Echinacoside Induces UCP1- and ATPDependent Thermogenesis in Beige Adipocytes via the Activation of Dopaminergic Receptors

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참고문헌 (55)

1. Gaspar RC, "An update on brown adipose tissue biology: a discussion of recent findings", Am. J. Physiol. Endocrinol. Metab, 320, pp.E488~E495 (2021)
2. Zhang P, "Factors associated with white fat browning: new regulators of lipid metabolism", Int. J. Mol. Sci, 23, pp.7641~ (2022)
3. Ruprecht JJ, "The SLC25 mitochondrial carrier family: structure and mechanism", Trends Biochem. Sci, 45, pp.244~258 (2020)
4. Fedorenko A, "Mechanism of fatty-acid-dependent UCP1 uncoupling in brown fat mitochondria", Cell, 151, pp.400~413 (2012)
5. Ikeda K, "UCP1-independent signaling involving SERCA2bmediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis", Nat. Med, 23, pp.1454~1465 (2017)
6. Chang SH, "Mechanisms underlying UCP1 dependent and independent adipocyte thermogenesis", Obes. Rev, 20, pp.241~251 (2019)
7. Fuller-Jackson JP, "Adipose and skeletal muscle thermogenesis: studies from large animals", J. Endocrinol, 237, pp.R99~R115 (2018)
8. Calixto JB, "The role of natural products in modern drug discovery", An. Acad. Bras. Cienc, 91, pp.e20190105~ (2019)
9. Choi Y, "Natural bioactive compounds as potential browning agents in white adipose tissue", Pharm. Res, 38, pp.549~567 (2021)
10. Veeresham C, "Natural products derived from plants as a source of drugs", J. Adv. Pharm. Technol. Res, 3, pp.200~ (2012)
11. Lee MK, "Natural extracts that stimulate adipocyte browning and their underlying mechanisms", Antioxidants, 10, pp.308~ (2021)
12. Shiao YJ, "Echinacoside ameliorates the memory impairment and cholinergic deficit induced by amyloid beta peptides via the inhibition of amyloid deposition and toxicology", Food Funct, 8, pp.2283~2294 (2017)
13. Liu J, "Echinacoside, an inestimable natural product in treatment of neurological and other disorders", Molecules, 23, pp.1213~ (2018)
14. Chen C, "Echinacoside protects against MPTP", MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1, 2019, pp.34, 203~212
15. Zhang X, "Beneficial effects of echinacoside on diabetic cardiomyopathy in diabetic Db", Db mice, 2020, pp.18, 5575~5587
16. Chuang HW, "Echinacoside exhibits antidepressant-like effects through AMPAR–Akt", ERK–mTOR pathway stimulation and BDNF expression in mice, 2022, pp.17, 9~
17. Zhang Y, "Echinacoside promotes the proliferation of human renal tubular epithelial cells by blocking the HBX", TREM2-mediated NF-κB signalling pathway, 2020, pp.22, 1137~1144
18. Jiang Z, "Echinacoside increases sperm quantity in rats by targeting the hypothalamic androgen receptor", Sci. Rep, 8, pp.3839~ (2018)
19. Ni Y, "Echinacoside reverses myocardial remodeling and improves heart function via regulating SIRT1", FOXO3a, J. Cell. Mol. Med, pp.2021, 25[DOI]
20. Jia C, "Metabolism of echinacoside, a good antioxidant, in rats: isolation and identification of its biliary metabolites", Drug Metab. Dispos, 37, pp.431~438 (2009)
21. Shu W, "Exploration of the effect and potential mechanism of echinacoside against endometrial cancer based on network pharmacology and in vitro experimental verification", Drug Des. Devel. Ther, 16, pp.1847~1863 (2022)
22. Ni Y, "Echinacoside inhibited cardiomyocyte pyroptosis and improved heart function of HF rats induced by isoproterenol via suppressing NADPH", ROS, J. Cell. Mol. Med, pp.2022, 26[DOI]
23. Jiang T, "Echinacoside inhibits osteoclast function by down-regulating PI3K", Akt, Front. Pharmacol, pp.2022, 13[DOI]
24. Nematalla KM, "Effect of echinacea as antioxidant on markers of aging", Aust. J. Basic Appl. Sci, 5, pp.18~26 (2011)
25. Kim HR, "Immune enhancing effects of Echinacea purpurea root extract by reducing regulatory T cell number and function", Nat. Prod. Commun, 9, pp.1934578X1400900422~ (2014)
26. Pham HG, "Salvianolic acid B induces browning in 3T3-L1 white adipocytes via activation of β3-AR and ERK signaling pathways", J. Funct. Foods, 81, pp.104475~ (2021)
27. Mukherjee S, "β-Carotene stimulates browning of 3T3-L1 white adipocytes by enhancing thermogenesis via the β3-AR", p38 MAPK, Phytomedicine, pp.2022, 96[DOI]
28. Kim E, "The impact of phytochemicals in obesity-related metabolic diseases: focus on ceramide metabolism", Nutrients, 15, pp.703~ (2023)
29. Wu L, "AMP-activated protein kinase (AMPK) regulates energy metabolism through modulating thermogenesis in adipose tissue", Front. Physiol, 9, pp.122~ (2018)
30. Fullerton MD, "Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulinsensitizing effects of metformin", Nat. Med, 19, pp.1649~1654 (2013)
31. London E, "PKA functions in metabolism and resistance to obesity: lessons from mouse and human studies", J. Endocrinol, 246, pp.R51~ (2020)
32. Ikeda K, "The common and distinct features of brown and beige adipocytes", Trends Endocrinol. Metab, 29, pp.191~200 (2018)
33. Shi F, "Second messenger signaling mechanisms of the brown adipocyte thermogenic program: an integrative perspective", Horm. Mol. Biol. Clin. Investig, 31(2) (2017)[DOI]
34. Leiva M, "Uncovering the role of p38 family members in adipose tissue physiology", Front. Endocrinol, 11, pp.572089~ (2020)
35. Kiros Haddish, "L-Dihydroxyphenylalanine (L-Dopa) Induces Brown-like Phenotype in 3T3-L1 White Adipocytes via Activation of Dopaminergic and β3-adrenergic Receptors", Biotechnology and Bioprocess Engineering, 27(5), pp.792~806 (2022), 한국생물공학회[DOI]
36. Haddish K, "Dopaminergic and adrenergic receptors synergistically stimulate browning in 3T3-L1 white adipocytes", J. Physiol. Biochem, 79, pp.117~131 (2023)
37. Sandoval-Avila S, "Neuroprotective effects of phytochemicals on dopaminergic neuron cultures", Neurologia, 34, pp.114~124 (2019)
38. Kempster, P, "Parkinson’s disease, dopaminergic drugs and the plant world", Front. Pharmacol, 13, pp.970714~ (2022)
39. Luedtke RR, "Pharmacological survey of medicinal plants for activity at dopamine receptor subtypes. II. Screen for binding activity at the D1 and D2 dopamine receptor subtypes", Pharm. Biol, 41, pp.45~58 (2003)
40. Popov LD, "Mitochondrial biogenesis: an update", J. Cell. Mol. Med, 24, pp.4892~4899 (2020)
41. Heinonen S, "Impaired mitochondrial biogenesis in adipose tissue in acquired obesity", Diabetes, 64, pp.3135~3145 (2015)
42. Mishra A, "Dopamine receptor activation mitigates mitochondrial dysfunction and oxidative stress to enhance dopaminergic neurogenesis in 6-OHDA lesioned rats: a role of Wnt signalling", Neurochem. Int, 129, pp.104463~ (2019)
43. Kohlie R, "Dopamine directly increases mitochondrial mass and thermogenesis in brown adipocytes", J. Mol. Endocrinol, 58, pp.57~66 (2017)
44. Chen S, "Dopamine inhibits mitochondrial motility in hippocampal neurons", PLoS One, 3, pp.e2804~ (2008)
45. Haddish K, "Dopamine receptor D4 (DRD4) negatively regulates UCP1- and ATP-dependent thermogenesis in 3T3-L1 adipocytes and C2C12 muscle cells", Pflugers Arch, 475, pp.757~773 (2023)
46. Haddish K, "Silencing of dopamine receptor D5 inhibits the browning of 3T3-L1 adipocytes and ATP-consuming futile cycles in C2C12 muscle cells", Arch. Physiol. Biochem, 4, pp.1~13 (2023)
47. Wallimann T, "Role of creatine and creatine kinase in UCP1-independent adipocyte thermogenesis", Am. J. Physiol. Endocrinol. Metab, 319, pp.E944~E946 (2020)
48. Ikeda, K, "UCP1 dependent and independent thermogenesis in brown and beige adipocytes", Front. Endocrinol, 11, pp.498~ (2020)
49. Brownstein AJ, "ATP-consuming futile cycles as energy dissipating mechanisms to counteract obesity", Rev. Endocr. Metab. Disord, 23, pp.121~131 (2022)
50. Szanda G, "Participation of p38 MAPK and a novel-type protein kinase C in the control of mitochondrial Ca2+ uptake", Cell Calcium, 43, pp.250~259 (2008)
51. Song Z, "Calcium signaling pathways: key pathways in the regulation of obesity", Int. J. Mol. Sci, 20, pp.2768~ (2019)
52. Sander P, "A calcium guard in the outer membrane: is VDAC a regulated gatekeeper of mitochondrial calcium uptake?", Int. J. Mol. Sci, 22, pp.946~ (2021)
53. Lezcano N, "D1", D5 dopamine receptors stimulate intracellular calcium release in primary cultures of neocortical and hippocampal neurons, 2002, pp.87, 2167~2175
54. Surmeier DJ, "Modulation of calcium currents by a D1 dopaminergic protein kinase", phosphatase cascade in rat neostriatal neurons, 1995, pp.14, 385~397
55. Chaudhuri D, "MCU encodes the pore conducting mitochondrial calcium currents", eLife, 2, pp.e00704~ (2013)

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