Society Of Adapted Physical Activity)|2010.09|한국특수체육학회지 (Korean Journal of Adapted Physical Activity)|제18권 제3호|pp. 57-70|DOI 10.17006/kjapa.2010.18.3.57

2

조회

0

다운로드

2

인용

0

참고문헌

키워드

복부지방Abdominal fat2형당뇨병대사증후군 위험인자Metabolic syndrome risk factors아디포사이토카인Adipocytokine척수장애Spinal cordTypeⅡ diabetes

초록

본 연구는 성인 남성 척수장애인을 대상으로 제2형 당뇨병 유⋅무에 따른 복부지방, 아디포사이토카인 및 대사증후군 위험인자의 차이를 규명하기 위하여 제2형 당뇨집단 10명, 비당뇨집단 10명으로 구성하여 체중, 복부지방, 체력, 아디포사이토카인, 그리고 대사증후군 위험인자를 비교ㆍ분석하였다. 두 집단의 측정값을 비교⋅분석하기 위해 독립 t-검증을 실시하였다. 그 결과 당뇨 유⋅무에 따른 척수장애인의 체중의 차이는 유의하지 않았으나, TFA와 VFA는 당뇨집단이 유의하게 높게 나타났으며, SFA와 VSR는 비당뇨집단보다 당뇨집단이 높게 나타났다. 또한 당뇨 유⋅무에 따른 척수장애인의 우악력, 좌악력, V· O2peak, HRpeak, 그리고 HRrest는 유의한 차이는 없었다. 그리고 당뇨 유⋅무에 따른 척수장애인의 렙틴과 TNF-α는 유의한 차이는 없었으며, 아디포넥틴은 당뇨집단이 비당뇨집단보다 유의하게 높았다. 또한 대사증후군 위험인자 중 TG, HDL, TG, SBP 및 DBP의 유의한 차이는 없었으나, LDL-C, 공복 혈당, 공복 인슐린, 그리고 HOMAIR은 당뇨집단이 비당뇨집단보다 유의하게 높게 나타났다. 이러한 결과들을 통해 당뇨병 유ㆍ무와 상관없이 두 집단 모두 복부비만의 심각성과 함께 당뇨병이 있는 척수장애인의 고지혈증과 인슐린 저항성의 문제점이 나타났다. 따라서 향후 연구에서는 이러한 척수장애인들의 복부지방의 감소와 혈당 및 지질 감소를 위한 다양한 운동프로그램이 개발 및 적용이 요구된다.

Abstract

Ⅰwas to examine the difference of male diabetic spinal cord individuals' weight, abdominal fat, physical strength, adipocytokine, according to the having typeⅡ diabetes, and metabolic syndrome risk factors. The value of measurement of this research was compared and analyzed from male diabetic spinal cord individuals' two group 20 persons: typeⅡ diabetes group 10 persons and none diabetes group 10persons. I was operated independent t prove in order to compare the value of measurement between the two group. The followings are the summery from this research. 1) The difference of weight of spinal cord injuries, according to the diabetes existence, was not apparent, but the diabetes group's TFA and VFA were high clearly, and diabetes group's SFA and VSR were higher than none diabetes group. 2) There was no difference of right and left grasping power, V· O2peak, HRpeak, and HRrest in individuals with spinal cord injuries, according to the diabetes existence. 3) There was no apparent difference of leptin and TNF-α in individuals with spinal cord injuries, according to the diabetes existence, but diabets group's adiponetin was higher than none diabetes group. 4) There was no apparent difference of TG, HDL, TG, SBP and DBP of spinal cord injured individuals, according to the diabetes existence, but the diabetes group's LDL-C, an empty stomach blood sugar and insulin, and HOMAIR were higher than none diabetes group. From these conclusions, TFA, VFA, LDL-C, an empty blood and insulin, HOMAIR, low adiponetin of male diabetic spinal cord injured person, having typeⅡ diabetes, were higher than none diabetes group.

참고문헌 (47)

  1. 박중열, "한국인 인슐린비의존형 당뇨병 환자의 체중변화양상", 당뇨병, 17, pp.51~58 (1993)
  2. 송경은, "한국인 제2형 당뇨병환자의 인슐린분비능과 인슐린저항성에 따른 임상적 특성", Diabetes and Metabolism Journal, 31(2), pp.123~129 (2007), 대한당뇨병학회
  3. 장상아, "걸음측정계 (보수계)로 알아본 제2형 당뇨병환자의 운동량 분석", Diabetes and Metabolism Journal, 31(2), pp.83~88 (2007), 대한당뇨병학회
  4. 정의달, "노인 제2형 당뇨병환자에서 중심성 비만과 당대사, 지질대사 및 대혈관합병증과의 상관관계", Diabetes and Metabolism Journal, 31(4), pp.343~350 (2007), 대한당뇨병학회
  5. 정일규, "의자 차 트레드밀운동이 척수손상 장애인의 유산소능력 및 심폐능력 개선에 미치는 효과", 한국특수체육학회지, 16(4), pp.1~18 (2008), 한국특수체육학회
  6. 최철수, "고혈당 포도당클램프 기법을 이용한 인슐린분비능의 측정: 정상성인에서 출생체중이 인슐린분비능에 미치는 영향", 당뇨병, 20(2), pp.115~123 (1996)
  7. 한국체육과학연구원, "2007 국민체력 실태조사", ~ (2007)
  8. Justin, Y. J, "Obesity, type 2 DM and exercise in people with SCI: implication of sympathetic nervous system impairment in people with SCI", 연세대학교 체육연구논문집, 11(1), pp.118~144 (2004)
  9. American College of Sports Medicine, "ACSM`s guidelines for exercise testing and prescription" (2006), LWW. PA
  10. Apstein, M. D, "Serum lipids during the first year following acute spinal cord injury", Metablism, 47(4), pp.367~370 (1998)
  11. Bauman, W. A, "Disorders of carbohydrate and lipid metabolism in veterans with paraplegia or quadriplegia: a model of premature aging", Metabolism, 43(6), pp.749~756 (1994)
  12. Bauman, W. A, "The effect of residual neurological deficit on oral glucose tolerance in persons with chronic spinal cord injury", Spinal Cord, 37(11), pp.765~771 (1999)
  13. Bauman, W. A, "Is immobilization associated with an abnormal lipoprotein profile? Observations from a diverse cohort", Spinal Cord, 37(7), pp.485~493 (1999)
  14. Bjorntorp,P, "Portal adipose tissue as a generator of risk factors for cardiovascular disease and diabetes", Arteriosclerosis, 10, pp.493~496 (1990)
  15. Boudou, P, "Absence of exercise-induced variations in adiponectin levels despite decreased abdominal adiposity and improved insulin sensitivity in type 2 diabetic men", European Journal of Endocrinology, 149(5), pp.421~424 (2003)
  16. Buchholz, A. C, "Differences in resting metabolic rate between paraplegic and able-bodied subjects are explained by differences in body composition", American Journal of Clinical Nutrition, 77(2), pp.371~378 (2003)
  17. Ciaraldi, T. P, "Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subject", Diabetes, 51, pp.30~36 (2002)
  18. Cooney, M. M, "Hydraulic resistance exercise benefits cardiovascular fitness of spinal cord injured", Medicine and Science in Sports Exercise, 18, pp.522~525 (1986)
  19. Denke, M. A, "Excess body weight. An underrecognized contributor to high blood cholesterol levels in white American men", Archives of Internal Medicine, 153(9), pp.1093~1103 (1993)
  20. Giannopoulou, I, "Effects of diet and", or exercise on the adipocytokine and inflammatory cytokine levels of postmenpausal women with type2 diabetes, 2005, pp.54(7), 866~875
  21. Guldiken, S, "Visceral fat thickness determined using sltrasonography is associated with anthropometric and clinical parameters of metabolic syndrome", International Journal of Clinical Practice, 60, pp.1576~1581 (2006)
  22. Hotamisligil, G. S, "Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance", Science, 259, pp.87~91 (1993)
  23. Huang, T. S, "The relation of serum leptin to body mass index and to serum cortisol in men with spinal cord injury", Archives of Physical Medicine and Rehabilitation, 81, pp.1582~1586 (2000)
  24. Jeon, J. Y, "Intact sympathetic nervous system is required for leptin effects on resting metabolic rate in people with spinal cord injury", Journal of Clinical Endocrinology and Metabolism, 88(1), pp.402~407 (2003)
  25. Karlsson,A.K, "Insulin resistance and sympathetic function in high spinal cord injury", Spinal Cord, 37(7), pp.494~500 (1999)
  26. Kern, P. A, "The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase", Journal of Clinical Investigation, 95, pp.2111~2119 (1995)
  27. King, M. L, "Exertional hypotension in spinal cord injury", Chest, 106(4), pp.1166~1171 (1994)
  28. Kondo, T, "Effect of exercise on circulating adipokine levels in obese young women", Endocrine Journal, 53(2), pp.189~195 (2006)
  29. Lesley, A. E, "Visceral adipose tissue and the ratio of visceral to subcutaneous adipose tissue are greater in adults with than in those without spinal cord injury, despite matching waist circumferences", American Journal of Clinical Nutrition, 87, pp.600~607 (2008)
  30. Malik, S, "Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults", Circulation, 10(10), pp.1245~1250 (2004)
  31. Manns, P. J, "Fitness, inflammation, and the metabolic syndrome in men with paraplegia", Archives of Physical Medicine and Rehabilitation, 86(6), pp.1176~1181 (2005)
  32. Matthews, D. R, "Homeostasis model assessment: insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man", Diabetologia, 28, pp.412~419 (1985)
  33. Maruyama, S, "Serum leptin level as an indicator to predict the clinical efficacy of troglitazone in patients with type 2 diabetes mellitus", Diabetes Research and Clinical Practice, 53, pp.161~164 (2001)
  34. Maruyama, Y, "Serum leptin, abdominal obesity and the metabolic syndrome in individuals with chronic spinal cord injury", Spinal Cord, 46(7), pp.494~499 (2008)
  35. Myers, J, "Cardiovascular disease in spinal cord injury an overview of prevalence, risk, evaluation and management", American Journal of Physical Medicine & Rehabilitation, 86(2), pp.142~152 (2007)
  36. Nash, M. S, "Reversal of adaptive left ventricular atrophy following electricallystimulated exercise training in human tetraplegics", Paraplegia, 29(9), pp.590~599 (1991)
  37. Nickas, B. J, "Visceral adipose tissue cutoffs associated with metabolic risk factors for coronary heart disease in women", Diabetes Care, 26(5), pp.1413~1420 (2003)
  38. Ofei, F, "Effects of an engineered human anti-TNF-α antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM", Diabetes, 45, pp.881~885 (1996)
  39. Ohlson, L. O, "The influence of body fat distribution on the incidence of diabetes mellitus: 13.5 years of follow-up of the participants in the study of men born in 1913", Diabetes, 34, pp.105~1058 (1985)
  40. Olle, M. M, "Body composition of sedentary and physically active spinal cord injured individuals estimated from total body electrical conductivity", Archives of Physical Medicine and Rehabilitation, 74(7), pp.706~710 (1993)
  41. Pittas. A. G, "adipocytokinees and insulin resistance", Journal of Clinical Endocrinology and Metabolism, 89(2), pp.4474~4452 (2004)
  42. Sedlock, D. A, "Body composition and resting energy expenditure in long term spinal cord injury", Paraplegia, 28(7), pp.448~454 (1990)
  43. Sutbeyaz, S. T, "The combined effects of controlled breathing techniques and ventilatory and upper extremity muscle exercise on cardiopulmonary responses in patients with spinal cord injury", International Journal of Rehabilitation Research, 28, pp.273~276 (2005)
  44. Tudor-Locke, C. E, "Pedometer-determined ambulatory activity in individuals with type 2 diabetes", Diabetes Research and Clinical Practice, 55, pp.191~199 (2002)
  45. Wang, Y. H, "Fasting serum levels of adiponectin, ghrelin, and leptin in men with spinal cord injury", Archives of Physical Medicine and Rehabilitation, 86(10), pp.1964~1968 (2005)
  46. Wilt, T. J, "Carbohydrate and lipid disorders and relevant considerations in persons with spinal cord injury", Evidence Report, 2008, pp.163, 1~95
  47. Zlotolow, S. P, "The serum lipoprotein profile in veterans with paraplegia: The relationship to nutritional factors and body mass index", Journal of the American Paraplegia Society, 15(3), pp.158~162 (1992)

관련 논문AI추천

신체활동에 따른 척수장애인의 비만도 평가김동만, 김인애, 한민규한국특수체육학회 · 한국특수체육학회지2010 · 제18권 제1호척수장애선수들의 운동에 따른 경구 당부하 검사에 대한 당과 인슐린 반응 개선 효과신윤아, 이재원, 이준희, 홍상민한국특수체육학회 · 한국특수체육학회지2020 · 제28권 제2호Factors Affecting Metabolic Syndrome in Individuals With Chronic Spinal Cord InjuryBum-Suk Lee, Ji Won Shin, Onyoo Kim, Tayeon Kim대한재활의학회 · Annals of Rehabilitation Medicine2022 · 제46권 제1호Characteristics of Abdominal Obesity in Persons With Spinal Cord Injury김광동, 남형석, 신형익대한재활의학회 · Annals of Rehabilitation Medicine2013 · 제37권 제3호척수손상비손상인의 신체부위별 신체구성 및 골밀도 비교김성수, 김태수, 양정수, 이동희, 이충일, 황부근한국특수체육학회 · 한국특수체육학회지2003 · 제11권 제1호척수손상인의 일반적 특성에 따른 체력적 특징과 운동 전략신윤아, 이근호, 홍상민한국운동생리학회 · 운동과학2019 · 제28권 제2호

이 간행물의 다른 논문 (11건)

장애인체육 행정전달체계의 개선 방안 연구 - 시군구지부 설립을 중심으로 -강유석, 성문정, 임찬규, 김권일pp. 1-14지적장애 운동수행 프로파일의 타당화김경숙, 김태형pp. 15-31장애인 운동선수의 기본적 심리욕구와 운동지속수행의 인과관계에서 배경변인의 조절효과서은철, 조창옥pp. 33-55특수체육지도자의 스페셜올림픽 참여경험과 교육신념에 관한 연구채규연, 조영희pp. 71-84지적장애인의 작업기억 용량과 집행기능의 부하가 목표지향적 이동 수행에 미치는 영향김동환, 전혜자, 최대원, 이현수pp. 85-94
원문 보기