종격동 내 발생한 활막 육종 1예
A Case of Synovial Sarcoma in Mediastinum
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초록
Synovial sarcoma is a rare malignancy in the thoracic cavity, especially in the mediastinum. In this paper, a case of primary mediastinal synovial sarcoma is reported. A 34-year-old woman was hospitalized with dyspnea. Her chest X-ray and computed tomography (CT) showed a 16×13×11 cm mass in her anterior mediastinal space. Surgical resection was performed but was incomplete. The pathological and immunohistochemical analysis confirmed the diagnosis of monophasic spindle cell synovial sarcoma. The patient underwent adjuvant radiotherapy for two months, but local recurrence and metastasis occurred in her pleural cavity. She eventually underwent chemotherapy for one year and died 18 months after her operation.
Abstract
Synovial sarcoma is a rare malignancy in the thoracic cavity, especially in the mediastinum. In this paper, a case of primary mediastinal synovial sarcoma is reported. A 34-year-old woman was hospitalized with dyspnea. Her chest X-ray and computed tomography (CT) showed a 16×13×11 cm mass in her anterior mediastinal space. Surgical resection was performed but was incomplete. The pathological and immunohistochemical analysis confirmed the diagnosis of monophasic spindle cell synovial sarcoma. The patient underwent adjuvant radiotherapy for two months, but local recurrence and metastasis occurred in her pleural cavity. She eventually underwent chemotherapy for one year and died 18 months after her operation.
참고문헌 (10)
- Essary LR, "Primary pleuropulmonary synovial sarcoma: reappraisal of a recently described anatomic subset", Cancer, 94, pp.459~469 (2002)
- Ferrari A, "Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution", Cancer, 101, pp.627~634 (2004)
- Hartel PH, "Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series", Mod Pathol, 20, pp.760~769 (2007)
- 박재석, "Primary Pulmonary Biphasic Synovial Sarcoma Confirmed by Molecular Detection of a SYT-SSX2 Fusion Gene: Report of 1 Case", The Korean Journal of Internal Medicine, 25(3), pp.331~336 (2010), 대한내과학회
- Lee HJ, "Primary mediastinal synovial sarcoma", J Lung Cancer, 7, pp.29~33 (2008)
- Bae CH, "Primary synovial sarcoma in the mediastinum: a case report", Korean J Thorac Cardiovasc Surg, 34, pp.437~440 (2001)
- Henninger B, "Primary mediastinal synovial sarcoma: a case report and review of the literature", Cases J, 2, pp.6948~ (2009)
- Lewis JJ, "Synovial sarcoma: a multivariate analysis of prognostic factors in 112 patients with primary localized tumors of the extremity", J Clin Oncol, 18, pp.2087~2094 (2000)
- Ladanyi M, "Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients", Cancer Res, 62, pp.135~140 (2002)
- Spillane AJ, "Synovial sarcoma: a clinicopathologic, staging, and prognostic assessment", J Clin Oncol, 18, pp.3794~3803 (2000)