Annual Neck Ultrasonography Surveillance between 3 to 12 Years after Thyroid Lobectomy for Papillary Thyroid Microcarcinoma
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Background and Objectives: In South Korea, neck ultrasonography (US) has been used widely at 1- or 2-yearintervals to detect recurrence after thyroidectomy. The aim of this study is to assess the prevalence and patternof recurrence and to establish a proper frequency of follow-up neck US after thyroid lobectomy for papillary thyroidmicrocarcinoma (PTMC). Materials and Methods: We retrospectively reviewed 262 consecutive patients who hadundergone thyroid lobectomy for PTMC from January 2005 to October 2009. They were divided into two groupsbased on the presence of recurrence (240 patients in group 1 and 22 patients in group 2). The comparisonbetween the two groups involved clinical and pathological characteristics. Results: Recurrences were found in 22(8.4%) of 262 patients with 132.5 months follow-up (range, 120-180 months). There was a significant differencein the mean number of follow-up neck US after 5 years postoperatively, shortened interval, total number offollow-up neck US (p=0.002, p＜0.001, p＜0.001). All recurrences were found between 2-3 to 11-12 years. Recurrences after 5 years were found in 16 (72.7%) of 22 patients. Conclusion: Recurrence after thyroid lobectomyfor PTMC occurred with various times during follow up. The minimum frequency of follow-up neck US was notenough for detecting tumor recurrence, especially after 5 years postoperatively. Our results suggest that annualneck US may be appropriate between 3 to 12 years after thyroid lobectomy for PTMC.
Abstract
Background and Objectives: In South Korea, neck ultrasonography (US) has been used widely at 1- or 2-yearintervals to detect recurrence after thyroidectomy. The aim of this study is to assess the prevalence and patternof recurrence and to establish a proper frequency of follow-up neck US after thyroid lobectomy for papillary thyroidmicrocarcinoma (PTMC). Materials and Methods: We retrospectively reviewed 262 consecutive patients who hadundergone thyroid lobectomy for PTMC from January 2005 to October 2009. They were divided into two groupsbased on the presence of recurrence (240 patients in group 1 and 22 patients in group 2). The comparisonbetween the two groups involved clinical and pathological characteristics. Results: Recurrences were found in 22(8.4%) of 262 patients with 132.5 months follow-up (range, 120-180 months). There was a significant differencein the mean number of follow-up neck US after 5 years postoperatively, shortened interval, total number offollow-up neck US (p=0.002, p＜0.001, p＜0.001). All recurrences were found between 2-3 to 11-12 years. Recurrences after 5 years were found in 16 (72.7%) of 22 patients. Conclusion: Recurrence after thyroid lobectomyfor PTMC occurred with various times during follow up. The minimum frequency of follow-up neck US was notenough for detecting tumor recurrence, especially after 5 years postoperatively. Our results suggest that annualneck US may be appropriate between 3 to 12 years after thyroid lobectomy for PTMC.
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