장기적인 TSH 억제가 심혈관계에 미치는 영향
Effect of Prolonged TSH Suppression on Cardiovascular System
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초록
Prolonged thyroid-stimulating hormone (TSH) suppression caused by exogenous subclinical thyrotoxicosis has been reported to impose harmful effects on cardiovascular system. Those effects involve increase in heart rate and myocardial mass, impaired ventricular diastolic and systolic function, decreased exercise capacity,decreased arterial elasticity, development of atrial tachyarrhythmia, and increase in cardiovascular adverse events. Tailored dose adjustment of thyroid hormone under the guidance of TSH level for obviating oversuppression of TSH, and use of beta blockers can reduce cardiovascular adverse effects in patients who undergo thyroid hormone therapy.
Abstract
Prolonged thyroid-stimulating hormone (TSH) suppression caused by exogenous subclinical thyrotoxicosis has been reported to impose harmful effects on cardiovascular system. Those effects involve increase in heart rate and myocardial mass, impaired ventricular diastolic and systolic function, decreased exercise capacity,decreased arterial elasticity, development of atrial tachyarrhythmia, and increase in cardiovascular adverse events. Tailored dose adjustment of thyroid hormone under the guidance of TSH level for obviating oversuppression of TSH, and use of beta blockers can reduce cardiovascular adverse effects in patients who undergo thyroid hormone therapy.
참고문헌 (16)
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