비전형적인 증상을 주소로 내원한 그레이브스병 환자 2예
Two Cases of Graves’ Disease Presented with Atypical Symptoms
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We describe here two Graves’ patients who have presented with atypical symptoms. Interestingly, both of them had symptoms related to imbalance of body fluid homeostasis. Chief complaint of a 35-year-old woman (case 1) was the ipsilateral edema of upper body. A 33-year-old man (case 2) who had severe polyuria has referred from urology department with impression of diabetes insipidus. Both of them denied any typical symptoms of Graves’ disease at presentation. These rare extrathyroid manifestations of Graves’ disease were completely subsided after antithyroid drug treatment. We introduce their clinical courses and possible pathophysiological mechanisms of the atypical symptoms of Graves’ disease.
Abstract
We describe here two Graves’ patients who have presented with atypical symptoms. Interestingly, both of them had symptoms related to imbalance of body fluid homeostasis. Chief complaint of a 35-year-old woman (case 1) was the ipsilateral edema of upper body. A 33-year-old man (case 2) who had severe polyuria has referred from urology department with impression of diabetes insipidus. Both of them denied any typical symptoms of Graves’ disease at presentation. These rare extrathyroid manifestations of Graves’ disease were completely subsided after antithyroid drug treatment. We introduce their clinical courses and possible pathophysiological mechanisms of the atypical symptoms of Graves’ disease.
참고문헌 (10)
- 이가희, "갑상선기능항진증의 진단 및 치료- 대한갑상선학회 합의안", International Journal of Thyroidology, 6(1), pp.1~11 (2013), 대한갑상선학회
- Friedman IH, "Edema as a presenting symptom of hyperthyroidism", N Y State J Med, 65, pp.1798~1801 (1965)
- Volke V, "Unilateral pitting edema of the leg as a manifestation of Graves' disease: a case report", J Med Case Rep, 6, pp.258~ (2012)
- Wang Y, "Unilateral gynecomastia and hypokalemic periodic paralysis as first manifestations of Graves' disease", Am J Med Sci, 345(6), pp.504~506 (2013)
- Davies TF, "Trauma and pressure explain the clinical presentation of the Graves' disease triad", Thyroid, 10(8), pp.629~630 (2000)
- Rapoport B, "Elephantiasic pretibial myxedema: insight into and a hypothesis regarding the pathogenesis of the extrathyroidal manifestations of Graves' disease", Thyroid, 10(8), pp.685~692 (2000)
- Alsanea O, "Treatment of Graves' disease: the advantages of surgery", Endocrinol Metab Clin North Am, 29(2), pp.321~337 (2000)
- Savino W, "Neuroendocrine control of thymus physiology", Endocr Rev, 21(4), pp.412~44 (2000)
- Yamazaki M, "Transient polyuria related to central diabetes insipidus caused by lymphocytic infundibulo-neurohypophysitis in a patient treated for Graves' disease", Intern Med, 49(17), pp.1885~1890 (2010)
- Evered DC, "Primary polydipsia in thyrotoxicosis", Metabolism, 21(5), pp.393~404 (1972)
