Metabolomic Investigation on Fermentation Products of Achyranthes japonica Nakai by Lactobacillus plantarum
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Fermentation has recently re-emerged as an approach for improved functionality of food products in addition to the traditional roles such as shelf life, taste, and texture. Here, we report dynamic changes in the metabolite profiles of Achyranthes japonica Nakai by Lactobacillus plantarum fermentation, primarily, the significant increases in representative functional ingredients, 20-hydroxyecdysone and 25S-inokosterone. Additionally, untargeted metabolite profiling showed 58% of metabolites underwent significant alteration. The most dynamic change was observed in cellobiose, which showed a 56-fold increase. Others were sugar alcohols and amino acids, while lyxitol and erythritol that were among the most dynamically down-regulated.
Abstract
Fermentation has recently re-emerged as an approach for improved functionality of food products in addition to the traditional roles such as shelf life, taste, and texture. Here, we report dynamic changes in the metabolite profiles of Achyranthes japonica Nakai by Lactobacillus plantarum fermentation, primarily, the significant increases in representative functional ingredients, 20-hydroxyecdysone and 25S-inokosterone. Additionally, untargeted metabolite profiling showed 58% of metabolites underwent significant alteration. The most dynamic change was observed in cellobiose, which showed a 56-fold increase. Others were sugar alcohols and amino acids, while lyxitol and erythritol that were among the most dynamically down-regulated.
참고문헌 (8)
- Bing Tian Zhao, "High Performance Liquid Chromatography used for Quality Control of Achyranthis Radix", Archives of Pharmacal Research, 35(8), pp.1449~1455 (2012), 대한약학회[DOI]
- Filannino P, "Metabolic and functional paths of lactic acid bacteria in plant foods : get out of the labyrinth", Curr. Opin. Biotechnol, 49, pp.64~72 (2018)
- Zhao D, "Lactic acid bacterial fermentation modified phenolic composition in tea extracts and enhanced their antioxidant activity and cellular uptake of phenolic compounds following in vitro digestion", J. Funct. Foods, 20, pp.182~194 (2016)
- Jung S, "Inhibitory effects of three oleanolic acid glycosides from Achyranthes japonica on the complement classical pathway", Immunopharmacol. Immunotoxicol, 34, pp.213~215 (2012)
- Lee SG, "Anti-inflammatory and anti-osteoarthritis effects of fermented Achyranthes japonica Nakai", J. Ethnopharmacol, 142, pp.634~641 (2012)
- Tao Y, "Determination of major components from Radix Achyranthes bidentate using ultra high performance liquid chromatography with triple quadrupole tandem mass spectrometry and an evaluation of their anti-osteoporosis effect in vitro", J. Sep. Sci, 42, pp.2214~2221 (2019)
- Lee DY, "High quality metabolomic data for Chlamydomonas reinhardtii", Plant Methods, 4, pp.7~ (2008)
- Nakagawa Y, "20-Hydroxyecdysone. Handbook of Hormones", Comparative Endocrinology for Basic and Clin. Res., 2, pp.560~563 (2016)