당뇨병이 없는 알코올중독 환자에서 광범위한 뇌병변을 보인 저혈당성 뇌병증 1예
A Case of Severe Hypoglycemic Encephalopathy with Extensive Brain Lesions in Non-diabetics and Alcoholism
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Hypoglycemic encephalopathy is a rare problem among diabetic patients who are receiving treatment with insulin or other glucose-lowering drugs. The MRIs of patients with hypoglycemic encephalopathy commonly show scattered lesions in the cerebral cortex, hippocampus and basal ganglia, but lesions in the cerebellum or brain stem are extremely rare. A 44-year-old alcoholic woman without diabetes was admitted with a semicomatose mentality and seizure with severe hypoglycemic encephalopathy with extensive brain lesions seen on MRI at the middle cerebellar peduncle and midbrain, as well as in the other brain areas.
Abstract
Hypoglycemic encephalopathy is a rare problem among diabetic patients who are receiving treatment with insulin or other glucose-lowering drugs. The MRIs of patients with hypoglycemic encephalopathy commonly show scattered lesions in the cerebral cortex, hippocampus and basal ganglia, but lesions in the cerebellum or brain stem are extremely rare. A 44-year-old alcoholic woman without diabetes was admitted with a semicomatose mentality and seizure with severe hypoglycemic encephalopathy with extensive brain lesions seen on MRI at the middle cerebellar peduncle and midbrain, as well as in the other brain areas.
참고문헌 (10)
- Auer RN, "Progress review: hypoglycemic brain damage", Stroke, 17(4), pp.699~708 (1986)
- Finelli PF, "Diffusion-weighted MR in hypoglycemic coma", Neurology, 57(5), pp.933~935 (2001)
- Lo L, "Diffusionweighted MR imaging in early diagnosis and prognosis of hypoglycemia", Am J Neuroradiol, 27(6), pp.1222~1224 (2006)
- 지명구, "자기공명영상에서 지연성 병변을 보인저혈당성 뇌병증", 대한신경과학회지, 26(3), pp.263~266 (2008), 대한신경과학회
- Fujioka M, "Specific change in human brain after hypoglycemic injury", Stroke, 28(3), pp.574~577 (1997)
- Hasegawa Y, "Severe transient hypoglycemia causes reversible change in the apparent diffusion coefficient of water", Stroke, 27(9), pp.1648~1655 (1996)
- Suh SW, "Hypoglycemia, brain energetics, and hypoglycemic neuronal death", Glia, 55(12), pp.1280~1286 (2007)
- LaManna JC, "Regional comparisons of brain glucose influx", Brain Res, 326(2), pp.299~305 (1985)
- Engelhorn T, "Monitoring of acute generalized status epilepticus using multilocal diffusion MR imaging: early prediction of regional neuronal damage", Am J Neuroradiol, 28(2), pp.321~327 (2007)
- Huang Z, "Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via nitric oxide and vagally mediated mechanisms", Endocrinology, 149(1), pp.232~236 (2008)