Change of Ginsenoside Profiles in Processed Ginseng by Drying, Steaming, and Puffing
3
조회
0
다운로드
8
인용
0
참고문헌
키워드
초록
Korean ginseng (Panax ginseng Meyer) was processed by drying, steaming, or puffing, and the effects of these processes on the ginsenoside profile were investigated. The main root of 4-year-old raw Korean ginseng was dried to produce white ginseng. Steaming, followed by drying, was employed to produce red or black ginseng. In addition, these three varieties of processed ginseng were puffed using a rotational puffing gun. Puffed ginseng showed significantly higher extraction yields of ginsenosides (49.87–58.60 g solid extract/100 g of sample) and crude saponin content (59.40–63.87 mg saponin/g of dried ginseng) than nonpuffed ginseng, respectively. Moreover, puffing effectively transformed the major ginsenosides (Rb1, Rb2, Rc, Rd, Re, and Rg1) of ginseng into minor ones (F2, Rg3, Rk1, and Rg5), comparable to the steaming process effect on the levels of the transformed ginsenosides. However, steaming takes much longer (4 to 36 days) than puffing (less than 30 min) for ginsenoside transformation. Consequently, puffing may be an effective and economical technique for enhancing the extraction yield and levels of minor ginsenosides responsible for the major biological activities of ginseng.
Abstract
Korean ginseng (Panax ginseng Meyer) was processed by drying, steaming, or puffing, and the effects of these processes on the ginsenoside profile were investigated. The main root of 4-year-old raw Korean ginseng was dried to produce white ginseng. Steaming, followed by drying, was employed to produce red or black ginseng. In addition, these three varieties of processed ginseng were puffed using a rotational puffing gun. Puffed ginseng showed significantly higher extraction yields of ginsenosides (49.87–58.60 g solid extract/100 g of sample) and crude saponin content (59.40–63.87 mg saponin/g of dried ginseng) than nonpuffed ginseng, respectively. Moreover, puffing effectively transformed the major ginsenosides (Rb1, Rb2, Rc, Rd, Re, and Rg1) of ginseng into minor ones (F2, Rg3, Rk1, and Rg5), comparable to the steaming process effect on the levels of the transformed ginsenosides. However, steaming takes much longer (4 to 36 days) than puffing (less than 30 min) for ginsenoside transformation. Consequently, puffing may be an effective and economical technique for enhancing the extraction yield and levels of minor ginsenosides responsible for the major biological activities of ginseng.
참고문헌 (32)
- Park JS, "Anti-inflammatory mechanism of ginseng saponins in activated microglia", J. Neuroimmunol, 209, pp.40~49 (2009)
- Cho WCS, "Ginsenoside Re of Panax ginseng possesses significant antioxidant and antihyperlipidemic efficacies in streptozotocin-induced diabetic rats", Eur. J. Pharmacol, 550, pp.173~179 (2006)
- Xie J-T, "Anti-diabetic effect of ginsenoside Re in ob", ob mice, 2005, pp.1740, 319~325
- Park E-K, "Ginsenoside Rh1 possesses antiallergic and anti-inflammatory activities", Int. Arch. Allergy Immunol, 133, pp.113~120 (2004)
- 신지연, "Anti-Cancer Effect of Ginsenoside F2 against Glioblastoma Multiforme in Xenograft Model in SD Rats", Journal of Ginseng Research, 36(1), pp.86~92 (2012), 고려인삼학회
- Qu C, "Study on ginsenosides in different parts and ages of Panax quinquefolius L", Food Chem, 115, pp.340~346 (2009)
- Yu H, "A new ginsenosidase from Aspergillus strain hydrolyzing 20-Omulti-glycoside of PPD ginsenoside", Process Biochem, 44, pp.772~775 (2009)
- Cheng L-Q, "Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp, GS514", Phytochemistry, 69, pp.218~224 (2008)
- Shinkai K, "Inhibition of in vitro tumor cell invasion by ginsenoside Rg3", Jpn. J. Cancer Res, 87, pp.357~362 (1996)
- Lee H-U, "Hepatoprotective effect of 20(S)-ginsenosides Rg3 and its metabolite 20(S)-ginsenoside Rh2 on tert-butyl hydroperoxide-induced liver injury", Biol. Pharm. Bull, 28, pp.1992~1994 (2005)
- Wei X, "Stereospecificity of ginsenoside Rg3 in promotion of the immune response to ovalbumin in mice", Int. Immunol, 24, pp.465~471 (2012)
- Tian J, "20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain", Phytother. Res, 23, pp.486~491 (2009)
- Lee Y, "A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells", J. Steroid Biochem. Mol. Biol, 84, pp.463~468 (2003)
- 전림호, "Lactobacillus brevis LH8이 생산하는 효소에 의한 Ginsenoside Rd의 Compound K로의 전환", Journal of Ginseng Research, 32(3), pp.226~231 (2008), 고려인삼학회
- Sun BS, "Simultaneous quantification of 19 ginsenosides in black ginseng developed from Panax ginseng by HPLC-ELSD", J. Pharm. Biomed. Anal, 50, pp.15~22 (2009)
- Kang KS, "Therapeutic potential of 20(S)-ginsenoside Rg3 against streptozotocin-induced diabetic renal damage in rats", Eur. J. Pharmacol, 591, pp.266~272 (2008)
- Chen J, "Research on the antitumor effect of ginsenoside Rg3 in B16 melanoma cells", Melanoma Res, 18, pp.322~329 (2008)
- Taddessee Yayeh, "Korean Red Ginseng Saponin Fraction Downregulates Proinfl ammatory Mediators in LPS Stimulated RAW264.7 Cells and Protects Mice against Endotoxic Shock", Journal of Ginseng Research, 36(3), pp.263~269 (2012), 고려인삼학회
- Kim J H, "B lack ginseng extract counteracts streptozotocin-induced diabetes in mice", PLoS One, 11, pp.e0146843~ (2016)
- Payne FA, "A review of puffing processes for expansion of biological products", J. Food Eng, 10, pp.183~197 (1989)
- An Y-E, "Chemical conversion of ginsenosides in puffed red ginseng", LWT-Food Sci. Technol, 44, pp.370~374 (2011)
- Shim KS, "Effects of puffing treatments on the sensory qualities improving of ginseng extract", J, Korean Prof. Eng. Assoc, 33, pp.106~115 (2000)
- 백무열, "팽화에 의한 인삼 유효성분의 변화", Applied Biological Chemistry, 51(3), pp.188~193 (2008), 한국응용생명화학회
- 하대철, "홍삼·백삼 및 압출성형 건조수삼의 성분특성", 한국식품영양과학회지, 34(2), pp.247~254 (2005), 한국식품영양과학회
- 이지현, "흑삼의 제조 및 항암효과", 동의생리병리학회지, 20(4), pp.951~956 (2006), 한의병리학회
- Ando T, "Chemical studies on the oriental plant drugs (XXV), Comparative studies on the saponins and sapogenins of ginseng and related crude drugs", Shoyakugaku Zasshi, 25, pp.28~32 (1971)
- Sun B-S, "Simultaneous quantification of 19 ginsenosides in black ginseng developed from Panax ginseng by HPLC–ELSD", J. Pharm. Biomed. Anal, 50, pp.15~22 (2009)
- Du XW, "Changes in neutral and malonyl ginsenosides in American ginseng(Panax quinquefolium)during drying, storage and ethanolic extraction", Food Chem, 86, pp.155~159 (2004)
- Kim WY, "Steaming of ginseng at high temperature enhances biological activity", J. Nat. Prod, 63, pp.1702~1704 (2000)
- Kang KS, "Stereospecificity in hydroxyl radical scavenging activities of four ginsenosides produced by heat processing", Bioorg. Med. Chem. Lett, 16, pp.5028~5031 (2006)
- Mariotti M, "Effect of puffing on ultrastructure and physical characteristics of cereal grains and flours", J. Cereal Sci, 43, pp.47~56 (2006)
- Sung-Ran Yoon, "Monitoring of Chemical Changes in Explosively Puffed Ginseng and the Optimization of Puffing Conditions", Journal of Ginseng Research, 34(1), pp.59~67 (2010), 고려인삼학회
